# Translation Consistent Semi-supervised Segmentation for 3D Medical Images

arXiv: https://arxiv.org/abs/2203.14523 · HTML: https://mlsanity.com/paper/2203.14523/

## Key facts

- Cited by 13 papers in the map (data through 14 Oct 2026).
- Builds on 44 of its 87 references that are in the map.
- First posted on arXiv 28 Mar 2022.

## Builds on (most cited first, 30 of 44)

- [U-Net: Convolutional Networks for Biomedical Image Segmentation](https://mlsanity.com/paper/1505.04597/) (2015)
- [CutMix: Regularization Strategy to Train Strong Classifiers with Localizable Features](https://mlsanity.com/paper/1905.04899/) (2019)
- [Unsupervised Learning of Visual Features by Contrasting Cluster Assignments](https://mlsanity.com/paper/2006.09882/) (2020)
- [V-Net: Fully Convolutional Neural Networks for Volumetric Medical Image Segmentation](https://mlsanity.com/paper/1606.04797/) (2016)
- [TransUNet: Transformers Make Strong Encoders for Medical Image Segmentation](https://mlsanity.com/paper/2102.04306/) (2021)
- [UNet++: A Nested U-Net Architecture for Medical Image Segmentation](https://mlsanity.com/paper/1807.10165/) (2018)
- [3D U-Net: Learning Dense Volumetric Segmentation from Sparse Annotation](https://mlsanity.com/paper/1606.06650/) (2016)
- [MixMatch: A Holistic Approach to Semi-Supervised Learning](https://mlsanity.com/paper/1905.02249/) (2019)
- [Temporal Ensembling for Semi-Supervised Learning](https://mlsanity.com/paper/1610.02242/) (2016)
- [Deep Clustering for Unsupervised Learning of Visual Features](https://mlsanity.com/paper/1807.05520/) (2018)
- [ADVENT: Adversarial Entropy Minimization for Domain Adaptation in Semantic Segmentation](https://mlsanity.com/paper/1811.12833/) (2018)
- [Dense Contrastive Learning for Self-Supervised Visual Pre-Training](https://mlsanity.com/paper/2011.09157/) (2020)
- [Semi-Supervised Semantic Segmentation with Cross Pseudo Supervision](https://mlsanity.com/paper/2106.01226/) (2021)
- [Uncertainty-aware Self-ensembling Model for Semi-supervised 3D Left Atrium Segmentation](https://mlsanity.com/paper/1907.07034/) (2019)
- [Semi-Supervised Semantic Segmentation with Cross-Consistency Training](https://mlsanity.com/paper/2003.09005/) (2020)
- [In Defense of Pseudo-Labeling: An Uncertainty-Aware Pseudo-label Selection Framework for Semi-Supervised Learning](https://mlsanity.com/paper/2101.06329/) (2021)
- [Interpolation Consistency Training for Semi-Supervised Learning](https://mlsanity.com/paper/1903.03825/) (2019)
- [Exploring Cross-Image Pixel Contrast for Semantic Segmentation](https://mlsanity.com/paper/2101.11939/) (2021)
- [Semi-Supervised Semantic Segmentation Using Unreliable Pseudo-Labels](https://mlsanity.com/paper/2203.03884/) (2022)
- [Confidence Calibration and Predictive Uncertainty Estimation for Deep Medical Image Segmentation](https://mlsanity.com/paper/1911.13273/) (2019)
- [Shape-aware Semi-supervised 3D Semantic Segmentation for Medical Images](https://mlsanity.com/paper/2007.10732/) (2020)
- [NLNL: Negative Learning for Noisy Labels](https://mlsanity.com/paper/1908.07387/) (2019)
- [Deep Co-Training for Semi-Supervised Image Recognition](https://mlsanity.com/paper/1803.05984/) (2018)
- [Guided Collaborative Training for Pixel-wise Semi-Supervised Learning](https://mlsanity.com/paper/2008.05258/) (2020)
- [Perturbed and Strict Mean Teachers for Semi-supervised Semantic Segmentation](https://mlsanity.com/paper/2111.12903/) (2021)
- [Semi-supervised Semantic Segmentation with Directional Context-aware Consistency](https://mlsanity.com/paper/2106.14133/) (2021)
- [Mutual Consistency Learning for Semi-supervised Medical Image Segmentation](https://mlsanity.com/paper/2109.09960/) (2021)
- [Semi-supervised Left Atrium Segmentation with Mutual Consistency Training](https://mlsanity.com/paper/2103.02911/) (2021)
- [Efficient Semi-Supervised Gross Target Volume of Nasopharyngeal Carcinoma Segmentation via Uncertainty Rectified Pyramid Consistency](https://mlsanity.com/paper/2012.07042/) (2020)
- [Semi-Supervised Medical Image Segmentation via Cross Teaching between CNN and Transformer](https://mlsanity.com/paper/2112.04894/) (2021)

