# RL-MD: A Novel Reinforcement Learning Approach for DNA Motif Discovery

arXiv: https://arxiv.org/abs/2209.15181 · HTML: https://mlsanity.com/paper/2209.15181/

## Key facts

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- First posted on arXiv 30 Sep 2022.

## Abstract (arXiv)

The extraction of sequence patterns from a collection of functionally linked unlabeled DNA sequences is known as DNA motif discovery, and it is a key task in computational biology. Several deep learning-based techniques have recently been introduced to address this issue. However, these algorithms can not be used in real-world situations because of the need for labeled data. Here, we presented RL-MD, a novel reinforcement learning based approach for DNA motif discovery task. RL-MD takes unlabelled data as input, employs a relative information-based method to evaluate each proposed motif, and utilizes these continuous evaluation results as the reward. The experiments show that RL-MD can identify high-quality motifs in real-world data.