# Explainable and Interpretable Diabetic Retinopathy Classification Based on Neural-Symbolic Learning

arXiv: https://arxiv.org/abs/2204.00624 · HTML: https://mlsanity.com/paper/2204.00624/

## Key facts

- Cited by 2 papers in the map (data through 14 Oct 2026).
- Builds on 17 of its 34 references that are in the map.
- First posted on arXiv 1 Apr 2022.

## Builds on (most cited first, 17 of 17)

- [Deep Residual Learning for Image Recognition](https://mlsanity.com/paper/1512.03385/) (2015)
- [U-Net: Convolutional Networks for Biomedical Image Segmentation](https://mlsanity.com/paper/1505.04597/) (2015)
- [Grad-CAM: Visual Explanations from Deep Networks via Gradient-based Localization](https://mlsanity.com/paper/1610.02391/) (2016)
- [A Unified Approach to Interpreting Model Predictions](https://mlsanity.com/paper/1705.07874/) (2017)
- [Axiomatic Attribution for Deep Networks](https://mlsanity.com/paper/1703.01365/) (2017)
- [Learning Deep Features for Discriminative Localization](https://mlsanity.com/paper/1512.04150/) (2015)
- [SmoothGrad: removing noise by adding noise](https://mlsanity.com/paper/1706.03825/) (2017)
- [Dynamic Routing Between Capsules](https://mlsanity.com/paper/1710.09829/) (2017)
- [Neural Probabilistic Logic Programming in DeepProbLog](https://mlsanity.com/paper/1907.08194/) (2019)
- [Neural-Symbolic VQA: Disentangling Reasoning from Vision and Language Understanding](https://mlsanity.com/paper/1810.02338/) (2018)
- [Neurosymbolic AI: The 3rd Wave](https://mlsanity.com/paper/2012.05876/) (2020)
- [Neural-Symbolic Learning and Reasoning: A Survey and Interpretation](https://mlsanity.com/paper/1711.03902/) (2017)
- [Neural-Symbolic Computing: An Effective Methodology for Principled Integration of Machine Learning and Reasoning](https://mlsanity.com/paper/1905.06088/) (2019)
- [Logical Neural Networks](https://mlsanity.com/paper/2006.13155/) (2020)
- [Zoom-in-Net: Deep Mining Lesions for Diabetic Retinopathy Detection](https://mlsanity.com/paper/1706.04372/) (2017)
- [Lesion detection and Grading of Diabetic Retinopathy via Two-stages Deep Convolutional Neural Networks](https://mlsanity.com/paper/1705.00771/) (2017)
- [Diabetic Retinopathy Detection via Deep Convolutional Networks for Discriminative Localization and Visual Explanation](https://mlsanity.com/paper/1703.10757/) (2017)

## Built on by (most cited first, 2 of 2)

- [A ChatGPT Aided Explainable Framework for Zero-Shot Medical Image Diagnosis](https://mlsanity.com/paper/2307.01981/) (2023)
- [Neuro-Symbolic Learning: Principles and Applications in Ophthalmology](https://mlsanity.com/paper/2208.00374/) (2022)

## Abstract (arXiv)

In this paper, we propose an explainable and interpretable diabetic retinopathy (ExplainDR) classification model based on neural-symbolic learning. To gain explainability, a highlevel symbolic representation should be considered in decision making. Specifically, we introduce a human-readable symbolic representation, which follows a taxonomy style of diabetic retinopathy characteristics related to eye health conditions to achieve explainability. We then include humanreadable features obtained from the symbolic representation in the disease prediction. Experimental results on a diabetic retinopathy classification dataset show that our proposed ExplainDR method exhibits promising performance when compared to that from state-of-the-art methods applied to the IDRiD dataset, while also providing interpretability and explainability.