# Personalizing Federated Medical Image Segmentation via Local Calibration

arXiv: https://arxiv.org/abs/2207.04655 · HTML: https://mlsanity.com/paper/2207.04655/

## Key facts

- Cited by 29 papers in the map (data through 14 Oct 2026).
- Builds on 29 of its 41 references that are in the map.
- First posted on arXiv 11 Jul 2022.

## Builds on (most cited first, 29 of 29)

- [U-Net: Convolutional Networks for Biomedical Image Segmentation](https://mlsanity.com/paper/1505.04597/) (2015)
- [Communication-Efficient Learning of Deep Networks from Decentralized Data](https://mlsanity.com/paper/1602.05629/) (2016)
- [Advances and Open Problems in Federated Learning](https://mlsanity.com/paper/1912.04977/) (2019)
- [Federated Learning: Strategies for Improving Communication Efficiency](https://mlsanity.com/paper/1610.05492/) (2016)
- [The Future of Digital Health with Federated Learning](https://mlsanity.com/paper/2003.08119/) (2020)
- [Kvasir-SEG: A Segmented Polyp Dataset](https://mlsanity.com/paper/1911.07069/) (2019)
- [FedBN: Federated Learning on Non-IID Features via Local Batch Normalization](https://mlsanity.com/paper/2102.07623/) (2021)
- [Exploiting Shared Representations for Personalized Federated Learning](https://mlsanity.com/paper/2102.07078/) (2021)
- [Towards Personalized Federated Learning](https://mlsanity.com/paper/2103.00710/) (2021)
- [PraNet: Parallel Reverse Attention Network for Polyp Segmentation](https://mlsanity.com/paper/2006.11392/) (2020)
- [FedPAQ: A Communication-Efficient Federated Learning Method with Periodic Averaging and Quantization](https://mlsanity.com/paper/1909.13014/) (2019)
- [FedDG: Federated Domain Generalization on Medical Image Segmentation via Episodic Learning in Continuous Frequency Space](https://mlsanity.com/paper/2103.06030/) (2021)
- [REFUGE Challenge: A Unified Framework for Evaluating Automated Methods for Glaucoma Assessment from Fundus Photographs](https://mlsanity.com/paper/1910.03667/) (2019)
- [Federated Multi-Task Learning under a Mixture of Distributions](https://mlsanity.com/paper/2108.10252/) (2021)
- [Privacy-preserving Federated Brain Tumour Segmentation](https://mlsanity.com/paper/1910.00962/) (2019)
- [Polyp-PVT: Polyp Segmentation with Pyramid Vision Transformers](https://mlsanity.com/paper/2108.06932/) (2021)
- [Multi-Institutional Deep Learning Modeling Without Sharing Patient Data: A Feasibility Study on Brain Tumor Segmentation](https://mlsanity.com/paper/1810.04304/) (2018)
- [Federated Evaluation of On-device Personalization](https://mlsanity.com/paper/1910.10252/) (2019)
- [Survey of Personalization Techniques for Federated Learning](https://mlsanity.com/paper/2003.08673/) (2020)
- [Salvaging Federated Learning by Local Adaptation](https://mlsanity.com/paper/2002.04758/) (2020)
- [MS-Net: Multi-Site Network for Improving Prostate Segmentation with Heterogeneous MRI Data](https://mlsanity.com/paper/2002.03366/) (2020)
- [Siloed Federated Learning for Multi-Centric Histopathology Datasets](https://mlsanity.com/paper/2008.07424/) (2020)
- [SA-Net: Shuffle Attention for Deep Convolutional Neural Networks](https://mlsanity.com/paper/2102.00240/) (2021)
- [Federated Learning in Distributed Medical Databases: Meta-Analysis of Large-Scale Subcortical Brain Data](https://mlsanity.com/paper/1810.08553/) (2018)
- [Federated Learning with Domain Generalization](https://mlsanity.com/paper/2111.10487/) (2021)
- [Federated Heavy Hitters Discovery with Differential Privacy](https://mlsanity.com/paper/1902.08534/) (2019)
- [Personalized Retrogress-Resilient Framework for Real-World Medical Federated Learning](https://mlsanity.com/paper/2110.00394/) (2021)
- [Fed-Sim: Federated Simulation for Medical Imaging](https://mlsanity.com/paper/2009.00668/) (2020)
- [Utilizing Transfer Learning and a Customized Loss Function for Optic Disc Segmentation from Retinal Images](https://mlsanity.com/paper/2010.00583/) (2020)

