# Exploiting the Generative Adversarial Network Approach to Create a Synthetic Topography Corneal Image

arXiv: https://arxiv.org/abs/2301.11871 · HTML: https://mlsanity.com/paper/2301.11871/

## Key facts

- No citing papers in the map yet (data through 14 Oct 2026).
- Builds on 18 of its 52 references that are in the map.
- First posted on arXiv 25 Dec 2022.

## Builds on (most cited first, 18 of 18)

- [Deep Residual Learning for Image Recognition](https://mlsanity.com/paper/1512.03385/) (2015)
- [Swin Transformer: Hierarchical Vision Transformer using Shifted Windows](https://mlsanity.com/paper/2103.14030/) (2021)
- [MobileNetV2: Inverted Residuals and Linear Bottlenecks](https://mlsanity.com/paper/1801.04381/) (2018)
- [Image-to-Image Translation with Conditional Adversarial Networks](https://mlsanity.com/paper/1611.07004/) (2016)
- [MobileNets: Efficient Convolutional Neural Networks for Mobile Vision Applications](https://mlsanity.com/paper/1704.04861/) (2017)
- [Xception: Deep Learning with Depthwise Separable Convolutions](https://mlsanity.com/paper/1610.02357/) (2016)
- [Conditional Generative Adversarial Nets](https://mlsanity.com/paper/1411.1784/) (2014)
- [Random Erasing Data Augmentation](https://mlsanity.com/paper/1708.04896/) (2017)
- [StarGAN: Unified Generative Adversarial Networks for Multi-Domain Image-to-Image Translation](https://mlsanity.com/paper/1711.09020/) (2017)
- [CrossViT: Cross-Attention Multi-Scale Vision Transformer for Image Classification](https://mlsanity.com/paper/2103.14899/) (2021)
- [Unsupervised Anomaly Detection with Generative Adversarial Networks to Guide Marker Discovery](https://mlsanity.com/paper/1703.05921/) (2017)
- [Generative Adversarial Network in Medical Imaging: A Review](https://mlsanity.com/paper/1809.07294/) (2018)
- [Co-Scale Conv-Attentional Image Transformers](https://mlsanity.com/paper/2104.06399/) (2021)
- [Energy-based Generative Adversarial Network](https://mlsanity.com/paper/1609.03126/) (2016)
- [Medical Image Synthesis with Context-Aware Generative Adversarial Networks](https://mlsanity.com/paper/1612.05362/) (2016)
- [Transfer Learning without Knowing: Reprogramming Black-box Machine Learning Models with Scarce Data and Limited Resources](https://mlsanity.com/paper/2007.08714/) (2020)
- [SegAN: Adversarial Network with Multi-scale L1 Loss for Medical Image Segmentation](https://mlsanity.com/paper/1706.01805/) (2017)
- [Towards Adversarial Retinal Image Synthesis](https://mlsanity.com/paper/1701.08974/) (2017)

## Abstract (arXiv)

Corneal diseases are the most common eye disorders. Deep learning techniques are used to per-form automated diagnoses of cornea. Deep learning networks require large-scale annotated datasets, which is conceded as a weakness of deep learning. In this work, a method for synthesizing medical images using conditional generative adversarial networks (CGANs), is presented. It also illustrates how produced medical images may be utilized to enrich medical data, improve clinical decisions, and boost the performance of the conventional neural network (CNN) for medical image diagnosis. The study includes using corneal topography captured using a Pentacam device from patients with corneal diseases. The dataset contained 3448 different corneal images. Furthermore, it shows how an unbalanced dataset affects the performance of classifiers, where the data are balanced using the resampling approach. Finally, the results obtained from CNN networks trained on the balanced dataset are compared to those obtained from CNN networks trained on the imbalanced dataset. For performance, the system estimated the diagnosis accuracy, precision, and F1-score metrics. Lastly, some generated images were shown to an expert for evaluation and to see how well experts could identify the type of image and its condition. The expert recognized the image as useful for medical diagnosis and for determining the severity class according to the shape and values, by generating images based on real cases that could be used as new different stages of illness between healthy and unhealthy patients.