# SACDNet: Towards Early Type 2 Diabetes Prediction with Uncertainty for Electronic Health Records

arXiv: https://arxiv.org/abs/2301.04844 · HTML: https://mlsanity.com/paper/2301.04844/

## Key facts

- Cited by 1 papers in the map (data through 14 Oct 2026).
- Builds on 10 of its 96 references that are in the map.
- First posted on arXiv 12 Jan 2023.

## Builds on (most cited first, 10 of 10)

- [Intriguing properties of neural networks](https://mlsanity.com/paper/1312.6199/) (2013)
- [Neural Machine Translation by Jointly Learning to Align and Translate](https://mlsanity.com/paper/1409.0473/) (2014)
- [Dropout as a Bayesian Approximation: Representing Model Uncertainty in Deep Learning](https://mlsanity.com/paper/1506.02142/) (2015)
- [Deep Bayesian Active Learning with Image Data](https://mlsanity.com/paper/1703.02910/) (2017)
- [Deep Neural Networks are Easily Fooled: High Confidence Predictions for Unrecognizable Images](https://mlsanity.com/paper/1412.1897/) (2014)
- [A Survey of Uncertainty in Deep Neural Networks](https://mlsanity.com/paper/2107.03342/) (2021)
- [Exploring Uncertainty Measures in Deep Networks for Multiple Sclerosis Lesion Detection and Segmentation](https://mlsanity.com/paper/1808.01200/) (2018)
- [A Comprehensive guide to Bayesian Convolutional Neural Network with Variational Inference](https://mlsanity.com/paper/1901.02731/) (2019)
- [Bayesian QuickNAT: Model Uncertainty in Deep Whole-Brain Segmentation for Structure-wise Quality Control](https://mlsanity.com/paper/1811.09800/) (2018)
- [Towards calibrated and scalable uncertainty representations for neural networks](https://mlsanity.com/paper/1911.00104/) (2019)

## Built on by (most cited first, 1 of 1)

- [Deep Learning-Based Noninvasive Screening of Type 2 Diabetes with Chest X-ray Images and Electronic Health Records](https://mlsanity.com/paper/2412.10955/) (2024)

## Abstract (arXiv)

Type 2 diabetes mellitus (T2DM) is one of the most common diseases and a leading cause of death. The problem of early diagnosis of T2DM is challenging and necessary to prevent serious complications. This study proposes a novel neural network architecture for early T2DM prediction using multi-headed self-attention and dense layers to extract features from historic diagnoses, patient vitals, and demographics. The proposed technique is called the Self-Attention for Comorbid Disease Net (SACDNet), achieving an accuracy of 89.3% and an F1-Score of 89.1%, having a 1.6% increased accuracy and 1.3% increased f1-score compared to the baseline techniques. Monte Carlo (MC) Dropout is applied to the SACDNet to get a bayesian approximation. A T2DM prediction framework based on the MC Dropout SACDNet is proposed to quantize the uncertainty associated with the predictions. A T2DM prediction dataset is also built as part of this study which is based on real-world routine Electronic Health Record (EHR) data comprising 4,124 diabetic and 181,767 non-diabetic examples, collected from 295 different EHR systems running in different parts of the United States of America. This dataset is further used to evaluate 7 different machine learning and 3 deep learning-based models. Finally, a detailed analysis of the fairness of every technique against different patient demographic groups is performed to validate the unbiased generalization of the techniques and the diversity of the data.