## Built on by (most cited first, 29 of 29)

- [Think Twice Before Selection: Federated Evidential Active Learning for Medical Image Analysis with Domain Shifts](https://mlsanity.com/paper/2312.02567/) (2023)
- [FedA3I: Annotation Quality-Aware Aggregation for Federated Medical Image Segmentation against Heterogeneous Annotation Noise](https://mlsanity.com/paper/2312.12838/) (2023)
- [MH-pFLID: Model Heterogeneous personalized Federated Learning via Injection and Distillation for Medical Data Analysis](https://mlsanity.com/paper/2405.06822/) (2024)
- [dFLMoE: Decentralized Federated Learning via Mixture of Experts for Medical Data Analysis](https://mlsanity.com/paper/2503.10412/) (2025)
- [FedLPPA: Learning Personalized Prompt and Aggregation for Federated Weakly-supervised Medical Image Segmentation](https://mlsanity.com/paper/2402.17502/) (2024)
- [Navigating Distribution Shifts in Medical Image Analysis: A Survey](https://mlsanity.com/paper/2411.05824/) (2024)
- [Unifying and Personalizing Weakly-supervised Federated Medical Image Segmentation via Adaptive Representation and Aggregation](https://mlsanity.com/paper/2304.05635/) (2023)
- [MH-pFLGB: Model Heterogeneous personalized Federated Learning via Global Bypass for Medical Image Analysis](https://mlsanity.com/paper/2407.00474/) (2024)
- [Personalizing Federated Instrument Segmentation with Visual Trait Priors in Robotic Surgery](https://mlsanity.com/paper/2408.03208/) (2024)
- [Divide, Conquer and Unite: Hierarchical Style-Recalibrated Prototype Alignment for Federated Medical Segmentation](https://mlsanity.com/paper/2511.10945/) (2025)
- [Federated Modality-specific Encoders and Partially Personalized Fusion Decoder for Multimodal Brain Tumor Segmentation](https://mlsanity.com/paper/2603.04887/) (2026)
- [Cyclical Weight Consolidation: Towards Solving Catastrophic Forgetting in Serial Federated Learning](https://mlsanity.com/paper/2405.10647/) (2024)
- [FedIA: Federated Medical Image Segmentation with Heterogeneous Annotation Completeness](https://mlsanity.com/paper/2407.02280/) (2024)
- [A New Perspective to Boost Performance Fairness for Medical Federated Learning](https://mlsanity.com/paper/2410.19765/) (2024)
- [Medical Federated Model with Mixture of Personalized and Sharing Components](https://mlsanity.com/paper/2306.14483/) (2023)
- [FovEx: Human-Inspired Explanations for Vision Transformers and Convolutional Neural Networks](https://mlsanity.com/paper/2408.02123/) (2024)
- [Federated Self-Supervised Learning for One-Shot Cross-Modal and Cross-Imaging Technique Segmentation](https://mlsanity.com/paper/2503.23507/) (2025)
- [Federated Black-Box Adaptation for Semantic Segmentation](https://mlsanity.com/paper/2410.24181/) (2024)
- [FedSCA: Federated Tuning with Similarity-guided Collaborative Aggregation for Heterogeneous Medical Image Segmentation](https://mlsanity.com/paper/2503.15390/) (2025)
- [Asynchronous Federated Continual Segmentation with Evolving Clients and Label Spaces](https://mlsanity.com/paper/2503.15414/) (2025)
- [CARE: Confidence-aware Ratio Estimation for Medical Biomarkers](https://mlsanity.com/paper/2505.19585/) (2025)
- [Adversarial Versus Federated: An Adversarial Learning based Multi-Modality Cross-Domain Federated Medical Segmentation](https://mlsanity.com/paper/2509.23907/) (2025)
- [Privacy-Aware Federated nnU-Net for ECG Page Digitization](https://mlsanity.com/paper/2510.22387/) (2025)
- [Personalized Federated Segmentation with Shared Feature Aggregation and Boundary-Focused Calibration](https://mlsanity.com/paper/2511.18847/) (2025)
- [FedEU: Evidential Uncertainty-Driven Federated Fine-Tuning of Vision Foundation Models for Remote Sensing Image Segmentation](https://mlsanity.com/paper/2603.07468/) (2026)
- [Federated Active Learning Under Extreme Non-IID and Global Class Imbalance](https://mlsanity.com/paper/2603.10341/) (2026)
- [UMEDA: Unified Multi-modal Efficient Data Fusion for Privacy-Preserving Graph Federated Learning via Spectral-Gated Attention and Diffusion-Based Operator Alignment](https://mlsanity.com/paper/2605.08288/) (2026)
- [FedASAP: Activation Statistics-driven Structured Adaptive Pruning for Efficient Personalized Federated Learning for Lesion Segmentation on brain MRI](https://mlsanity.com/paper/2609.19042/) (2026)
- [Decouple, Purify and Unite: Semantic-Structural Prototype Learning for Federated Medical Segmentation](https://mlsanity.com/paper/2610.04700/) (2026)

## Abstract (arXiv)

Medical image segmentation under federated learning (FL) is a promising direction by allowing multiple clinical sites to collaboratively learn a global model without centralizing datasets. However, using a single model to adapt to various data distributions from different sites is extremely challenging. Personalized FL tackles this issue by only utilizing partial model parameters shared from global server, while keeping the rest to adapt to its own data distribution in the local training of each site. However, most existing methods concentrate on the partial parameter splitting, while do not consider the textitinter-site in-consistencies during the local training, which in fact can facilitate the knowledge communication over sites to benefit the model learning for improving the local accuracy. In this paper, we propose a personalized federated framework with Local Calibration (LC-Fed), to leverage the inter-site in-consistencies in both textitfeature- and prediction- levels to boost the segmentation. Concretely, as each local site has its alternative attention on the various features, we first design the contrastive site embedding coupled with channel selection operation to calibrate the encoded features. Moreover, we propose to exploit the knowledge of prediction-level in-consistency to guide the personalized modeling on the ambiguous regions, e.g., anatomical boundaries. It is achieved by computing a disagreement-aware map to calibrate the prediction. Effectiveness of our method has been verified on three medical image segmentation tasks with different modalities, where our method consistently shows superior performance to the state-of-the-art personalized FL methods. Code is available at https://github.com/jcwang123/FedLC.