# Interpretable Medical Image Visual Question Answering via Multi-Modal Relationship Graph Learning

arXiv: https://arxiv.org/abs/2302.09636 · HTML: https://mlsanity.com/paper/2302.09636/

## Key facts

- Cited by 17 papers in the map (data through 14 Oct 2026).
- Builds on 23 of its 41 references that are in the map.
- First posted on arXiv 19 Feb 2023.

## Builds on (most cited first, 23 of 23)

- [Very Deep Convolutional Networks for Large-Scale Image Recognition](https://mlsanity.com/paper/1409.1556/) (2014)
- [Faster R-CNN: Towards Real-Time Object Detection with Region Proposal Networks](https://mlsanity.com/paper/1506.01497/) (2015)
- [Learning Phrase Representations using RNN Encoder-Decoder for Statistical Machine Translation](https://mlsanity.com/paper/1406.1078/) (2014)
- [Making the V in VQA Matter: Elevating the Role of Image Understanding in Visual Question Answering](https://mlsanity.com/paper/1612.00837/) (2016)
- [VQA: Visual Question Answering](https://mlsanity.com/paper/1505.00468/) (2015)
- [Accurate, Large Minibatch SGD: Training ImageNet in 1 Hour](https://mlsanity.com/paper/1706.02677/) (2017)
- [Bottom-Up and Top-Down Attention for Image Captioning and Visual Question Answering](https://mlsanity.com/paper/1707.07998/) (2017)
- [MIMIC-CXR-JPG, a large publicly available database of labeled chest radiographs](https://mlsanity.com/paper/1901.07042/) (2019)
- [PathVQA: 30000+ Questions for Medical Visual Question Answering](https://mlsanity.com/paper/2003.10286/) (2020)
- [SLAKE: A Semantically-Labeled Knowledge-Enhanced Dataset for Medical Visual Question Answering](https://mlsanity.com/paper/2102.09542/) (2021)
- [VinDr-CXR: An open dataset of chest X-rays with radiologist's annotations](https://mlsanity.com/paper/2012.15029/) (2020)
- [Exploring Visual Relationship for Image Captioning](https://mlsanity.com/paper/1809.07041/) (2018)
- [When Radiology Report Generation Meets Knowledge Graph](https://mlsanity.com/paper/2002.08277/) (2020)
- [Visual Question Answering: A Survey of Methods and Datasets](https://mlsanity.com/paper/1607.05910/) (2016)
- [Relation-Aware Graph Attention Network for Visual Question Answering](https://mlsanity.com/paper/1903.12314/) (2019)
- [Multi-modal Factorized Bilinear Pooling with Co-Attention Learning for Visual Question Answering](https://mlsanity.com/paper/1708.01471/) (2017)
- [Medical Visual Question Answering: A Survey](https://mlsanity.com/paper/2111.10056/) (2021)
- [Ask, Attend and Answer: Exploring Question-Guided Spatial Attention for Visual Question Answering](https://mlsanity.com/paper/1511.05234/) (2015)
- [Where To Look: Focus Regions for Visual Question Answering](https://mlsanity.com/paper/1511.07394/) (2015)
- [Pythia v0.1: the Winning Entry to the VQA Challenge 2018](https://mlsanity.com/paper/1807.09956/) (2018)
- [Multiple Meta-model Quantifying for Medical Visual Question Answering](https://mlsanity.com/paper/2105.08913/) (2021)
- [Learning Conditioned Graph Structures for Interpretable Visual Question Answering](https://mlsanity.com/paper/1806.07243/) (2018)
- [A Structure-Aware Relation Network for Thoracic Diseases Detection and Segmentation](https://mlsanity.com/paper/2104.10326/) (2021)

## Built on by (most cited first, 17 of 17)

- [EHRXQA: A Multi-Modal Question Answering Dataset for Electronic Health Records with Chest X-ray Images](https://mlsanity.com/paper/2310.18652/) (2023)
- [Self-eXplainable AI for Medical Image Analysis: A Survey and New Outlooks](https://mlsanity.com/paper/2410.02331/) (2024)
- [Taming Vision-Language Models for Medical Image Analysis: A Comprehensive Review](https://mlsanity.com/paper/2506.18378/) (2025)
- [CXRAgent: Director-Orchestrated Multi-Stage Reasoning for Chest X-Ray Interpretation](https://mlsanity.com/paper/2510.21324/) (2025)
- [CCD: Mitigating Hallucinations in Radiology MLLMs via Clinical Contrastive Decoding](https://mlsanity.com/paper/2509.23379/) (2025)
- [Developing ChatGPT for Biology and Medicine: A Complete Review of Biomedical Question Answering](https://mlsanity.com/paper/2401.07510/) (2024)
- [Entry-level guide to the use of large language models for medical research](https://mlsanity.com/paper/2410.18856/) (2024)
- [A data- and compute-efficient chest X-ray foundation model beyond aggressive scaling](https://mlsanity.com/paper/2602.22843/) (2026)
- [Computed Tomography Visual Question Answering with Cross-modal Feature Graphing](https://mlsanity.com/paper/2507.04333/) (2025)
- [A unified multimodal understanding and generation model for cross-disciplinary scientific research](https://mlsanity.com/paper/2601.01363/) (2026)
- [Seeing Through Experts Eyes A Foundational Vision Language Model Trained on Radiologists Gaze and Reasoning](https://mlsanity.com/paper/2604.14316/) (2026)
- [Benchmark Success, Clinical Failure: When Reinforcement Learning Optimizes for Benchmarks, Not Patients](https://mlsanity.com/paper/2512.23090/) (2025)
- [Instruction-Free Tuning of Large Vision Language Models for Medical Instruction Following](https://mlsanity.com/paper/2603.19482/) (2026)
- [Learning Superpixel Ensemble and Hierarchy Graphs for Melanoma Detection](https://mlsanity.com/paper/2604.03710/) (2026)
- [Evidential Reasoning Advances Interpretable Real-World Disease Screening](https://mlsanity.com/paper/2605.15171/) (2026)
- [A visual large language foundational model for medical image recognition using clinician-contributed online resources](https://mlsanity.com/paper/2609.06914/) (2026)
- [X-Ragent: Tool-Augmented Reinforcement Learning for Evidence-Grounded Chest X-Ray Reasoning](https://mlsanity.com/paper/2610.16811/) (2026)

## Abstract (arXiv)

Medical visual question answering (VQA) aims to answer clinically relevant questions regarding input medical images. This technique has the potential to improve the efficiency of medical professionals while relieving the burden on the public health system, particularly in resource-poor countries. Existing medical VQA methods tend to encode medical images and learn the correspondence between visual features and questions without exploiting the spatial, semantic, or medical knowledge behind them. This is partially because of the small size of the current medical VQA dataset, which often includes simple questions. Therefore, we first collected a comprehensive and large-scale medical VQA dataset, focusing on chest X-ray images. The questions involved detailed relationships, such as disease names, locations, levels, and types in our dataset. Based on this dataset, we also propose a novel baseline method by constructing three different relationship graphs: spatial relationship, semantic relationship, and implicit relationship graphs on the image regions, questions, and semantic labels. The answer and graph reasoning paths are learned for different questions.
