# Noise transfer for unsupervised domain adaptation of retinal OCT images

arXiv: https://arxiv.org/abs/2209.08097 · HTML: https://mlsanity.com/paper/2209.08097/

## Key facts

- Cited by 6 papers in the map (data through 14 Oct 2026).
- Builds on 9 of its 30 references that are in the map.
- First posted on arXiv 16 Sep 2022.

## Builds on (most cited first, 9 of 9)

- [Deep Residual Learning for Image Recognition](https://mlsanity.com/paper/1512.03385/) (2015)
- [UMAP: Uniform Manifold Approximation and Projection for Dimension Reduction](https://mlsanity.com/paper/1802.03426/) (2018)
- [UNet++: Redesigning Skip Connections to Exploit Multiscale Features in Image Segmentation](https://mlsanity.com/paper/1912.05074/) (2019)
- [FDA: Fourier Domain Adaptation for Semantic Segmentation](https://mlsanity.com/paper/2004.05498/) (2020)
- [Confidence Regularized Self-Training](https://mlsanity.com/paper/1908.09822/) (2019)
- [Domain Adaptation for Medical Image Analysis: A Survey](https://mlsanity.com/paper/2102.09508/) (2021)
- [Phase Consistent Ecological Domain Adaptation](https://mlsanity.com/paper/2004.04923/) (2020)
- [Noise as Domain Shift: Denoising Medical Images by Unpaired Image Translation](https://mlsanity.com/paper/1910.02702/) (2019)
- [OCT-GAN: Single Step Shadow and Noise Removal from Optical Coherence Tomography Images of the Human Optic Nerve Head](https://mlsanity.com/paper/2010.11698/) (2020)

## Built on by (most cited first, 6 of 6)

- [Reverse Engineering Breast MRIs: Predicting Acquisition Parameters Directly from Images](https://mlsanity.com/paper/2303.04911/) (2023)
- [Navigating Distribution Shifts in Medical Image Analysis: A Survey](https://mlsanity.com/paper/2411.05824/) (2024)
- [Joint semi-supervised and contrastive learning enables domain generalization and multi-domain segmentation](https://mlsanity.com/paper/2405.05336/) (2024)
- [Anatomical Conditioning for Contrastive Unpaired Image-to-Image Translation of Optical Coherence Tomography Images](https://mlsanity.com/paper/2404.05409/) (2024)
- [nnUNet RASPP for Retinal OCT Fluid Detection, Segmentation and Generalisation over Variations of Data Sources](https://mlsanity.com/paper/2302.13195/) (2023)
- [Exploiting Intermediate Reconstructions in Optical Coherence Tomography for Test-Time Adaption of Medical Image Segmentation](https://mlsanity.com/paper/2603.05041/) (2026)

## Abstract (arXiv)

Optical coherence tomography (OCT) imaging from different camera devices causes challenging domain shifts and can cause a severe drop in accuracy for machine learning models. In this work, we introduce a minimal noise adaptation method based on a singular value decomposition (SVDNA) to overcome the domain gap between target domains from three different device manufacturers in retinal OCT imaging. Our method utilizes the difference in noise structure to successfully bridge the domain gap between different OCT devices and transfer the style from unlabeled target domain images to source images for which manual annotations are available. We demonstrate how this method, despite its simplicity, compares or even outperforms state-of-the-art unsupervised domain adaptation methods for semantic segmentation on a public OCT dataset. SVDNA can be integrated with just a few lines of code into the augmentation pipeline of any network which is in contrast to many state-of-the-art domain adaptation methods which often need to change the underlying model architecture or train a separate style transfer model. The full code implementation for SVDNA is available at https://github.com/ValentinKoch/SVDNA.
