# Modular Clinical Decision Support Networks (MoDN) -- Updatable, Interpretable, and Portable Predictions for Evolving Clinical Environments

arXiv: https://arxiv.org/abs/2211.06637 · HTML: https://mlsanity.com/paper/2211.06637/

## Key facts

- Cited by 2 papers in the map (data through 14 Oct 2026).
- Builds on 4 of its 45 references that are in the map.
- First posted on arXiv 12 Nov 2022.

## Builds on (most cited first, 4 of 4)

- [Adam: A Method for Stochastic Optimization](https://mlsanity.com/paper/1412.6980/) (2014)
- [PyTorch: An Imperative Style, High-Performance Deep Learning Library](https://mlsanity.com/paper/1912.01703/) (2019)
- [A Survey on Bias and Fairness in Machine Learning](https://mlsanity.com/paper/1908.09635/) (2019)
- [Scalable and accurate deep learning for electronic health records](https://mlsanity.com/paper/1801.07860/) (2018)

## Built on by (most cited first, 2 of 2)

- [MultiModN- Multimodal, Multi-Task, Interpretable Modular Networks](https://mlsanity.com/paper/2309.14118/) (2023)
- [Leveraging Generic Foundation Models for Multimodal Surgical Data Analysis](https://mlsanity.com/paper/2509.06831/) (2025)

## Abstract (arXiv)

Data-driven Clinical Decision Support Systems (CDSS) have the potential to improve and standardise care with personalised probabilistic guidance. However, the size of data required necessitates collaborative learning from analogous CDSS's, which are often unsharable or imperfectly interoperable (IIO), meaning their feature sets are not perfectly overlapping. We propose Modular Clinical Decision Support Networks (MoDN) which allow flexible, privacy-preserving learning across IIO datasets, while providing interpretable, continuous predictive feedback to the clinician. MoDN is a novel decision tree composed of feature-specific neural network modules. It creates dynamic personalised representations of patients, and can make multiple predictions of diagnoses, updatable at each step of a consultation. The modular design allows it to compartmentalise training updates to specific features and collaboratively learn between IIO datasets without sharing any data.
