# Visual Interpretable and Explainable Deep Learning Models for Brain Tumor MRI and COVID-19 Chest X-ray Images

arXiv: https://arxiv.org/abs/2208.00953 · HTML: https://mlsanity.com/paper/2208.00953/

## Key facts

- No citing papers in the map yet (data through 14 Oct 2026).
- Builds on 29 of its 53 references that are in the map.
- First posted on arXiv 1 Aug 2022.

## Builds on (most cited first, 29 of 29)

- [Deep Residual Learning for Image Recognition](https://mlsanity.com/paper/1512.03385/) (2015)
- [Very Deep Convolutional Networks for Large-Scale Image Recognition](https://mlsanity.com/paper/1409.1556/) (2014)
- [ImageNet Large Scale Visual Recognition Challenge](https://mlsanity.com/paper/1409.0575/) (2014)
- [Grad-CAM: Visual Explanations from Deep Networks via Gradient-based Localization](https://mlsanity.com/paper/1610.02391/) (2016)
- [Densely Connected Convolutional Networks](https://mlsanity.com/paper/1608.06993/) (2016)
- [EfficientNet: Rethinking Model Scaling for Convolutional Neural Networks](https://mlsanity.com/paper/1905.11946/) (2019)
- [Model-Agnostic Meta-Learning for Fast Adaptation of Deep Networks](https://mlsanity.com/paper/1703.03400/) (2017)
- [Going Deeper with Convolutions](https://mlsanity.com/paper/1409.4842/) (2014)
- [Axiomatic Attribution for Deep Networks](https://mlsanity.com/paper/1703.01365/) (2017)
- [Deep Inside Convolutional Networks: Visualising Image Classification Models and Saliency Maps](https://mlsanity.com/paper/1312.6034/) (2013)
- [Xception: Deep Learning with Depthwise Separable Convolutions](https://mlsanity.com/paper/1610.02357/) (2016)
- [Inception-v4, Inception-ResNet and the Impact of Residual Connections on Learning](https://mlsanity.com/paper/1602.07261/) (2016)
- [ImageNet-trained CNNs are biased towards texture; increasing shape bias improves accuracy and robustness](https://mlsanity.com/paper/1811.12231/) (2018)
- [A Survey on Deep Learning in Medical Image Analysis](https://mlsanity.com/paper/1702.05747/) (2017)
- [Concept Bottleneck Models](https://mlsanity.com/paper/2007.04612/) (2020)
- [Network Dissection: Quantifying Interpretability of Deep Visual Representations](https://mlsanity.com/paper/1704.05796/) (2017)
- [Dynamic Routing Between Capsules](https://mlsanity.com/paper/1710.09829/) (2017)
- [Understanding the Effective Receptive Field in Deep Convolutional Neural Networks](https://mlsanity.com/paper/1701.04128/) (2017)
- [Deep Learning for Case-Based Reasoning through Prototypes: A Neural Network that Explains Its Predictions](https://mlsanity.com/paper/1710.04806/) (2017)
- [Can AI help in screening Viral and COVID-19 pneumonia?](https://mlsanity.com/paper/2003.13145/) (2020)
- [XRAI: Better Attributions Through Regions](https://mlsanity.com/paper/1906.02825/) (2019)
- [Guided Integrated Gradients: An Adaptive Path Method for Removing Noise](https://mlsanity.com/paper/2106.09788/) (2021)
- [Transparency of Deep Neural Networks for Medical Image Analysis: A Review of Interpretability Methods](https://mlsanity.com/paper/2111.02398/) (2021)
- [XProtoNet: Diagnosis in Chest Radiography with Global and Local Explanations](https://mlsanity.com/paper/2103.10663/) (2021)
- [Visual Feature Attribution using Wasserstein GANs](https://mlsanity.com/paper/1711.08998/) (2017)
- [Using StyleGAN for Visual Interpretability of Deep Learning Models on Medical Images](https://mlsanity.com/paper/2101.07563/) (2021)
- [An Interpretable Deep Hierarchical Semantic Convolutional Neural Network for Lung Nodule Malignancy Classification](https://mlsanity.com/paper/1806.00712/) (2018)
- [ICAM: Interpretable Classification via Disentangled Representations and Feature Attribution Mapping](https://mlsanity.com/paper/2006.08287/) (2020)
- [Domain aware medical image classifier interpretation by counterfactual impact analysis](https://mlsanity.com/paper/2007.06312/) (2020)

## Abstract (arXiv)

Deep learning shows promise for medical image analysis but lacks interpretability, hindering adoption in healthcare. Attribution techniques that explain model reasoning may increase trust in deep learning among clinical stakeholders. This paper aimed to evaluate attribution methods for illuminating how deep neural networks analyze medical images. Using adaptive path-based gradient integration, we attributed predictions from brain tumor MRI and COVID-19 chest X-ray datasets made by recent deep convolutional neural network models. The technique highlighted possible biomarkers, exposed model biases, and offered insights into the links between input and prediction. Our analysis demonstrates the method's ability to elucidate model reasoning on these datasets. The resulting attributions show promise for improving deep learning transparency for domain experts by revealing the rationale behind predictions. This study advances model interpretability to increase trust in deep learning among healthcare stakeholders.