# EdgeMixup: Improving Fairness for Skin Disease Classification and Segmentation

arXiv: https://arxiv.org/abs/2202.13883 · HTML: https://mlsanity.com/paper/2202.13883/

## Key facts

- Cited by 3 papers in the map (data through 14 Oct 2026).
- Builds on 13 of its 33 references that are in the map.
- First posted on arXiv 28 Feb 2022.

## Builds on (most cited first, 13 of 13)

- [Deep Residual Learning for Image Recognition](https://mlsanity.com/paper/1512.03385/) (2015)
- [U-Net: Convolutional Networks for Biomedical Image Segmentation](https://mlsanity.com/paper/1505.04597/) (2015)
- [Towards Deep Learning Models Resistant to Adversarial Attacks](https://mlsanity.com/paper/1706.06083/) (2017)
- [Equality of Opportunity in Supervised Learning](https://mlsanity.com/paper/1610.02413/) (2016)
- [Man is to Computer Programmer as Woman is to Homemaker? Debiasing Word Embeddings](https://mlsanity.com/paper/1607.06520/) (2016)
- [Skin Lesion Analysis Toward Melanoma Detection 2018: A Challenge Hosted by the International Skin Imaging Collaboration (ISIC)](https://mlsanity.com/paper/1902.03368/) (2019)
- [Mitigating Unwanted Biases with Adversarial Learning](https://mlsanity.com/paper/1801.07593/) (2018)
- [Adversarial Training for Free!](https://mlsanity.com/paper/1904.12843/) (2019)
- [Fairness in Machine Learning: A Survey](https://mlsanity.com/paper/2010.04053/) (2020)
- [Data Decisions and Theoretical Implications when Adversarially Learning Fair Representations](https://mlsanity.com/paper/1707.00075/) (2017)
- [Dense Extreme Inception Network: Towards a Robust CNN Model for Edge Detection](https://mlsanity.com/paper/1909.01955/) (2019)
- [Towards Accuracy-Fairness Paradox: Adversarial Example-based Data Augmentation for Visual Debiasing](https://mlsanity.com/paper/2007.13632/) (2020)
- [TARA: Training and Representation Alteration for AI Fairness and Domain Generalization](https://mlsanity.com/paper/2012.06387/) (2020)

## Built on by (most cited first, 3 of 3)

- [Enhancing Fairness in Skin Lesion Classification for Medical Diagnosis Using Prune Learning](https://mlsanity.com/paper/2509.00745/) (2025)
- [Mitigating Urban-Rural Disparities in Contrastive Representation Learning with Satellite Imagery](https://mlsanity.com/paper/2211.08672/) (2022)
- [Evaluating Fairness and Mitigating Bias in Machine Learning: A Novel Technique using Tensor Data and Bayesian Regression](https://mlsanity.com/paper/2506.11627/) (2025)

## Abstract (arXiv)

Skin lesions can be an early indicator of a wide range of infectious and other diseases. The use of deep learning (DL) models to diagnose skin lesions has great potential in assisting clinicians with prescreening patients. However, these models often learn biases inherent in training data, which can lead to a performance gap in the diagnosis of people with light and/or dark skin tones. To the best of our knowledge, limited work has been done on identifying, let alone reducing, model bias in skin disease classification and segmentation. In this paper, we examine DL fairness and demonstrate the existence of bias in classification and segmentation models for subpopulations with darker skin tones compared to individuals with lighter skin tones, for specific diseases including Lyme, Tinea Corporis and Herpes Zoster. Then, we propose a novel preprocessing, data alteration method, called EdgeMixup, to improve model fairness with a linear combination of an input skin lesion image and a corresponding a predicted edge detection mask combined with color saturation alteration. For the task of skin disease classification, EdgeMixup outperforms much more complex competing methods such as adversarial approaches, achieving a 10.99% reduction in accuracy gap between light and dark skin tone samples, and resulting in 8.4% improved performance for an underrepresented subpopulation.