# Cervical Glandular Cell Detection from Whole Slide Image with Out-Of-Distribution Data

arXiv: https://arxiv.org/abs/2205.14625 · HTML: https://mlsanity.com/paper/2205.14625/

## Key facts

- No citing papers in the map yet (data through 14 Oct 2026).
- Builds on 18 of its 40 references that are in the map.
- First posted on arXiv 29 May 2022.

## Builds on (most cited first, 18 of 18)

- [Deep Residual Learning for Image Recognition](https://mlsanity.com/paper/1512.03385/) (2015)
- [PyTorch: An Imperative Style, High-Performance Deep Learning Library](https://mlsanity.com/paper/1912.01703/) (2019)
- [Very Deep Convolutional Networks for Large-Scale Image Recognition](https://mlsanity.com/paper/1409.1556/) (2014)
- [Rethinking the Inception Architecture for Computer Vision](https://mlsanity.com/paper/1512.00567/) (2015)
- [Feature Pyramid Networks for Object Detection](https://mlsanity.com/paper/1612.03144/) (2016)
- [You Only Look Once: Unified, Real-Time Object Detection](https://mlsanity.com/paper/1506.02640/) (2015)
- [Going Deeper with Convolutions](https://mlsanity.com/paper/1409.4842/) (2014)
- [Fast R-CNN](https://mlsanity.com/paper/1504.08083/) (2015)
- [YOLOv3: An Incremental Improvement](https://mlsanity.com/paper/1804.02767/) (2018)
- [FCOS: Fully Convolutional One-Stage Object Detection](https://mlsanity.com/paper/1904.01355/) (2019)
- [Cascade R-CNN: Delving into High Quality Object Detection](https://mlsanity.com/paper/1712.00726/) (2017)
- [YOLOX: Exceeding YOLO Series in 2021](https://mlsanity.com/paper/2107.08430/) (2021)
- [Path Aggregation Network for Instance Segmentation](https://mlsanity.com/paper/1803.01534/) (2018)
- [DeepPap: Deep Convolutional Networks for Cervical Cell Classification](https://mlsanity.com/paper/1801.08616/) (2018)
- [Deep Learning for Computational Cytology: A Survey](https://mlsanity.com/paper/2202.05126/) (2022)
- [Fine-Grained Classification of Cervical Cells Using Morphological and Appearance Based Convolutional Neural Networks](https://mlsanity.com/paper/1810.06058/) (2018)
- [A Novel Automation-Assisted Cervical Cancer Reading Method Based on Convolutional Neural Network](https://mlsanity.com/paper/1912.06649/) (2019)
- [An Efficient Cervical Whole Slide Image Analysis Framework Based on Multi-scale Semantic and Location Deep Features](https://mlsanity.com/paper/2106.15113/) (2021)

## Abstract (arXiv)

Cervical glandular cell (GC) detection is a key step in computer-aided diagnosis for cervical adenocarcinomas screening. It is challenging to accurately recognize GCs in cervical smears in which squamous cells are the major. Widely existing Out-Of-Distribution (OOD) data in the entire smear leads decreasing reliability of machine learning system for GC detection. Although, the State-Of-The-Art (SOTA) deep learning model can outperform pathologists in preselected regions of interest, the mass False Positive (FP) prediction with high probability is still unsolved when facing such gigapixel whole slide image. This paper proposed a novel PolarNet based on the morphological prior knowledge of GC trying to solve the FP problem via a self-attention mechanism in eight-neighbor. It estimates the polar orientation of nucleus of GC. As a plugin module, PolarNet can guide the deep feature and predicted confidence of general object detection models. In experiments, we discovered that general models based on four different frameworks can reject FP in small image set and increase the mean of average precision (mAP) by 0.007~0.015 in average, where the highest exceeds the recent cervical cell detection model 0.037. By plugging PolarNet, the deployed C++ program improved by 8.8% on accuracy of top-20 GC detection from external WSIs, while sacrificing 14.4 s of computational time. Code is available in https://github.com/Chrisa142857/PolarNet-GCdet