# HeartSpot: Privatized and Explainable Data Compression for Cardiomegaly Detection

arXiv: https://arxiv.org/abs/2210.02241 · HTML: https://mlsanity.com/paper/2210.02241/

## Key facts

- Cited by 2 papers in the map (data through 14 Oct 2026).
- Builds on 5 of its 9 references that are in the map.
- First posted on arXiv 5 Oct 2022.

## Builds on (most cited first, 5 of 5)

- [Densely Connected Convolutional Networks](https://mlsanity.com/paper/1608.06993/) (2016)
- [Learning Important Features Through Propagating Activation Differences](https://mlsanity.com/paper/1704.02685/) (2017)
- [CheXpert: A Large Chest Radiograph Dataset with Uncertainty Labels and Expert Comparison](https://mlsanity.com/paper/1901.07031/) (2019)
- [Captum: A unified and generic model interpretability library for PyTorch](https://mlsanity.com/paper/2009.07896/) (2020)
- [Comparing Different Deep Learning Architectures for Classification of Chest Radiographs](https://mlsanity.com/paper/2002.08991/) (2020)

## Built on by (most cited first, 2 of 2)

- [Privacy Risks and Preservation Methods in Explainable Artificial Intelligence: A Scoping Review](https://mlsanity.com/paper/2505.02828/) (2025)
- [Towards integration of Privacy Enhancing Technologies in Explainable Artificial Intelligence](https://mlsanity.com/paper/2507.04528/) (2025)

## Abstract (arXiv)

Advances in data-driven deep learning for chest X-ray image analysis underscore the need for explainability, privacy, large datasets and significant computational resources. We frame privacy and explainability as a lossy single-image compression problem to reduce both computational and data requirements without training. For Cardiomegaly detection in chest X-ray images, we propose HeartSpot and four spatial bias priors. HeartSpot priors define how to sample pixels based on domain knowledge from medical literature and from machines. HeartSpot privatizes chest X-ray images by discarding up to 97% of pixels, such as those that reveal the shape of the thoracic cage, bones, small lesions and other sensitive features. HeartSpot priors are ante-hoc explainable and give a human-interpretable image of the preserved spatial features that clearly outlines the heart. HeartSpot offers strong compression, with up to 32x fewer pixels and 11x smaller filesize. Cardiomegaly detectors using HeartSpot are up to 9x faster to train or at least as accurate (up to +.01 AUC ROC) when compared to a baseline DenseNet121. HeartSpot is post-hoc explainable by re-using existing attribution methods without requiring access to the original non-privatized image. In summary, HeartSpot improves speed and accuracy, reduces image size, improves privacy and ensures explainability. Source code: https://www.github.com/adgaudio/HeartSpot