# Analysing the effectiveness of a generative model for semi-supervised medical image segmentation

arXiv: https://arxiv.org/abs/2211.01886 · HTML: https://mlsanity.com/paper/2211.01886/

## Key facts

- Cited by 1 papers in the map (data through 14 Oct 2026).
- Builds on 30 of its 57 references that are in the map.
- First posted on arXiv 3 Nov 2022.

## Builds on (most cited first, 30 of 30)

- [Deep Residual Learning for Image Recognition](https://mlsanity.com/paper/1512.03385/) (2015)
- [Adam: A Method for Stochastic Optimization](https://mlsanity.com/paper/1412.6980/) (2014)
- [U-Net: Convolutional Networks for Biomedical Image Segmentation](https://mlsanity.com/paper/1505.04597/) (2015)
- [The Unreasonable Effectiveness of Deep Features as a Perceptual Metric](https://mlsanity.com/paper/1801.03924/) (2018)
- [Densely Connected Convolutional Networks](https://mlsanity.com/paper/1608.06993/) (2016)
- [Analyzing and Improving the Image Quality of StyleGAN](https://mlsanity.com/paper/1912.04958/) (2019)
- [Rethinking Atrous Convolution for Semantic Image Segmentation](https://mlsanity.com/paper/1706.05587/) (2017)
- [CheXpert: A Large Chest Radiograph Dataset with Uncertainty Labels and Expert Comparison](https://mlsanity.com/paper/1901.07031/) (2019)
- [High-Resolution Image Synthesis and Semantic Manipulation with Conditional GANs](https://mlsanity.com/paper/1711.11585/) (2017)
- [ChestX-ray8: Hospital-scale Chest X-ray Database and Benchmarks on Weakly-Supervised Classification and Localization of Common Thorax Diseases](https://mlsanity.com/paper/1705.02315/) (2017)
- [Semi-Supervised Learning with Deep Generative Models](https://mlsanity.com/paper/1406.5298/) (2014)
- [Semi-Supervised Semantic Segmentation with Cross-Consistency Training](https://mlsanity.com/paper/2003.09005/) (2020)
- [Adversarial Feature Learning](https://mlsanity.com/paper/1605.09782/) (2016)
- [nnU-Net: Self-adapting Framework for U-Net-Based Medical Image Segmentation](https://mlsanity.com/paper/1809.10486/) (2018)
- [A Survey on Deep Semi-supervised Learning](https://mlsanity.com/paper/2103.00550/) (2021)
- [Semi-Supervised Semantic Segmentation Using Unreliable Pseudo-Labels](https://mlsanity.com/paper/2203.03884/) (2022)
- [Adversarially Learned Inference](https://mlsanity.com/paper/1606.00704/) (2016)
- [Adversarial Learning for Semi-Supervised Semantic Segmentation](https://mlsanity.com/paper/1802.07934/) (2018)
- [Semantic Segmentation with Generative Models: Semi-Supervised Learning and Strong Out-of-Domain Generalization](https://mlsanity.com/paper/2104.05833/) (2021)
- [Guided Collaborative Training for Pixel-wise Semi-Supervised Learning](https://mlsanity.com/paper/2008.05258/) (2020)
- [Perturbed and Strict Mean Teachers for Semi-supervised Semantic Segmentation](https://mlsanity.com/paper/2111.12903/) (2021)
- [Self-supervised learning methods and applications in medical imaging analysis: A survey](https://mlsanity.com/paper/2109.08685/) (2021)
- [Learning with Limited Annotations: A Survey on Deep Semi-Supervised Learning for Medical Image Segmentation](https://mlsanity.com/paper/2207.14191/) (2022)
- [Deep Learning COVID-19 Features on CXR using Limited Training Data Sets](https://mlsanity.com/paper/2004.05758/) (2020)
- [Triple Generative Adversarial Nets](https://mlsanity.com/paper/1703.02291/) (2017)
- [Improving the Improved Training of Wasserstein GANs: A Consistency Term and Its Dual Effect](https://mlsanity.com/paper/1803.01541/) (2018)
- [XLSor: A Robust and Accurate Lung Segmentor on Chest X-Rays Using Criss-Cross Attention and Customized Radiorealistic Abnormalities Generation](https://mlsanity.com/paper/1904.09229/) (2019)
- [Duo-SegNet: Adversarial Dual-Views for Semi-Supervised Medical Image Segmentation](https://mlsanity.com/paper/2108.11154/) (2021)
- [Prediction of final infarct volume from native CT perfusion and treatment parameters using deep learning](https://mlsanity.com/paper/1812.02496/) (2018)
- [An Embarrassingly Simple Consistency Regularization Method for Semi-Supervised Medical Image Segmentation](https://mlsanity.com/paper/2202.00677/) (2022)

## Built on by (most cited first, 1 of 1)

- [Robust semi-supervised segmentation with timestep ensembling diffusion models](https://mlsanity.com/paper/2311.07421/) (2023)

## Abstract (arXiv)

Image segmentation is important in medical imaging, providing valuable, quantitative information for clinical decision-making in diagnosis, therapy, and intervention. The state-of-the-art in automated segmentation remains supervised learning, employing discriminative models such as U-Net. However, training these models requires access to large amounts of manually labelled data which is often difficult to obtain in real medical applications. In such settings, semi-supervised learning (SSL) attempts to leverage the abundance of unlabelled data to obtain more robust and reliable models. Recently, generative models have been proposed for semantic segmentation, as they make an attractive choice for SSL. Their ability to capture the joint distribution over input images and output label maps provides a natural way to incorporate information from unlabelled images. This paper analyses whether deep generative models such as the SemanticGAN are truly viable alternatives to tackle challenging medical image segmentation problems. To that end, we thoroughly evaluate the segmentation performance, robustness, and potential subgroup disparities of discriminative and generative segmentation methods when applied to large-scale, publicly available chest X-ray datasets.
