# Assigning Species Information to Corresponding Genes by a Sequence Labeling Framework

arXiv: https://arxiv.org/abs/2205.03853 · HTML: https://mlsanity.com/paper/2205.03853/

## Key facts

- Cited by 3 papers in the map (data through 14 Oct 2026).
- Builds on 4 of its 27 references that are in the map.
- First posted on arXiv 8 May 2022.

## Builds on (most cited first, 4 of 4)

- [Adam: A Method for Stochastic Optimization](https://mlsanity.com/paper/1412.6980/) (2014)
- [BioBERT: a pre-trained biomedical language representation model for biomedical text mining](https://mlsanity.com/paper/1901.08746/) (2019)
- [Domain-Specific Language Model Pretraining for Biomedical Natural Language Processing](https://mlsanity.com/paper/2007.15779/) (2020)
- [HunFlair: An Easy-to-Use Tool for State-of-the-Art Biomedical Named Entity Recognition](https://mlsanity.com/paper/2008.07347/) (2020)

## Built on by (most cited first, 3 of 3)

- [AIONER: All-in-one scheme-based biomedical named entity recognition using deep learning](https://mlsanity.com/paper/2211.16944/) (2022)
- [BELHD: Improving Biomedical Entity Linking with Homonoym Disambiguation](https://mlsanity.com/paper/2401.05125/) (2024)
- [BELXTR: Biomedical Entity Linking via Contextualized Token Retrieval](https://mlsanity.com/paper/2609.25859/) (2026)

## Abstract (arXiv)

The automatic assignment of species information to the corresponding genes in a research article is a critically important step in the gene normalization task, whereby a gene mention is normalized and linked to a database record or identifier by a text-mining algorithm. Existing methods typically rely on heuristic rules based on gene and species co-occurrence in the article, but their accuracy is suboptimal. We therefore developed a high-performance method, using a novel deep learning-based framework, to classify whether there is a relation between a gene and a species. Instead of the traditional binary classification framework in which all possible pairs of genes and species in the same article are evaluated, we treat the problem as a sequence-labeling task such that only a fraction of the pairs needs to be considered. Our benchmarking results show that our approach obtains significantly higher performance compared to that of the rule-based baseline method for the species assignment task (from 65.8% to 81.3% in accuracy). The source code and data for species assignment are freely available at https://github.com/ncbi/SpeciesAssignment.
