# Neurodevelopmental Phenotype Prediction: A State-of-the-Art Deep Learning Model

arXiv: https://arxiv.org/abs/2211.08831 · HTML: https://mlsanity.com/paper/2211.08831/

## Key facts

- Cited by 1 papers in the map (data through 14 Oct 2026).
- Builds on 12 of its 34 references that are in the map.
- First posted on arXiv 16 Nov 2022.

## Builds on (most cited first, 12 of 12)

- [Deep Residual Learning for Image Recognition](https://mlsanity.com/paper/1512.03385/) (2015)
- [An Image is Worth 16x16 Words: Transformers for Image Recognition at Scale](https://mlsanity.com/paper/2010.11929/) (2020)
- [Graph Attention Networks](https://mlsanity.com/paper/1710.10903/) (2017)
- [A Unified Approach to Interpreting Model Predictions](https://mlsanity.com/paper/1705.07874/) (2017)
- [Convolutional Neural Networks on Graphs with Fast Localized Spectral Filtering](https://mlsanity.com/paper/1606.09375/) (2016)
- [Learning Important Features Through Propagating Activation Differences](https://mlsanity.com/paper/1704.02685/) (2017)
- [Geometric Deep Learning: Grids, Groups, Graphs, Geodesics, and Gauges](https://mlsanity.com/paper/2104.13478/) (2021)
- [Geometric deep learning on graphs and manifolds using mixture model CNNs](https://mlsanity.com/paper/1611.08402/) (2016)
- [Spherical CNNs](https://mlsanity.com/paper/1801.10130/) (2018)
- [DeepSphere: a graph-based spherical CNN](https://mlsanity.com/paper/2012.15000/) (2020)
- [Spherical U-Net on Cortical Surfaces: Methods and Applications](https://mlsanity.com/paper/1904.00906/) (2019)
- [Surface Vision Transformers: Attention-Based Modelling applied to Cortical Analysis](https://mlsanity.com/paper/2203.16414/) (2022)

## Built on by (most cited first, 1 of 1)

- [LaB-GATr: geometric algebra transformers for large biomedical surface and volume meshes](https://mlsanity.com/paper/2403.07536/) (2024)

## Abstract (arXiv)

A major challenge in medical image analysis is the automated detection of biomarkers from neuroimaging data. Traditional approaches, often based on image registration, are limited in capturing the high variability of cortical organisation across individuals. Deep learning methods have been shown to be successful in overcoming this difficulty, and some of them have even outperformed medical professionals on certain datasets. In this paper, we apply a deep neural network to analyse the cortical surface data of neonates, derived from the publicly available Developing Human Connectome Project (dHCP). Our goal is to identify neurodevelopmental biomarkers and to predict gestational age at birth based on these biomarkers. Using scans of preterm neonates acquired around the term-equivalent age, we were able to investigate the impact of preterm birth on cortical growth and maturation during late gestation. Besides reaching state-of-the-art prediction accuracy, the proposed model has much fewer parameters than the baselines, and its error stays low on both unregistered and registered cortical surfaces.