# Directive Explanations for Monitoring the Risk of Diabetes Onset: Introducing Directive Data-Centric Explanations and Combinations to Support What-If Explorations

arXiv: https://arxiv.org/abs/2302.10671 · HTML: https://mlsanity.com/paper/2302.10671/

## Key facts

- Cited by 18 papers in the map (data through 14 Oct 2026).
- Builds on 23 of its 58 references that are in the map.
- First posted on arXiv 21 Feb 2023.

## Builds on (most cited first, 23 of 23)

- [A Unified Approach to Interpreting Model Predictions](https://mlsanity.com/paper/1705.07874/) (2017)
- ["Why Should I Trust You?": Explaining the Predictions of Any Classifier](https://mlsanity.com/paper/1602.04938/) (2016)
- [A Survey on Bias and Fairness in Machine Learning](https://mlsanity.com/paper/1908.09635/) (2019)
- [Explanation in Artificial Intelligence: Insights from the Social Sciences](https://mlsanity.com/paper/1706.07269/) (2017)
- [Explaining Machine Learning Classifiers through Diverse Counterfactual Explanations](https://mlsanity.com/paper/1905.07697/) (2019)
- [Actionable Recourse in Linear Classification](https://mlsanity.com/paper/1809.06514/) (2018)
- [Metrics for Explainable AI: Challenges and Prospects](https://mlsanity.com/paper/1812.04608/) (2018)
- [Questioning the AI: Informing Design Practices for Explainable AI User Experiences](https://mlsanity.com/paper/2001.02478/) (2020)
- [Algorithmic Recourse: from Counterfactual Explanations to Interventions](https://mlsanity.com/paper/2002.06278/) (2020)
- [What do we need to build explainable AI systems for the medical domain?](https://mlsanity.com/paper/1712.09923/) (2017)
- [Explainable AI (XAI): A Systematic Meta-Survey of Current Challenges and Future Opportunities](https://mlsanity.com/paper/2111.06420/) (2021)
- [What Do We Want From Explainable Artificial Intelligence (XAI)? -- A Stakeholder Perspective on XAI and a Conceptual Model Guiding Interdisciplinary XAI Research](https://mlsanity.com/paper/2102.07817/) (2021)
- [Human-Centered Tools for Coping with Imperfect Algorithms during Medical Decision-Making](https://mlsanity.com/paper/1902.02960/) (2019)
- [Explainability Fact Sheets: A Framework for Systematic Assessment of Explainable Approaches](https://mlsanity.com/paper/1912.05100/) (2019)
- [DataPerf: Benchmarks for Data-Centric AI Development](https://mlsanity.com/paper/2207.10062/) (2022)
- [Interpretability of machine learning based prediction models in healthcare](https://mlsanity.com/paper/2002.08596/) (2020)
- [explAIner: A Visual Analytics Framework for Interactive and Explainable Machine Learning](https://mlsanity.com/paper/1908.00087/) (2019)
- [Explainable Artificial Intelligence Approaches: A Survey](https://mlsanity.com/paper/2101.09429/) (2021)
- [ViCE: Visual Counterfactual Explanations for Machine Learning Models](https://mlsanity.com/paper/2003.02428/) (2020)
- [Levels of explainable artificial intelligence for human-aligned conversational explanations](https://mlsanity.com/paper/2107.03178/) (2021)
- [Directive Explanations for Actionable Explainability in Machine Learning Applications](https://mlsanity.com/paper/2102.02671/) (2021)
- [AHMoSe: A Knowledge-Based Visual Support System for Selecting Regression Machine Learning Models](https://mlsanity.com/paper/2101.11970/) (2021)
- [Cybertrust: From Explainable to Actionable and Interpretable AI (AI2)](https://mlsanity.com/paper/2201.11117/) (2022)

