# Cell nuclei classification in histopathological images using hybrid OLConvNet

arXiv: https://arxiv.org/abs/2202.10177 · HTML: https://mlsanity.com/paper/2202.10177/

## Key facts

- Cited by 1 papers in the map (data through 14 Oct 2026).
- Builds on 9 of its 49 references that are in the map.
- First posted on arXiv 21 Feb 2022.

## Builds on (most cited first, 9 of 9)

- [Deep Residual Learning for Image Recognition](https://mlsanity.com/paper/1512.03385/) (2015)
- [Very Deep Convolutional Networks for Large-Scale Image Recognition](https://mlsanity.com/paper/1409.1556/) (2014)
- [Densely Connected Convolutional Networks](https://mlsanity.com/paper/1608.06993/) (2016)
- [Rethinking the Inception Architecture for Computer Vision](https://mlsanity.com/paper/1512.00567/) (2015)
- [Going Deeper with Convolutions](https://mlsanity.com/paper/1409.4842/) (2014)
- [A systematic study of the class imbalance problem in convolutional neural networks](https://mlsanity.com/paper/1710.05381/) (2017)
- [DeCAF: A Deep Convolutional Activation Feature for Generic Visual Recognition](https://mlsanity.com/paper/1310.1531/) (2013)
- [Caffe: Convolutional Architecture for Fast Feature Embedding](https://mlsanity.com/paper/1408.5093/) (2014)
- [Return of the Devil in the Details: Delving Deep into Convolutional Nets](https://mlsanity.com/paper/1405.3531/) (2014)

## Built on by (most cited first, 1 of 1)

- [Bag of Visual Words (BoVW) with Deep Features -- Patch Classification Model for Limited Dataset of Breast Tumours](https://mlsanity.com/paper/2202.10701/) (2022)

## Abstract (arXiv)

Computer-aided histopathological image analysis for cancer detection is a major research challenge in the medical domain. Automatic detection and classification of nuclei for cancer diagnosis impose a lot of challenges in developing state of the art algorithms due to the heterogeneity of cell nuclei and data set variability. Recently, a multitude of classification algorithms has used complex deep learning models for their dataset. However, most of these methods are rigid and their architectural arrangement suffers from inflexibility and non-interpretability. In this research article, we have proposed a hybrid and flexible deep learning architecture OLConvNet that integrates the interpretability of traditional object-level features and generalization of deep learning features by using a shallower Convolutional Neural Network (CNN) named as CNN3L. CNN3L reduces the training time by training fewer parameters and hence eliminating space constraints imposed by deeper algorithms. We used F1-score and multiclass Area Under the Curve (AUC) performance parameters to compare the results. To further strengthen the viability of our architectural approach, we tested our proposed methodology with state of the art deep learning architectures AlexNet, VGG16, VGG19, ResNet50, InceptionV3, and DenseNet121 as backbone networks. After a comprehensive analysis of classification results from all four architectures, we observed that our proposed model works well and perform better than contemporary complex algorithms.