# Multi-scale Super-resolution Magnetic Resonance Spectroscopic Imaging with Adjustable Sharpness

arXiv: https://arxiv.org/abs/2206.08984 · HTML: https://mlsanity.com/paper/2206.08984/

## Key facts

- Cited by 4 papers in the map (data through 14 Oct 2026).
- Builds on 17 of its 34 references that are in the map.
- First posted on arXiv 17 Jun 2022.

## Builds on (most cited first, 17 of 17)

- [Adam: A Method for Stochastic Optimization](https://mlsanity.com/paper/1412.6980/) (2014)
- [The Unreasonable Effectiveness of Deep Features as a Perceptual Metric](https://mlsanity.com/paper/1801.03924/) (2018)
- [Delving Deep into Rectifiers: Surpassing Human-Level Performance on ImageNet Classification](https://mlsanity.com/paper/1502.01852/) (2015)
- [Improved Techniques for Training GANs](https://mlsanity.com/paper/1606.03498/) (2016)
- [Improved Training of Wasserstein GANs](https://mlsanity.com/paper/1704.00028/) (2017)
- [Arbitrary Style Transfer in Real-time with Adaptive Instance Normalization](https://mlsanity.com/paper/1703.06868/) (2017)
- [HyperNetworks](https://mlsanity.com/paper/1609.09106/) (2016)
- [Deep Learning for Image Super-resolution: A Survey](https://mlsanity.com/paper/1902.06068/) (2019)
- [A Deep Cascade of Convolutional Neural Networks for Dynamic MR Image Reconstruction](https://mlsanity.com/paper/1704.02422/) (2017)
- [Meta-SR: A Magnification-Arbitrary Network for Super-Resolution](https://mlsanity.com/paper/1903.00875/) (2019)
- [Learning A Single Network for Scale-Arbitrary Super-Resolution](https://mlsanity.com/paper/2004.03791/) (2020)
- [Conditional Deformable Image Registration with Convolutional Neural Network](https://mlsanity.com/paper/2106.12673/) (2021)
- [A Unified Hyper-GAN Model for Unpaired Multi-contrast MR Image Translation](https://mlsanity.com/paper/2107.11945/) (2021)
- [Dense Multi-path U-Net for Ischemic Stroke Lesion Segmentation in Multiple Image Modalities](https://mlsanity.com/paper/1810.07003/) (2018)
- [Latent Filter Scaling for Multimodal Unsupervised Image-to-Image Translation](https://mlsanity.com/paper/1812.09877/) (2018)
- [Arbitrary Scale Super-Resolution for Brain MRI Images](https://mlsanity.com/paper/2004.02086/) (2020)
- [Invertible Sharpening Network for MRI Reconstruction Enhancement](https://mlsanity.com/paper/2206.02838/) (2022)

## Built on by (most cited first, 4 of 4)

- [Cross-Scale MAE: A Tale of Multi-Scale Exploitation in Remote Sensing](https://mlsanity.com/paper/2401.15855/) (2024)
- [Flow-based Visual Quality Enhancer for Super-resolution Magnetic Resonance Spectroscopic Imaging](https://mlsanity.com/paper/2207.10181/) (2022)
- [A Flow-based Truncated Denoising Diffusion Model for Super-resolution Magnetic Resonance Spectroscopic Imaging](https://mlsanity.com/paper/2410.19288/) (2024)
- [Towards Arbitrary-scale Histopathology Image Super-resolution: An Efficient Dual-branch Framework based on Implicit Self-texture Enhancement](https://mlsanity.com/paper/2304.04238/) (2023)

## Abstract (arXiv)

Magnetic Resonance Spectroscopic Imaging (MRSI) is a valuable tool for studying metabolic activities in the human body, but the current applications are limited to low spatial resolutions. The existing deep learning-based MRSI super-resolution methods require training a separate network for each upscaling factor, which is time-consuming and memory inefficient. We tackle this multi-scale super-resolution problem using a Filter Scaling strategy that modulates the convolution filters based on the upscaling factor, such that a single network can be used for various upscaling factors. Observing that each metabolite has distinct spatial characteristics, we also modulate the network based on the specific metabolite. Furthermore, our network is conditioned on the weight of adversarial loss so that the perceptual sharpness of the super-resolved metabolic maps can be adjusted within a single network. We incorporate these network conditionings using a novel Multi-Conditional Module. The experiments were carried out on a 1H-MRSI dataset from 15 high-grade glioma patients. Results indicate that the proposed network achieves the best performance among several multi-scale super-resolution methods and can provide super-resolved metabolic maps with adjustable sharpness.
