# Double U-Net for Super-Resolution and Segmentation of Live Cell Images

arXiv: https://arxiv.org/abs/2212.02028 · HTML: https://mlsanity.com/paper/2212.02028/

## Key facts

- Cited by 1 papers in the map (data through 14 Oct 2026).
- Builds on 8 of its 20 references that are in the map.
- First posted on arXiv 5 Dec 2022.

## Builds on (most cited first, 8 of 8)

- [U-Net: Convolutional Networks for Biomedical Image Segmentation](https://mlsanity.com/paper/1505.04597/) (2015)
- [UNet++: A Nested U-Net Architecture for Medical Image Segmentation](https://mlsanity.com/paper/1807.10165/) (2018)
- [MultiResUNet : Rethinking the U-Net Architecture for Multimodal Biomedical Image Segmentation](https://mlsanity.com/paper/1902.04049/) (2019)
- [Optimizing the Dice Score and Jaccard Index for Medical Image Segmentation: Theory & Practice](https://mlsanity.com/paper/1911.01685/) (2019)
- [Efficient and Accurate MRI Super-Resolution using a Generative Adversarial Network and 3D Multi-Level Densely Connected Network](https://mlsanity.com/paper/1803.01417/) (2018)
- [RAISR: Rapid and Accurate Image Super Resolution](https://mlsanity.com/paper/1606.01299/) (2016)
- [Generalised Wasserstein Dice Score for Imbalanced Multi-class Segmentation using Holistic Convolutional Networks](https://mlsanity.com/paper/1707.00478/) (2017)
- [Brain Tumor Segmentation Based on Refined Fully Convolutional Neural Networks with A Hierarchical Dice Loss](https://mlsanity.com/paper/1712.09093/) (2017)

## Built on by (most cited first, 1 of 1)

- [A residual dense vision transformer for medical image super-resolution with segmentation-based perceptual loss fine-tuning](https://mlsanity.com/paper/2302.11184/) (2023)

## Abstract (arXiv)

Accurate segmentation of live cell images has broad applications in clinical and research contexts. Deep learning methods have been able to perform cell segmentations with high accuracy; however developing machine learning models to do this requires access to high fidelity images of live cells. This is often not available due to resource constraints like limited accessibility to high performance microscopes or due to the nature of the studied organisms. Segmentation on low resolution images of live cells is a difficult task. This paper proposes a method to perform live cell segmentation with low resolution images by performing super-resolution as a pre-processing step in the segmentation pipeline.