# Dual-View Selective Instance Segmentation Network for Unstained Live Adherent Cells in Differential Interference Contrast Images

arXiv: https://arxiv.org/abs/2301.11499 · HTML: https://mlsanity.com/paper/2301.11499/

## Key facts

- Cited by 1 papers in the map (data through 14 Oct 2026).
- Builds on 21 of its 58 references that are in the map.
- First posted on arXiv 27 Jan 2023.

## Builds on (most cited first, 21 of 21)

- [Deep Residual Learning for Image Recognition](https://mlsanity.com/paper/1512.03385/) (2015)
- [PyTorch: An Imperative Style, High-Performance Deep Learning Library](https://mlsanity.com/paper/1912.01703/) (2019)
- [U-Net: Convolutional Networks for Biomedical Image Segmentation](https://mlsanity.com/paper/1505.04597/) (2015)
- [Microsoft COCO: Common Objects in Context](https://mlsanity.com/paper/1405.0312/) (2014)
- [Faster R-CNN: Towards Real-Time Object Detection with Region Proposal Networks](https://mlsanity.com/paper/1506.01497/) (2015)
- [Mask R-CNN](https://mlsanity.com/paper/1703.06870/) (2017)
- [Fully Convolutional Networks for Semantic Segmentation](https://mlsanity.com/paper/1411.4038/) (2014)
- [Fast R-CNN](https://mlsanity.com/paper/1504.08083/) (2015)
- [Aggregated Residual Transformations for Deep Neural Networks](https://mlsanity.com/paper/1611.05431/) (2016)
- [Rich feature hierarchies for accurate object detection and semantic segmentation](https://mlsanity.com/paper/1311.2524/) (2013)
- [MMDetection: Open MMLab Detection Toolbox and Benchmark](https://mlsanity.com/paper/1906.07155/) (2019)
- [Cascade R-CNN: Delving into High Quality Object Detection](https://mlsanity.com/paper/1712.00726/) (2017)
- [Spatial Pyramid Pooling in Deep Convolutional Networks for Visual Recognition](https://mlsanity.com/paper/1406.4729/) (2014)
- [Image Segmentation Using Deep Learning: A Survey](https://mlsanity.com/paper/2001.05566/) (2020)
- [YOLACT: Real-time Instance Segmentation](https://mlsanity.com/paper/1904.02689/) (2019)
- [Deep Multi-modal Object Detection and Semantic Segmentation for Autonomous Driving: Datasets, Methods, and Challenges](https://mlsanity.com/paper/1902.07830/) (2019)
- [Mask Scoring R-CNN](https://mlsanity.com/paper/1903.00241/) (2019)
- [Oriented R-CNN for Object Detection](https://mlsanity.com/paper/2108.05699/) (2021)
- [MMRotate: A Rotated Object Detection Benchmark using PyTorch](https://mlsanity.com/paper/2204.13317/) (2022)
- [InstaBoost: Boosting Instance Segmentation via Probability Map Guided Copy-Pasting](https://mlsanity.com/paper/1908.07801/) (2019)
- [Unseen Object Instance Segmentation for Robotic Environments](https://mlsanity.com/paper/2007.08073/) (2020)

## Built on by (most cited first, 1 of 1)

- [A Global and Patch-wise Contrastive Loss for Accurate Automated Exudate Detection](https://mlsanity.com/paper/2302.11517/) (2023)

## Abstract (arXiv)

Despite recent advances in data-independent and deep-learning algorithms, unstained live adherent cell instance segmentation remains a long-standing challenge in cell image processing. Adherent cells' inherent visual characteristics, such as low contrast structures, fading edges, and irregular morphology, have made it difficult to distinguish from one another, even by human experts, let alone computational methods. In this study, we developed a novel deep-learning algorithm called dual-view selective instance segmentation network (DVSISN) for segmenting unstained adherent cells in differential interference contrast (DIC) images. First, we used a dual-view segmentation (DVS) method with pairs of original and rotated images to predict the bounding box and its corresponding mask for each cell instance. Second, we used a mask selection (MS) method to filter the cell instances predicted by the DVS to keep masks closest to the ground truth only. The developed algorithm was trained and validated on our dataset containing 520 images and 12198 cells. Experimental results demonstrate that our algorithm achieves an AP_segm of 0.555, which remarkably overtakes a benchmark by a margin of 23.6%. This study's success opens up a new possibility of using rotated images as input for better prediction in cell images.