# Predicting Survival of Tongue Cancer Patients by Machine Learning Models

arXiv: https://arxiv.org/abs/2212.12114 · HTML: https://mlsanity.com/paper/2212.12114/

## Key facts

- No citing papers in the map yet (data through 14 Oct 2026).
- Builds on 2 of its 26 references that are in the map.
- First posted on arXiv 23 Dec 2022.

## Builds on (most cited first, 2 of 2)

- [XGBoost: A Scalable Tree Boosting System](https://mlsanity.com/paper/1603.02754/) (2016)
- [Prediction of Drug-Induced TdP Risks Using Machine Learning and Rabbit Ventricular Wedge Assay](https://mlsanity.com/paper/2201.05669/) (2022)

## Abstract (arXiv)

Tongue cancer is a common oral cavity malignancy that originates in the mouth and throat. Much effort has been invested in improving its diagnosis, treatment, and management. Surgical removal, chemotherapy, and radiation therapy remain the major treatment for tongue cancer. The survival of patients determines the treatment effect. Previous studies have identified certain survival and risk factors based on descriptive statistics, ignoring the complex, nonlinear relationship among clinical and demographic variables. In this study, we utilize five cutting-edge machine learning models and clinical data to predict the survival of tongue cancer patients after treatment. Five-fold cross-validation, bootstrap analysis, and permutation feature importance are applied to estimate and interpret model performance. The prognostic factors identified by our method are consistent with previous clinical studies. Our method is accurate, interpretable, and thus useable as additional evidence in tongue cancer treatment and management.