# Using Large Pre-Trained Language Model to Assist FDA in Premarket Medical Device

arXiv: https://arxiv.org/abs/2212.01217 · HTML: https://mlsanity.com/paper/2212.01217/

## Key facts

- No citing papers in the map yet (data through 14 Oct 2026).
- Builds on 20 of its 36 references that are in the map.
- First posted on arXiv 3 Nov 2022.

## Builds on (most cited first, 20 of 20)

- [BERT: Pre-training of Deep Bidirectional Transformers for Language Understanding](https://mlsanity.com/paper/1810.04805/) (2018)
- [Language Models are Few-Shot Learners](https://mlsanity.com/paper/2005.14165/) (2020)
- [Exploring the Limits of Transfer Learning with a Unified Text-to-Text Transformer](https://mlsanity.com/paper/1910.10683/) (2019)
- [RoBERTa: A Robustly Optimized BERT Pretraining Approach](https://mlsanity.com/paper/1907.11692/) (2019)
- [Sentence-BERT: Sentence Embeddings using Siamese BERT-Networks](https://mlsanity.com/paper/1908.10084/) (2019)
- [On the Opportunities and Risks of Foundation Models](https://mlsanity.com/paper/2108.07258/) (2021)
- [Enriching Word Vectors with Subword Information](https://mlsanity.com/paper/1607.04606/) (2016)
- [Don't Stop Pretraining: Adapt Language Models to Domains and Tasks](https://mlsanity.com/paper/2004.10964/) (2020)
- [Convolutional Neural Networks for Sentence Classification](https://mlsanity.com/paper/1408.5882/) (2014)
- [MPNet: Masked and Permuted Pre-training for Language Understanding](https://mlsanity.com/paper/2004.09297/) (2020)
- [Adversarial Examples Are Not Bugs, They Are Features](https://mlsanity.com/paper/1905.02175/) (2019)
- [Bag of Tricks for Efficient Text Classification](https://mlsanity.com/paper/1607.01759/) (2016)
- [Fine-Tuning can Distort Pretrained Features and Underperform Out-of-Distribution](https://mlsanity.com/paper/2202.10054/) (2022)
- [Adversarial Robustness: From Self-Supervised Pre-Training to Fine-Tuning](https://mlsanity.com/paper/2003.12862/) (2020)
- [When and Why are Pre-trained Word Embeddings Useful for Neural Machine Translation?](https://mlsanity.com/paper/1804.06323/) (2018)
- [Lifelong Pretraining: Continually Adapting Language Models to Emerging Corpora](https://mlsanity.com/paper/2110.08534/) (2021)
- [On the Sentence Embeddings from Pre-trained Language Models](https://mlsanity.com/paper/2011.05864/) (2020)
- [Adapt-and-Distill: Developing Small, Fast and Effective Pretrained Language Models for Domains](https://mlsanity.com/paper/2106.13474/) (2021)
- [Improving the Adversarial Robustness of NLP Models by Information Bottleneck](https://mlsanity.com/paper/2206.05511/) (2022)
- [Learning Stable Classifiers by Transferring Unstable Features](https://mlsanity.com/paper/2106.07847/) (2021)

## Abstract (arXiv)

This paper proposes a possible method using natural language processing that might assist in the FDA medical device marketing process. Actual device descriptions are taken and matched with the device description in FDA Title 21 of CFR to determine their corresponding device type. Both pre-trained word embeddings such as FastText and large pre-trained sentence embedding models such as sentence transformers are evaluated on their accuracy in characterizing a piece of device description. An experiment is also done to test whether these models can identify the devices wrongly classified in the FDA database. The result shows that sentence transformer with T5 and MPNet and GPT-3 semantic search embedding show high accuracy in identifying the correct classification by narrowing down the correct label to be contained in the first 15 most likely results, as compared to 2585 types of device descriptions that must be manually searched through. On the other hand, all methods demonstrate high accuracy in identifying completely incorrectly labeled devices, but all fail to identify false device classifications that are wrong but closely related to the true label.