# Automated analysis of diabetic retinopathy using vessel segmentation maps as inductive bias

arXiv: https://arxiv.org/abs/2210.16053 · HTML: https://mlsanity.com/paper/2210.16053/

## Key facts

- No citing papers in the map yet (data through 14 Oct 2026).
- Builds on 12 of its 21 references that are in the map.
- First posted on arXiv 28 Oct 2022.

## Builds on (most cited first, 12 of 12)

- [Deep Residual Learning for Image Recognition](https://mlsanity.com/paper/1512.03385/) (2015)
- [U-Net: Convolutional Networks for Biomedical Image Segmentation](https://mlsanity.com/paper/1505.04597/) (2015)
- [EfficientNet: Rethinking Model Scaling for Convolutional Neural Networks](https://mlsanity.com/paper/1905.11946/) (2019)
- [3D U-Net: Learning Dense Volumetric Segmentation from Sparse Annotation](https://mlsanity.com/paper/1606.06650/) (2016)
- [Transfusion: Understanding Transfer Learning for Medical Imaging](https://mlsanity.com/paper/1902.07208/) (2019)
- [clDice -- A Novel Topology-Preserving Loss Function for Tubular Structure Segmentation](https://mlsanity.com/paper/2003.07311/) (2020)
- [ROSE: A Retinal OCT-Angiography Vessel Segmentation Dataset and New Model](https://mlsanity.com/paper/2007.05201/) (2020)
- [Red-GAN: Attacking class imbalance via conditioned generation. Yet another perspective on medical image synthesis for skin lesion dermoscopy and brain tumor MRI](https://mlsanity.com/paper/2004.10734/) (2020)
- [Physiology-based simulation of the retinal vasculature enables annotation-free segmentation of OCT angiographs](https://mlsanity.com/paper/2207.11102/) (2022)
- [METGAN: Generative Tumour Inpainting and Modality Synthesis in Light Sheet Microscopy](https://mlsanity.com/paper/2104.10993/) (2021)
- [Whole Brain Vessel Graphs: A Dataset and Benchmark for Graph Learning and Neuroscience (VesselGraph)](https://mlsanity.com/paper/2108.13233/) (2021)
- [A distance-based loss for smooth and continuous skin layer segmentation in optoacoustic images](https://mlsanity.com/paper/2007.05324/) (2020)

## Abstract (arXiv)

Recent studies suggest that early stages of diabetic retinopathy (DR) can be diagnosed by monitoring vascular changes in the deep vascular complex. In this work, we investigate a novel method for automated DR grading based on optical coherence tomography angiography (OCTA) images. Our work combines OCTA scans with their vessel segmentations, which then serve as inputs to task specific networks for lesion segmentation, image quality assessment and DR grading. For this, we generate synthetic OCTA images to train a segmentation network that can be directly applied on real OCTA data. We test our approach on MICCAI 2022's DR analysis challenge (DRAC). In our experiments, the proposed method performs equally well as the baseline model.