# LILE: Look In-Depth before Looking Elsewhere -- A Dual Attention Network using Transformers for Cross-Modal Information Retrieval in Histopathology Archives

arXiv: https://arxiv.org/abs/2203.01445 · HTML: https://mlsanity.com/paper/2203.01445/

## Key facts

- Cited by 5 papers in the map (data through 14 Oct 2026).
- Builds on 36 of its 53 references that are in the map.
- First posted on arXiv 2 Mar 2022.

## Builds on (most cited first, 30 of 36)

- [Attention Is All You Need](https://mlsanity.com/paper/1706.03762/) (2017)
- [Adam: A Method for Stochastic Optimization](https://mlsanity.com/paper/1412.6980/) (2014)
- [Learning Transferable Visual Models From Natural Language Supervision](https://mlsanity.com/paper/2103.00020/) (2021)
- [An Image is Worth 16x16 Words: Transformers for Image Recognition at Scale](https://mlsanity.com/paper/2010.11929/) (2020)
- [Microsoft COCO: Common Objects in Context](https://mlsanity.com/paper/1405.0312/) (2014)
- [RoBERTa: A Robustly Optimized BERT Pretraining Approach](https://mlsanity.com/paper/1907.11692/) (2019)
- [Faster R-CNN: Towards Real-Time Object Detection with Region Proposal Networks](https://mlsanity.com/paper/1506.01497/) (2015)
- [A Style-Based Generator Architecture for Generative Adversarial Networks](https://mlsanity.com/paper/1812.04948/) (2018)
- [Training data-efficient image transformers & distillation through attention](https://mlsanity.com/paper/2012.12877/) (2020)
- [Scaling Up Visual and Vision-Language Representation Learning With Noisy Text Supervision](https://mlsanity.com/paper/2102.05918/) (2021)
- [ViLBERT: Pretraining Task-Agnostic Visiolinguistic Representations for Vision-and-Language Tasks](https://mlsanity.com/paper/1908.02265/) (2019)
- [Don't Stop Pretraining: Adapt Language Models to Domains and Tasks](https://mlsanity.com/paper/2004.10964/) (2020)
- [LXMERT: Learning Cross-Modality Encoder Representations from Transformers](https://mlsanity.com/paper/1908.07490/) (2019)
- [Oscar: Object-Semantics Aligned Pre-training for Vision-Language Tasks](https://mlsanity.com/paper/2004.06165/) (2020)
- [Effective Approaches to Attention-based Neural Machine Translation](https://mlsanity.com/paper/1508.04025/) (2015)
- [Deep Visual-Semantic Alignments for Generating Image Descriptions](https://mlsanity.com/paper/1412.2306/) (2014)
- [Stacked Cross Attention for Image-Text Matching](https://mlsanity.com/paper/1803.08024/) (2018)
- [Attention-Based Models for Speech Recognition](https://mlsanity.com/paper/1506.07503/) (2015)
- [Memory Networks](https://mlsanity.com/paper/1410.3916/) (2014)
- [12-in-1: Multi-Task Vision and Language Representation Learning](https://mlsanity.com/paper/1912.02315/) (2019)
- [Unifying Visual-Semantic Embeddings with Multimodal Neural Language Models](https://mlsanity.com/paper/1411.2539/) (2014)
- [Visual Semantic Reasoning for Image-Text Matching](https://mlsanity.com/paper/1909.02701/) (2019)
- [Support-set bottlenecks for video-text representation learning](https://mlsanity.com/paper/2010.02824/) (2020)
- [IMRAM: Iterative Matching with Recurrent Attention Memory for Cross-Modal Image-Text Retrieval](https://mlsanity.com/paper/2003.03772/) (2020)
- [Deep Fragment Embeddings for Bidirectional Image Sentence Mapping](https://mlsanity.com/paper/1406.5679/) (2014)
- [Polysemous Visual-Semantic Embedding for Cross-Modal Retrieval](https://mlsanity.com/paper/1906.04402/) (2019)
- [Learning Semantic Concepts and Order for Image and Sentence Matching](https://mlsanity.com/paper/1712.02036/) (2017)
- [Multiple Instance Captioning: Learning Representations from Histopathology Textbooks and Articles](https://mlsanity.com/paper/2103.05121/) (2021)
- [MDNet: A Semantically and Visually Interpretable Medical Image Diagnosis Network](https://mlsanity.com/paper/1707.02485/) (2017)
- [Look, Imagine and Match: Improving Textual-Visual Cross-Modal Retrieval with Generative Models](https://mlsanity.com/paper/1711.06420/) (2017)

## Built on by (most cited first, 5 of 5)

- [Towards a Visual-Language Foundation Model for Computational Pathology](https://mlsanity.com/paper/2307.12914/) (2023)
- [A scoping review on multimodal deep learning in biomedical images and texts](https://mlsanity.com/paper/2307.07362/) (2023)
- [On Image Search in Histopathology](https://mlsanity.com/paper/2401.08699/) (2024)
- [A Survey on Image-text Multimodal Models](https://mlsanity.com/paper/2309.15857/) (2023)
- [UniSemAlign: Text-Prototype Alignment with a Foundation Encoder for Semi-Supervised Histopathology Segmentation](https://mlsanity.com/paper/2604.09169/) (2026)

## Abstract (arXiv)

The volume of available data has grown dramatically in recent years in many applications. Furthermore, the age of networks that used multiple modalities separately has practically ended. Therefore, enabling bidirectional cross-modality data retrieval capable of processing has become a requirement for many domains and disciplines of research. This is especially true in the medical field, as data comes in a multitude of types, including various types of images and reports as well as molecular data. Most contemporary works apply cross attention to highlight the essential elements of an image or text in relation to the other modalities and try to match them together. However, regardless of their importance in their own modality, these approaches usually consider features of each modality equally. In this study, self-attention as an additional loss term will be proposed to enrich the internal representation provided into the cross attention module. This work suggests a novel architecture with a new loss term to help represent images and texts in the joint latent space. Experiment results on two benchmark datasets, i.e. MS-COCO and ARCH, show the effectiveness of the proposed method.
