# HarDNet-DFUS: An Enhanced Harmonically-Connected Network for Diabetic Foot Ulcer Image Segmentation and Colonoscopy Polyp Segmentation

arXiv: https://arxiv.org/abs/2209.07313 · HTML: https://mlsanity.com/paper/2209.07313/

## Key facts

- Cited by 6 papers in the map (data through 14 Oct 2026).
- Builds on 21 of its 25 references that are in the map.
- First posted on arXiv 15 Sep 2022.

## Builds on (most cited first, 21 of 21)

- [U-Net: Convolutional Networks for Biomedical Image Segmentation](https://mlsanity.com/paper/1505.04597/) (2015)
- [Squeeze-and-Excitation Networks](https://mlsanity.com/paper/1709.01507/) (2017)
- [SegFormer: Simple and Efficient Design for Semantic Segmentation with Transformers](https://mlsanity.com/paper/2105.15203/) (2021)
- [UNet++: A Nested U-Net Architecture for Medical Image Segmentation](https://mlsanity.com/paper/1807.10165/) (2018)
- [MLP-Mixer: An all-MLP Architecture for Vision](https://mlsanity.com/paper/2105.01601/) (2021)
- [ShuffleNet V2: Practical Guidelines for Efficient CNN Architecture Design](https://mlsanity.com/paper/1807.11164/) (2018)
- [Spatial Pyramid Pooling in Deep Convolutional Networks for Visual Recognition](https://mlsanity.com/paper/1406.4729/) (2014)
- [Kvasir-SEG: A Segmented Polyp Dataset](https://mlsanity.com/paper/1911.07069/) (2019)
- [CSPNet: A New Backbone that can Enhance Learning Capability of CNN](https://mlsanity.com/paper/1911.11929/) (2019)
- [A Benchmark for Endoluminal Scene Segmentation of Colonoscopy Images](https://mlsanity.com/paper/1612.00799/) (2016)
- [ResUNet++: An Advanced Architecture for Medical Image Segmentation](https://mlsanity.com/paper/1911.07067/) (2019)
- [F3Net: Fusion, Feedback and Focus for Salient Object Detection](https://mlsanity.com/paper/1911.11445/) (2019)
- [DoubleU-Net: A Deep Convolutional Neural Network for Medical Image Segmentation](https://mlsanity.com/paper/2006.04868/) (2020)
- [HarDNet: A Low Memory Traffic Network](https://mlsanity.com/paper/1909.00948/) (2019)
- [HarDNet-MSEG: A Simple Encoder-Decoder Polyp Segmentation Neural Network that Achieves over 0.9 Mean Dice and 86 FPS](https://mlsanity.com/paper/2101.07172/) (2021)
- [Lawin Transformer: Improving Semantic Segmentation Transformer with Multi-Scale Representations via Large Window Attention](https://mlsanity.com/paper/2201.01615/) (2022)
- [Recognition of Ischaemia and Infection in Diabetic Foot Ulcers: Dataset and Techniques](https://mlsanity.com/paper/1908.05317/) (2019)
- [Translating Clinical Delineation of Diabetic Foot Ulcers into Machine Interpretable Segmentation](https://mlsanity.com/paper/2204.11618/) (2022)
- [DFUNet: Convolutional Neural Networks for Diabetic Foot Ulcer Classification](https://mlsanity.com/paper/1711.10448/) (2017)
- [Analysis Towards Classification of Infection and Ischaemia of Diabetic Foot Ulcers](https://mlsanity.com/paper/2104.03068/) (2021)
- [DFUC2020: Analysis Towards Diabetic Foot Ulcer Detection](https://mlsanity.com/paper/2004.11853/) (2020)

## Built on by (most cited first, 6 of 6)

- [Using DUCK-Net for Polyp Image Segmentation](https://mlsanity.com/paper/2311.02239/) (2023)
- [A Survey on Deep Learning for Polyp Segmentation: Techniques, Challenges and Future Trends](https://mlsanity.com/paper/2311.18373/) (2023)
- [An Enhanced Harmonic Densely Connected Hybrid Transformer Network Architecture for Chronic Wound Segmentation Utilising Multi-Colour Space Tensor Merging](https://mlsanity.com/paper/2410.03359/) (2024)
- [Polyp segmentation in colonoscopy images using DeepLabV3++](https://mlsanity.com/paper/2407.19327/) (2024)
- [CLFSeg: A Fuzzy-Logic based Solution for Boundary Clarity and Uncertainty Reduction in Medical Image Segmentation](https://mlsanity.com/paper/2510.24202/) (2025)
- [Contour Refinement using Discrete Diffusion in Low Data Regime](https://mlsanity.com/paper/2602.05880/) (2026)

## Abstract (arXiv)

We present a neural network architecture for medical image segmentation of diabetic foot ulcers and colonoscopy polyps. Diabetic foot ulcers are caused by neuropathic and vascular complications of diabetes mellitus. In order to provide a proper diagnosis and treatment, wound care professionals need to extract accurate morphological features from the foot wounds. Using computer-aided systems is a promising approach to extract related morphological features and segment the lesions. We propose a convolution neural network called HarDNet-DFUS by enhancing the backbone and replacing the decoder of HarDNet-MSEG, which was SOTA for colonoscopy polyp segmentation in 2021. For the MICCAI 2022 Diabetic Foot Ulcer Segmentation Challenge (DFUC2022), we train HarDNet-DFUS using the DFUC2022 dataset and increase its robustness by means of five-fold cross validation, Test Time Augmentation, etc. In the validation phase of DFUC2022, HarDNet-DFUS achieved 0.7063 mean dice and was ranked third among all participants. In the final testing phase of DFUC2022, it achieved 0.7287 mean dice and was the first place winner. HarDNet-DFUS also deliver excellent performance for the colonoscopy polyp segmentation task. It achieves 0.924 mean Dice on the famous Kvasir dataset, an improvement of 1.2% over the original HarDNet-MSEG. The codes are available on https://github.com/kytimmylai/DFUC2022 (for Diabetic Foot Ulcers Segmentation) and https://github.com/YuWenLo/HarDNet-DFUS (for Colonoscopy Polyp Segmentation).