# Memory-efficient Segmentation of High-resolution Volumetric MicroCT Images

arXiv: https://arxiv.org/abs/2205.15941 · HTML: https://mlsanity.com/paper/2205.15941/

## Key facts

- Cited by 1 papers in the map (data through 14 Oct 2026).
- Builds on 19 of its 24 references that are in the map.
- First posted on arXiv 31 May 2022.

## Builds on (most cited first, 19 of 19)

- [Deep Residual Learning for Image Recognition](https://mlsanity.com/paper/1512.03385/) (2015)
- [U-Net: Convolutional Networks for Biomedical Image Segmentation](https://mlsanity.com/paper/1505.04597/) (2015)
- [V-Net: Fully Convolutional Neural Networks for Volumetric Medical Image Segmentation](https://mlsanity.com/paper/1606.04797/) (2016)
- [TransUNet: Transformers Make Strong Encoders for Medical Image Segmentation](https://mlsanity.com/paper/2102.04306/) (2021)
- [UNet++: A Nested U-Net Architecture for Medical Image Segmentation](https://mlsanity.com/paper/1807.10165/) (2018)
- [3D U-Net: Learning Dense Volumetric Segmentation from Sparse Annotation](https://mlsanity.com/paper/1606.06650/) (2016)
- [Attention U-Net: Learning Where to Look for the Pancreas](https://mlsanity.com/paper/1804.03999/) (2018)
- [UNETR: Transformers for 3D Medical Image Segmentation](https://mlsanity.com/paper/2103.10504/) (2021)
- [Generalised Dice overlap as a deep learning loss function for highly unbalanced segmentations](https://mlsanity.com/paper/1707.03237/) (2017)
- [Holistically-Nested Edge Detection](https://mlsanity.com/paper/1504.06375/) (2015)
- [Deeply-Supervised Nets](https://mlsanity.com/paper/1409.5185/) (2014)
- [CoTr: Efficiently Bridging CNN and Transformer for 3D Medical Image Segmentation](https://mlsanity.com/paper/2103.03024/) (2021)
- [Multi-Compound Transformer for Accurate Biomedical Image Segmentation](https://mlsanity.com/paper/2106.14385/) (2021)
- [Automatic 3D Cardiovascular MR Segmentation with Densely-Connected Volumetric ConvNets](https://mlsanity.com/paper/1708.00573/) (2017)
- [Deeply-Supervised CNN for Prostate Segmentation](https://mlsanity.com/paper/1703.07523/) (2017)
- [A multi-scale pyramid of 3D fully convolutional networks for abdominal multi-organ segmentation](https://mlsanity.com/paper/1806.02237/) (2018)
- [A Partially Reversible U-Net for Memory-Efficient Volumetric Image Segmentation](https://mlsanity.com/paper/1906.06148/) (2019)
- [OSS-Net: Memory Efficient High Resolution Semantic Segmentation of 3D Medical Data](https://mlsanity.com/paper/2110.10640/) (2021)
- [CU-Net: Cascaded U-Net with Loss Weighted Sampling for Brain Tumor Segmentation](https://mlsanity.com/paper/1907.07677/) (2019)

## Built on by (most cited first, 1 of 1)

- [Detail Consistent Stage-Wise Distillation for Efficient 3D MRI Segmentation](https://mlsanity.com/paper/2605.26382/) (2026)

## Abstract (arXiv)

In recent years, 3D convolutional neural networks have become the dominant approach for volumetric medical image segmentation. However, compared to their 2D counterparts, 3D networks introduce substantially more training parameters and higher requirement for the GPU memory. This has become a major limiting factor for designing and training 3D networks for high-resolution volumetric images. In this work, we propose a novel memory-efficient network architecture for 3D high-resolution image segmentation. The network incorporates both global and local features via a two-stage U-net-based cascaded framework and at the first stage, a memory-efficient U-net (meU-net) is developed. The features learnt at the two stages are connected via post-concatenation, which further improves the information flow. The proposed segmentation method is evaluated on an ultra high-resolution microCT dataset with typically 250 million voxels per volume. Experiments show that it outperforms state-of-the-art 3D segmentation methods in terms of both segmentation accuracy and memory efficiency.