## Built on by (most cited first, 13 of 13)

- [Medical SAM3: A Foundation Model for Universal Prompt-Driven Medical Image Segmentation](https://mlsanity.com/paper/2601.10880/) (2026)
- [FairDomain: Achieving Fairness in Cross-Domain Medical Image Segmentation and Classification](https://mlsanity.com/paper/2407.08813/) (2024)
- [Compete to Win: Enhancing Pseudo Labels for Barely-supervised Medical Image Segmentation](https://mlsanity.com/paper/2304.07519/) (2023)
- [FairSeg: A Large-Scale Medical Image Segmentation Dataset for Fairness Learning Using Segment Anything Model with Fair Error-Bound Scaling](https://mlsanity.com/paper/2311.02189/) (2023)
- [From Gaze to Insight: Bridging Human Visual Attention and Vision Language Model Explanation for Weakly-Supervised Medical Image Segmentation](https://mlsanity.com/paper/2504.11368/) (2025)
- [Cross- and Intra-image Prototypical Learning for Multi-label Disease Diagnosis and Interpretation](https://mlsanity.com/paper/2411.04607/) (2024)
- [Dual Cross-image Semantic Consistency with Self-aware Pseudo Labeling for Semi-supervised Medical Image Segmentation](https://mlsanity.com/paper/2507.21440/) (2025)
- [Leveraging Labelled Data Knowledge: A Cooperative Rectification Learning Network for Semi-supervised 3D Medical Image Segmentation](https://mlsanity.com/paper/2502.11456/) (2025)
- [BARL: Bilateral Alignment in Representation and Label Spaces for Semi-Supervised Volumetric Medical Image Segmentation](https://mlsanity.com/paper/2510.16863/) (2025)
- [AstMatch: Adversarial Self-training Consistency Framework for Semi-Supervised Medical Image Segmentation](https://mlsanity.com/paper/2406.19649/) (2024)
- [C3S3: Complementary Competition and Contrastive Selection for Semi-Supervised Medical Image Segmentation](https://mlsanity.com/paper/2506.07368/) (2025)
- [Not All Pixels Are Equal: Pixel-wise Meta-Learning for Medical Segmentation with Noisy Labels](https://mlsanity.com/paper/2511.18894/) (2025)
- [Are We Overconfident in Models and Results for Semi-Supervised 3D Medical Image Segmentation?](https://mlsanity.com/paper/2605.25561/) (2026)

## Abstract (arXiv)

3D medical image segmentation methods have been successful, but their dependence on large amounts of voxel-level annotated data is a disadvantage that needs to be addressed given the high cost to obtain such annotation. Semi-supervised learning (SSL) solve this issue by training models with a large unlabelled and a small labelled dataset. The most successful SSL approaches are based on consistency learning that minimises the distance between model responses obtained from perturbed views of the unlabelled data. These perturbations usually keep the spatial input context between views fairly consistent, which may cause the model to learn segmentation patterns from the spatial input contexts instead of the segmented objects. In this paper, we introduce the Translation Consistent Co-training (TraCoCo) which is a consistency learning SSL method that perturbs the input data views by varying their spatial input context, allowing the model to learn segmentation patterns from visual objects. Furthermore, we propose the replacement of the commonly used mean squared error (MSE) semi-supervised loss by a new Cross-model confident Binary Cross entropy (CBC) loss, which improves training convergence and keeps the robustness to co-training pseudo-labelling mistakes. We also extend CutMix augmentation to 3D SSL to further improve generalisation. Our TraCoCo shows state-of-the-art results for the Left Atrium (LA) and Brain Tumor Segmentation (BRaTS19) datasets with different backbones. Our code is available at https://github.com/yyliu01/TraCoCo.
