# Dual Multi-scale Mean Teacher Network for Semi-supervised Infection Segmentation in Chest CT Volume for COVID-19

arXiv: https://arxiv.org/abs/2211.05548 · HTML: https://mlsanity.com/paper/2211.05548/

## Key facts

- Cited by 4 papers in the map (data through 14 Oct 2026).
- Builds on 27 of its 60 references that are in the map.
- First posted on arXiv 10 Nov 2022.

## Builds on (most cited first, 27 of 27)

- [U-Net: Convolutional Networks for Biomedical Image Segmentation](https://mlsanity.com/paper/1505.04597/) (2015)
- [V-Net: Fully Convolutional Neural Networks for Volumetric Medical Image Segmentation](https://mlsanity.com/paper/1606.04797/) (2016)
- [UNet++: A Nested U-Net Architecture for Medical Image Segmentation](https://mlsanity.com/paper/1807.10165/) (2018)
- [3D U-Net: Learning Dense Volumetric Segmentation from Sparse Annotation](https://mlsanity.com/paper/1606.06650/) (2016)
- [Holistically-Nested Edge Detection](https://mlsanity.com/paper/1504.06375/) (2015)
- [Deep Layer Aggregation](https://mlsanity.com/paper/1707.06484/) (2017)
- [Uncertainty-aware Self-ensembling Model for Semi-supervised 3D Left Atrium Segmentation](https://mlsanity.com/paper/1907.07034/) (2019)
- [Inf-Net: Automatic COVID-19 Lung Infection Segmentation from CT Images](https://mlsanity.com/paper/2004.14133/) (2020)
- [Not-so-supervised: a survey of semi-supervised, multi-instance, and transfer learning in medical image analysis](https://mlsanity.com/paper/1804.06353/) (2018)
- [MosMedData: Chest CT Scans With COVID-19 Related Findings Dataset](https://mlsanity.com/paper/2005.06465/) (2020)
- [Review of Artificial Intelligence Techniques in Imaging Data Acquisition, Segmentation and Diagnosis for COVID-19](https://mlsanity.com/paper/2004.02731/) (2020)
- [JCS: An Explainable COVID-19 Diagnosis System by Joint Classification and Segmentation](https://mlsanity.com/paper/2004.07054/) (2020)
- [CT-Realistic Lung Nodule Simulation from 3D Conditional Generative Adversarial Networks for Robust Lung Segmentation](https://mlsanity.com/paper/1806.04051/) (2018)
- [Automated Design of Deep Learning Methods for Biomedical Image Segmentation](https://mlsanity.com/paper/1904.08128/) (2019)
- [Residual Attention U-Net for Automated Multi-Class Segmentation of COVID-19 Chest CT Images](https://mlsanity.com/paper/2004.05645/) (2020)
- [MiniSeg: An Extremely Minimum Network for Efficient COVID-19 Segmentation](https://mlsanity.com/paper/2004.09750/) (2020)
- [Unsupervised Domain Adaptation for Automatic Estimation of Cardiothoracic Ratio](https://mlsanity.com/paper/1807.03434/) (2018)
- [Diagnosis of Coronavirus Disease 2019 (COVID-19) with Structured Latent Multi-View Representation Learning](https://mlsanity.com/paper/2005.03227/) (2020)
- [Relational Modeling for Robust and Efficient Pulmonary Lobe Segmentation in CT Scans](https://mlsanity.com/paper/2004.07443/) (2020)
- [COVID-19 Chest CT Image Segmentation -- A Deep Convolutional Neural Network Solution](https://mlsanity.com/paper/2004.10987/) (2020)
- [Synergistic Learning of Lung Lobe Segmentation and Hierarchical Multi-Instance Classification for Automated Severity Assessment of COVID-19 in CT Images](https://mlsanity.com/paper/2005.03832/) (2020)
- [Progressive and Multi-Path Holistically Nested Neural Networks for Pathological Lung Segmentation from CT Images](https://mlsanity.com/paper/1706.03702/) (2017)
- [Severity Assessment of Coronavirus Disease 2019 (COVID-19) Using Quantitative Features from Chest CT Images](https://mlsanity.com/paper/2003.11988/) (2020)
- [AI-Driven CT-based quantification, staging and short-term outcome prediction of COVID-19 pneumonia](https://mlsanity.com/paper/2004.12852/) (2020)
- [Beyond CNNs: Exploiting Further Inherent Symmetries in Medical Image Segmentation](https://mlsanity.com/paper/2207.14472/) (2022)
- [Automated Quantification of CT Patterns Associated with COVID-19 from Chest CT](https://mlsanity.com/paper/2004.01279/) (2020)
- [Angle-Closure Detection in Anterior Segment OCT based on Multi-Level Deep Network](https://mlsanity.com/paper/1902.03585/) (2019)

## Built on by (most cited first, 4 of 4)

- [Dual-scale Enhanced and Cross-generative Consistency Learning for Semi-supervised Medical Image Segmentation](https://mlsanity.com/paper/2312.16039/) (2023)
- [Inter- and intra-uncertainty based feature aggregation model for semi-supervised histopathology image segmentation](https://mlsanity.com/paper/2403.12767/) (2024)
- [ContrasInver: Ultra-Sparse Label Semi-supervised Regression for Multi-dimensional Seismic Inversion](https://mlsanity.com/paper/2302.06441/) (2023)
- [Iterative pseudo-labeling based adaptive copy-paste supervision for semi-supervised tumor segmentation](https://mlsanity.com/paper/2508.04044/) (2025)

## Abstract (arXiv)

Automated detecting lung infections from computed tomography (CT) data plays an important role for combating COVID-19. However, there are still some challenges for developing AI system. 1) Most current COVID-19 infection segmentation methods mainly relied on 2D CT images, which lack 3D sequential constraint. 2) Existing 3D CT segmentation methods focus on single-scale representations, which do not achieve the multiple level receptive field sizes on 3D volume. 3) The emergent breaking out of COVID-19 makes it hard to annotate sufficient CT volumes for training deep model. To address these issues, we first build a multiple dimensional-attention convolutional neural network (MDA-CNN) to aggregate multi-scale information along different dimension of input feature maps and impose supervision on multiple predictions from different CNN layers. Second, we assign this MDA-CNN as a basic network into a novel dual multi-scale mean teacher network (DM2T-Net) for semi-supervised COVID-19 lung infection segmentation on CT volumes by leveraging unlabeled data and exploring the multi-scale information. Our DM2T-Net encourages multiple predictions at different CNN layers from the student and teacher networks to be consistent for computing a multi-scale consistency loss on unlabeled data, which is then added to the supervised loss on the labeled data from multiple predictions of MDA-CNN. Third, we collect two COVID-19 segmentation datasets to evaluate our method. The experimental results show that our network consistently outperforms the compared state-of-the-art methods.
