# Deep Normed Embeddings for Patient Representation

arXiv: https://arxiv.org/abs/2204.05477 · HTML: https://mlsanity.com/paper/2204.05477/

## Key facts

- Cited by 1 papers in the map (data through 14 Oct 2026).
- Builds on 23 of its 37 references that are in the map.
- First posted on arXiv 12 Apr 2022.

## Builds on (most cited first, 23 of 23)

- [Adam: A Method for Stochastic Optimization](https://mlsanity.com/paper/1412.6980/) (2014)
- [A Simple Framework for Contrastive Learning of Visual Representations](https://mlsanity.com/paper/2002.05709/) (2020)
- [Representation Learning with Contrastive Predictive Coding](https://mlsanity.com/paper/1807.03748/) (2018)
- [Momentum Contrast for Unsupervised Visual Representation Learning](https://mlsanity.com/paper/1911.05722/) (2019)
- [FaceNet: A Unified Embedding for Face Recognition and Clustering](https://mlsanity.com/paper/1503.03832/) (2015)
- [Supervised Contrastive Learning](https://mlsanity.com/paper/2004.11362/) (2020)
- [Improved Baselines with Momentum Contrastive Learning](https://mlsanity.com/paper/2003.04297/) (2020)
- [Geometric Deep Learning: Grids, Groups, Graphs, Geodesics, and Gauges](https://mlsanity.com/paper/2104.13478/) (2021)
- [A Distributional Perspective on Reinforcement Learning](https://mlsanity.com/paper/1707.06887/) (2017)
- [SphereFace: Deep Hypersphere Embedding for Face Recognition](https://mlsanity.com/paper/1704.08063/) (2017)
- [Deep metric learning using Triplet network](https://mlsanity.com/paper/1412.6622/) (2014)
- [Understanding Dimensional Collapse in Contrastive Self-supervised Learning](https://mlsanity.com/paper/2110.09348/) (2021)
- [Provable Benefit of Orthogonal Initialization in Optimizing Deep Linear Networks](https://mlsanity.com/paper/2001.05992/) (2020)
- [Deep Reinforcement Learning for Sepsis Treatment](https://mlsanity.com/paper/1711.09602/) (2017)
- [Evaluating Reinforcement Learning Algorithms in Observational Health Settings](https://mlsanity.com/paper/1805.12298/) (2018)
- [Deep Representation Learning of Electronic Health Records to Unlock Patient Stratification at Scale](https://mlsanity.com/paper/2003.06516/) (2020)
- [An Empirical Study of Representation Learning for Reinforcement Learning in Healthcare](https://mlsanity.com/paper/2011.11235/) (2020)
- [Neighborhood Contrastive Learning Applied to Online Patient Monitoring](https://mlsanity.com/paper/2106.05142/) (2021)
- [Improving Clinical Predictions through Unsupervised Time Series Representation Learning](https://mlsanity.com/paper/1812.00490/) (2018)
- [Unifying Cardiovascular Modelling with Deep Reinforcement Learning for Uncertainty Aware Control of Sepsis Treatment](https://mlsanity.com/paper/2101.08477/) (2021)
- [Optimizing Sequential Medical Treatments with Auto-Encoding Heuristic Search in POMDPs](https://mlsanity.com/paper/1905.07465/) (2019)
- [Contrastive Semi-supervised Learning for ASR](https://mlsanity.com/paper/2103.05149/) (2021)
- [Defining Admissible Rewards for High Confidence Policy Evaluation](https://mlsanity.com/paper/1905.13167/) (2019)

## Built on by (most cited first, 1 of 1)

- [Reinforcement Learning For Survival, A Clinically Motivated Method For Critically Ill Patients](https://mlsanity.com/paper/2207.08040/) (2022)

## Abstract (arXiv)

We introduce a novel contrastive representation learning objective and a training scheme for clinical time series. Specifically, we project high dimensional EHR. data to a closed unit ball of low dimension, encoding geometric priors so that the origin represents an idealized perfect health state and the Euclidean norm is associated with the patient's mortality risk. Moreover, using septic patients as an example, we show how we could learn to associate the angle between two vectors with the different organ system failures, thereby, learning a compact representation which is indicative of both mortality risk and specific organ failure. We show how the learned embedding can be used for online patient monitoring, can supplement clinicians and improve performance of downstream machine learning tasks. This work was partially motivated from the desire and the need to introduce a systematic way of defining intermediate rewards for Reinforcement Learning in critical care medicine. Hence, we also show how such a design in terms of the learned embedding can result in qualitatively different policies and value distributions, as compared with using only terminal rewards.
