# Context-Aware Transformers For Spinal Cancer Detection and Radiological Grading

arXiv: https://arxiv.org/abs/2206.13173 · HTML: https://mlsanity.com/paper/2206.13173/

## Key facts

- Cited by 8 papers in the map (data through 14 Oct 2026).
- Builds on 9 of its 37 references that are in the map.
- First posted on arXiv 27 Jun 2022.

## Builds on (most cited first, 9 of 9)

- [Deep Residual Learning for Image Recognition](https://mlsanity.com/paper/1512.03385/) (2015)
- [End-to-End Object Detection with Transformers](https://mlsanity.com/paper/2005.12872/) (2020)
- [Frozen in Time: A Joint Video and Image Encoder for End-to-End Retrieval](https://mlsanity.com/paper/2104.00650/) (2021)
- [TrackFormer: Multi-Object Tracking with Transformers](https://mlsanity.com/paper/2101.02702/) (2021)
- [Multi-modal Transformer for Video Retrieval](https://mlsanity.com/paper/2007.10639/) (2020)
- [Self-Supervised Learning for Spinal MRIs](https://mlsanity.com/paper/1708.00367/) (2017)
- [A Convolutional Approach to Vertebrae Detection and Labelling in Whole Spine MRI](https://mlsanity.com/paper/2007.02606/) (2020)
- [SpineNetV2: Automated Detection, Labelling and Radiological Grading Of Clinical MR Scans](https://mlsanity.com/paper/2205.01683/) (2022)
- [The Ladder Algorithm: Finding Repetitive Structures in Medical Images by Induction](https://mlsanity.com/paper/2001.11284/) (2020)

## Built on by (most cited first, 8 of 8)

- [Counterfactual Explanations for Medical Image Classification and Regression using Diffusion Autoencoder](https://mlsanity.com/paper/2408.01571/) (2024)
- [UKBOB: One Billion MRI Labeled Masks for Generalizable 3D Medical Image Segmentation](https://mlsanity.com/paper/2504.06908/) (2025)
- [A Stronger Baseline For Automatic Pfirrmann Grading Of Lumbar Spine MRI Using Deep Learning](https://mlsanity.com/paper/2210.14597/) (2022)
- [Semantic Latent Space Regression of Diffusion Autoencoders for Vertebral Fracture Grading](https://mlsanity.com/paper/2303.12031/) (2023)
- [Transformer-based end-to-end classification of variable-length volumetric data](https://mlsanity.com/paper/2307.06666/) (2023)
- [Automated Spinal MRI Labelling from Reports Using a Large Language Model](https://mlsanity.com/paper/2410.17235/) (2024)
- [Rendering Novel Views of MRI Using 3D Gaussian Splatting](https://mlsanity.com/paper/2606.26236/) (2026)
- [Video-Text Temporal Localization via Multi-Scale Convolution and Dynamic Routing](https://mlsanity.com/paper/2607.05093/) (2026)

## Abstract (arXiv)

This paper proposes a novel transformer-based model architecture for medical imaging problems involving analysis of vertebrae. It considers two applications of such models in MR images: (a) detection of spinal metastases and the related conditions of vertebral fractures and metastatic cord compression, (b) radiological grading of common degenerative changes in intervertebral discs. Our contributions are as follows: (i) We propose a Spinal Context Transformer (SCT), a deep-learning architecture suited for the analysis of repeated anatomical structures in medical imaging such as vertebral bodies (VBs). Unlike previous related methods, SCT considers all VBs as viewed in all available image modalities together, making predictions for each based on context from the rest of the spinal column and all available imaging modalities. (ii) We apply the architecture to a novel and important task: detecting spinal metastases and the related conditions of cord compression and vertebral fractures/collapse from multi-series spinal MR scans. This is done using annotations extracted from free-text radiological reports as opposed to bespoke annotation. However, the resulting model shows strong agreement with vertebral-level bespoke radiologist annotations on the test set. (iii) We also apply SCT to an existing problem: radiological grading of inter-vertebral discs (IVDs) in lumbar MR scans for common degenerative changes.We show that by considering the context of vertebral bodies in the image, SCT improves the accuracy for several gradings compared to previously published model.
