# Single Slice Thigh CT Muscle Group Segmentation with Domain Adaptation and Self-Training

arXiv: https://arxiv.org/abs/2212.00059 · HTML: https://mlsanity.com/paper/2212.00059/

## Key facts

- Cited by 1 papers in the map (data through 14 Oct 2026).
- Builds on 13 of its 41 references that are in the map.
- First posted on arXiv 30 Nov 2022.

## Builds on (most cited first, 13 of 13)

- [U-Net: Convolutional Networks for Biomedical Image Segmentation](https://mlsanity.com/paper/1505.04597/) (2015)
- [ADVENT: Adversarial Entropy Minimization for Domain Adaptation in Semantic Segmentation](https://mlsanity.com/paper/1811.12833/) (2018)
- [Confidence Regularized Self-Training](https://mlsanity.com/paper/1908.09822/) (2019)
- [A Survey of Unsupervised Deep Domain Adaptation](https://mlsanity.com/paper/1812.02849/) (2018)
- [Domain Adaptation for Medical Image Analysis: A Survey](https://mlsanity.com/paper/2102.09508/) (2021)
- [Unsupervised Intra-domain Adaptation for Semantic Segmentation through Self-Supervision](https://mlsanity.com/paper/2004.07703/) (2020)
- [Unsupervised Bidirectional Cross-Modality Adaptation via Deeply Synergistic Image and Feature Alignment for Medical Image Segmentation](https://mlsanity.com/paper/2002.02255/) (2020)
- [All about Structure: Adapting Structural Information across Domains for Boosting Semantic Segmentation](https://mlsanity.com/paper/1903.12212/) (2019)
- [SynSeg-Net: Synthetic Segmentation Without Target Modality Ground Truth](https://mlsanity.com/paper/1810.06498/) (2018)
- [Unsupervised Domain Adaptation via Disentangled Representations: Application to Cross-Modality Liver Segmentation](https://mlsanity.com/paper/1907.13590/) (2019)
- [Anatomy-Constrained Contrastive Learning for Synthetic Segmentation without Ground-truth](https://mlsanity.com/paper/2107.05482/) (2021)
- [Reducing Positional Variance in Cross-sectional Abdominal CT Slices with Deep Conditional Generative Models](https://mlsanity.com/paper/2209.14467/) (2022)
- [Longitudinal Variability Analysis on Low-dose Abdominal CT with Deep Learning-based Segmentation](https://mlsanity.com/paper/2209.14217/) (2022)

## Built on by (most cited first, 1 of 1)

- [Enhancing Hierarchical Transformers for Whole Brain Segmentation with Intracranial Measurements Integration](https://mlsanity.com/paper/2309.04071/) (2023)

## Abstract (arXiv)

Objective: Thigh muscle group segmentation is important for assessment of muscle anatomy, metabolic disease and aging. Many efforts have been put into quantifying muscle tissues with magnetic resonance (MR) imaging including manual annotation of individual muscles. However, leveraging publicly available annotations in MR images to achieve muscle group segmentation on single slice computed tomography (CT) thigh images is challenging. Method: We propose an unsupervised domain adaptation pipeline with self-training to transfer labels from 3D MR to single CT slice. First, we transform the image appearance from MR to CT with CycleGAN and feed the synthesized CT images to a segmenter simultaneously. Single CT slices are divided into hard and easy cohorts based on the entropy of pseudo labels inferenced by the segmenter. After refining easy cohort pseudo labels based on anatomical assumption, self-training with easy and hard splits is applied to fine tune the segmenter. Results: On 152 withheld single CT thigh images, the proposed pipeline achieved a mean Dice of 0.888(0.041) across all muscle groups including sartorius, hamstrings, quadriceps femoris and gracilis. muscles Conclusion: To our best knowledge, this is the first pipeline to achieve thigh imaging domain adaptation from MR to CT. The proposed pipeline is effective and robust in extracting muscle groups on 2D single slice CT thigh images.The container is available for public use at https://github.com/MASILab/DA_CT_muscle_seg