# EndoBoost: a plug-and-play module for false positive suppression during computer-aided polyp detection in real-world colonoscopy (with dataset)

arXiv: https://arxiv.org/abs/2212.12204 · HTML: https://mlsanity.com/paper/2212.12204/

## Key facts

- No citing papers in the map yet (data through 14 Oct 2026).
- Builds on 28 of its 68 references that are in the map.
- First posted on arXiv 23 Dec 2022.

## Builds on (most cited first, 28 of 28)

- [Deep Residual Learning for Image Recognition](https://mlsanity.com/paper/1512.03385/) (2015)
- [PyTorch: An Imperative Style, High-Performance Deep Learning Library](https://mlsanity.com/paper/1912.01703/) (2019)
- [Faster R-CNN: Towards Real-Time Object Detection with Region Proposal Networks](https://mlsanity.com/paper/1506.01497/) (2015)
- [You Only Look Once: Unified, Real-Time Object Detection](https://mlsanity.com/paper/1506.02640/) (2015)
- [Auto-Encoding Variational Bayes](https://mlsanity.com/paper/1312.6114/) (2013)
- [UMAP: Uniform Manifold Approximation and Projection for Dimension Reduction](https://mlsanity.com/paper/1802.03426/) (2018)
- [A Baseline for Detecting Misclassified and Out-of-Distribution Examples in Neural Networks](https://mlsanity.com/paper/1610.02136/) (2016)
- [Density estimation using Real NVP](https://mlsanity.com/paper/1605.08803/) (2016)
- [Glow: Generative Flow with Invertible 1x1 Convolutions](https://mlsanity.com/paper/1807.03039/) (2018)
- [Normalizing Flows for Probabilistic Modeling and Inference](https://mlsanity.com/paper/1912.02762/) (2019)
- [NICE: Non-linear Independent Components Estimation](https://mlsanity.com/paper/1410.8516/) (2014)
- [Deep Anomaly Detection with Outlier Exposure](https://mlsanity.com/paper/1812.04606/) (2018)
- [Deep Neural Networks are Easily Fooled: High Confidence Predictions for Unrecognizable Images](https://mlsanity.com/paper/1412.1897/) (2014)
- [Kvasir-SEG: A Segmented Polyp Dataset](https://mlsanity.com/paper/1911.07069/) (2019)
- [Likelihood Ratios for Out-of-Distribution Detection](https://mlsanity.com/paper/1906.02845/) (2019)
- [Do Deep Generative Models Know What They Don't Know?](https://mlsanity.com/paper/1810.09136/) (2018)
- [A Unifying Review of Deep and Shallow Anomaly Detection](https://mlsanity.com/paper/2009.11732/) (2020)
- [Invertible Residual Networks](https://mlsanity.com/paper/1811.00995/) (2018)
- [Residual Flows for Invertible Generative Modeling](https://mlsanity.com/paper/1906.02735/) (2019)
- [Why Normalizing Flows Fail to Detect Out-of-Distribution Data](https://mlsanity.com/paper/2006.08545/) (2020)
- [Same Same But DifferNet: Semi-Supervised Defect Detection with Normalizing Flows](https://mlsanity.com/paper/2008.12577/) (2020)
- [Hybrid Models for Open Set Recognition](https://mlsanity.com/paper/2003.12506/) (2020)
- [Understanding Anomaly Detection with Deep Invertible Networks through Hierarchies of Distributions and Features](https://mlsanity.com/paper/2006.10848/) (2020)
- [Kvasir-Instrument: Diagnostic and therapeutic tool segmentation dataset in gastrointestinal endoscopy](https://mlsanity.com/paper/2011.08065/) (2020)
- [Assessing generalisability of deep learning-based polyp detection and segmentation methods through a computer vision challenge](https://mlsanity.com/paper/2202.12031/) (2022)
- [A deep learning framework for quality assessment and restoration in video endoscopy](https://mlsanity.com/paper/1904.07073/) (2019)
- [Unsupervised Video Anomaly Detection via Normalizing Flows with Implicit Latent Features](https://mlsanity.com/paper/2010.07524/) (2020)
- [Endoscopy artifact detection (EAD 2019) challenge dataset](https://mlsanity.com/paper/1905.03209/) (2019)

## Abstract (arXiv)

The advance of computer-aided detection systems using deep learning opened a new scope in endoscopic image analysis. However, the learning-based models developed on closed datasets are susceptible to unknown anomalies in complex clinical environments. In particular, the high false positive rate of polyp detection remains a major challenge in clinical practice. In this work, we release the FPPD-13 dataset, which provides a taxonomy and real-world cases of typical false positives during computer-aided polyp detection in real-world colonoscopy. We further propose a post-hoc module EndoBoost, which can be plugged into generic polyp detection models to filter out false positive predictions. This is realized by generative learning of the polyp manifold with normalizing flows and rejecting false positives through density estimation. Compared to supervised classification, this anomaly detection paradigm achieves better data efficiency and robustness in open-world settings. Extensive experiments demonstrate a promising false positive suppression in both retrospective and prospective validation. In addition, the released dataset can be used to perform 'stress' tests on established detection systems and encourages further research toward robust and reliable computer-aided endoscopic image analysis. The dataset and code will be publicly available at http://endoboost.miccai.cloud.