# Separable-HoverNet and Instance-YOLO for Colon Nuclei Identification and Counting

arXiv: https://arxiv.org/abs/2203.00262 · HTML: https://mlsanity.com/paper/2203.00262/

## Key facts

- No citing papers in the map yet (data through 14 Oct 2026).
- Builds on 8 of its 8 references that are in the map.
- First posted on arXiv 1 Mar 2022.

## Builds on (most cited first, 8 of 8)

- [U-Net: Convolutional Networks for Biomedical Image Segmentation](https://mlsanity.com/paper/1505.04597/) (2015)
- [Mask R-CNN](https://mlsanity.com/paper/1703.06870/) (2017)
- [Deep High-Resolution Representation Learning for Human Pose Estimation](https://mlsanity.com/paper/1902.09212/) (2019)
- [HoVer-Net: Simultaneous Segmentation and Classification of Nuclei in Multi-Tissue Histology Images](https://mlsanity.com/paper/1812.06499/) (2018)
- [SOLO: Segmenting Objects by Locations](https://mlsanity.com/paper/1912.04488/) (2019)
- [Lizard: A Large-Scale Dataset for Colonic Nuclear Instance Segmentation and Classification](https://mlsanity.com/paper/2108.11195/) (2021)
- [Equalized Focal Loss for Dense Long-Tailed Object Detection](https://mlsanity.com/paper/2201.02593/) (2022)
- [CoNIC: Colon Nuclei Identification and Counting Challenge 2022](https://mlsanity.com/paper/2111.14485/) (2021)

## Abstract (arXiv)

Nuclear segmentation, classification and quantification within Haematoxylin & Eosin stained histology images enables the extraction of interpretable cell-based features that can be used in downstream explainable models in computational pathology (CPath). However, automatic recognition of different nuclei is faced with a major challenge in that there are several different types of nuclei, some of them exhibiting large intraclass variability. In this work, we propose an approach that combine Separable-HoverNet and Instance-YOLOv5 to indentify colon nuclei small and unbalanced. Our approach can achieve mPQ+ 0.389 on the Segmentation and Classification-Preliminary Test Dataset and r2 0.599 on the Cellular Composition-Preliminary Test Dataset on ISBI 2022 CoNIC Challenge.