# Metal Inpainting in CBCT Projections Using Score-based Generative Model

arXiv: https://arxiv.org/abs/2209.09733 · HTML: https://mlsanity.com/paper/2209.09733/

## Key facts

- Cited by 7 papers in the map (data through 14 Oct 2026).
- Placed in Medical imaging and segmentation, one of 14 directions in Diffusion models.
- Builds on 10 of its 21 references that are in the map.
- First posted on arXiv 20 Sep 2022.

## Placed in

- Diffusion models / [Medical imaging and segmentation](https://mlsanity.com/diffusion/medical-imaging-and-segmentation/)

## Builds on (most cited first, 10 of 10)

- [Adam: A Method for Stochastic Optimization](https://mlsanity.com/paper/1412.6980/) (2014)
- [Denoising Diffusion Probabilistic Models](https://mlsanity.com/paper/2006.11239/) (2020)
- [Score-Based Generative Modeling through Stochastic Differential Equations](https://mlsanity.com/paper/2011.13456/) (2020)
- [Diffusion Models Beat GANs on Image Synthesis](https://mlsanity.com/paper/2105.05233/) (2021)
- [Fourier Features Let Networks Learn High Frequency Functions in Low Dimensional Domains](https://mlsanity.com/paper/2006.10739/) (2020)
- [RePaint: Inpainting using Denoising Diffusion Probabilistic Models](https://mlsanity.com/paper/2201.09865/) (2022)
- [Solving Inverse Problems in Medical Imaging with Score-Based Generative Models](https://mlsanity.com/paper/2111.08005/) (2021)
- [Score-based diffusion models for accelerated MRI](https://mlsanity.com/paper/2110.05243/) (2021)
- [Generative Mask Pyramid Network for CT/CBCT Metal Artifact Reduction with Joint Projection-Sinogram Correction](https://mlsanity.com/paper/1907.00294/) (2019)
- [DAN-Net: Dual-Domain Adaptive-Scaling Non-local Network for CT Metal Artifact Reduction](https://mlsanity.com/paper/2102.08003/) (2021)

## Built on by (most cited first, 7 of 7)

- [An Overview of Diffusion Models: Applications, Guided Generation, Statistical Rates and Optimization](https://mlsanity.com/paper/2404.07771/) (2024)
- [Unveil Conditional Diffusion Models with Classifier-free Guidance: A Sharp Statistical Theory](https://mlsanity.com/paper/2403.11968/) (2024)
- [Diffusion Models in Bioinformatics: A New Wave of Deep Learning Revolution in Action](https://mlsanity.com/paper/2302.10907/) (2023)
- [Diffusion Model Quantization: A Review](https://mlsanity.com/paper/2505.05215/) (2025)
- [Segmentation-Guided Knee Radiograph Generation using Conditional Diffusion Models](https://mlsanity.com/paper/2404.03541/) (2024)
- [3D CBCT Artefact Removal Using Perpendicular Score-Based Diffusion Models](https://mlsanity.com/paper/2603.06300/) (2026)
- [Diffusion Models in Medical Image Inpainting: Challenges, Solution Taxonomy, and Future Directions](https://mlsanity.com/paper/2607.21904/) (2026)

## Abstract (arXiv)

During orthopaedic surgery, the inserting of metallic implants or screws are often performed under mobile C-arm systems. Due to the high attenuation of metals, severe metal artifacts occur in 3D reconstructions, which degrade the image quality greatly. To reduce the artifacts, many metal artifact reduction algorithms have been developed and metal inpainting in projection domain is an essential step. In this work, a score-based generative model is trained on simulated knee projections and the inpainted image is obtained by removing the noise in conditional resampling process. The result implies that the inpainted images by score-based generative model have more detailed information and achieve the lowest mean absolute error and the highest peak-signal-to-noise-ratio compared with interpolation and CNN based method. Besides, the score-based model can also recover projections with big circlar and rectangular masks, showing its generalization in inpainting task.