## Built on by (most cited first, 18 of 18)

- [Is Conversational XAI All You Need? Human-AI Decision Making With a Conversational XAI Assistant](https://mlsanity.com/paper/2501.17546/) (2025)
- [Human-AI collaboration is not very collaborative yet: A taxonomy of interaction patterns in AI-assisted decision making from a systematic review](https://mlsanity.com/paper/2310.19778/) (2023)
- [EXMOS: Explanatory Model Steering Through Multifaceted Explanations and Data Configurations](https://mlsanity.com/paper/2402.00491/) (2024)
- [Explanatory Debiasing: Involving Domain Experts in the Data Generation Process to Mitigate Representation Bias in AI Systems](https://mlsanity.com/paper/2501.01441/) (2024)
- [GlyTwin: Digital Twin for Glucose Control in Type 1 Diabetes Through Optimal Behavioral Modifications Using Patient-Centric Counterfactuals](https://mlsanity.com/paper/2504.09846/) (2025)
- [Lessons Learned from EXMOS User Studies: A Technical Report Summarizing Key Takeaways from User Studies Conducted to Evaluate The EXMOS Platform](https://mlsanity.com/paper/2310.02063/) (2023)
- [An Explanatory Model Steering System for Collaboration between Domain Experts and AI](https://mlsanity.com/paper/2405.13038/) (2024)
- [A Survey on Human-Centered Evaluation of Explainable AI Methods in Clinical Decision Support Systems](https://mlsanity.com/paper/2502.09849/) (2025)
- [On the Design and Evaluation of Human-centered Explainable AI Systems: A Systematic Review and Taxonomy](https://mlsanity.com/paper/2510.12201/) (2025)
- [Show Me How: Benefits and Challenges of Agent-Augmented Counterfactual Explanations for Non-Expert Users](https://mlsanity.com/paper/2504.13897/) (2025)
- [Visual-Conversational Interface for Evidence-Based Explanation of Diabetes Risk Prediction](https://mlsanity.com/paper/2507.02920/) (2025)
- [Interactivity x Explainability: Toward Understanding How Interactivity Can Improve Computer Vision Explanations](https://mlsanity.com/paper/2504.10745/) (2025)
- [Exploring the Impact of Explainable AI and Cognitive Capabilities on Users' Decisions](https://mlsanity.com/paper/2505.01192/) (2025)
- [Comparables XAI: Faithful Example-based AI Explanations with Counterfactual Trace Adjustments](https://mlsanity.com/paper/2602.13784/) (2026)
- [Modular Deep Active Learning Framework for Image Annotation: A Technical Report for the Ophthalmo-AI Project](https://mlsanity.com/paper/2403.15143/) (2024)
- [Explanation User Interfaces: A Systematic Literature Review](https://mlsanity.com/paper/2505.20085/) (2025)
- [When Life Gives You AI, Will You Turn It Into A Market for Lemons? Understanding How Information Asymmetries About AI System Capabilities Affect Market Outcomes and Adoption](https://mlsanity.com/paper/2601.21650/) (2026)
- [Bridging Natural Language and Interactive What-If Interfaces via LLM-Generated Declarative Specifications](https://mlsanity.com/paper/2604.07652/) (2026)

## Abstract (arXiv)

Explainable artificial intelligence is increasingly used in machine learning (ML) based decision-making systems in healthcare. However, little research has compared the utility of different explanation methods in guiding healthcare experts for patient care. Moreover, it is unclear how useful, understandable, actionable and trustworthy these methods are for healthcare experts, as they often require technical ML knowledge. This paper presents an explanation dashboard that predicts the risk of diabetes onset and explains those predictions with data-centric, feature-importance, and example-based explanations. We designed an interactive dashboard to assist healthcare experts, such as nurses and physicians, in monitoring the risk of diabetes onset and recommending measures to minimize risk. We conducted a qualitative study with 11 healthcare experts and a mixed-methods study with 45 healthcare experts and 51 diabetic patients to compare the different explanation methods in our dashboard in terms of understandability, usefulness, actionability, and trust. Results indicate that our participants preferred our representation of data-centric explanations that provide local explanations with a global overview over other methods. Therefore, this paper highlights the importance of visually directive data-centric explanation method for assisting healthcare experts to gain actionable insights from patient health records. Furthermore, we share our design implications for tailoring the visual representation of different explanation methods for healthcare experts.
