# Enhancing Organ at Risk Segmentation with Improved Deep Neural Networks

arXiv: https://arxiv.org/abs/2202.01866 · HTML: https://mlsanity.com/paper/2202.01866/

## Key facts

- Cited by 2 papers in the map (data through 14 Oct 2026).
- Builds on 8 of its 14 references that are in the map.
- First posted on arXiv 3 Feb 2022.

## Builds on (most cited first, 8 of 8)

- [U-Net: Convolutional Networks for Biomedical Image Segmentation](https://mlsanity.com/paper/1505.04597/) (2015)
- [EfficientNet: Rethinking Model Scaling for Convolutional Neural Networks](https://mlsanity.com/paper/1905.11946/) (2019)
- [Fully Convolutional Networks for Semantic Segmentation](https://mlsanity.com/paper/1411.4038/) (2014)
- [UNet++: A Nested U-Net Architecture for Medical Image Segmentation](https://mlsanity.com/paper/1807.10165/) (2018)
- [3D U-Net: Learning Dense Volumetric Segmentation from Sparse Annotation](https://mlsanity.com/paper/1606.06650/) (2016)
- [Cyclical Learning Rates for Training Neural Networks](https://mlsanity.com/paper/1506.01186/) (2015)
- [nnU-Net: Self-adapting Framework for U-Net-Based Medical Image Segmentation](https://mlsanity.com/paper/1809.10486/) (2018)
- [OpenKBP: The open-access knowledge-based planning grand challenge](https://mlsanity.com/paper/2011.14076/) (2020)

## Built on by (most cited first, 2 of 2)

- [An Efficient Multi-Scale Fusion Network for 3D Organ at Risk (OAR) Segmentation](https://mlsanity.com/paper/2208.07417/) (2022)
- [Towards more precise automatic analysis: a comprehensive survey of deep learning-based multi-organ segmentation](https://mlsanity.com/paper/2303.00232/) (2023)

## Abstract (arXiv)

Organ at risk (OAR) segmentation is a crucial step for treatment planning and outcome determination in radiotherapy treatments of cancer patients. Several deep learning based segmentation algorithms have been developed in recent years, however, U-Net remains the de facto algorithm designed specifically for biomedical image segmentation and has spawned many variants with known weaknesses. In this study, our goal is to present simple architectural changes in U-Net to improve its accuracy and generalization properties. Unlike many other available studies evaluating their algorithms on single center data, we thoroughly evaluate several variations of U-Net as well as our proposed enhanced architecture on multiple data sets for an extensive and reliable study of the OAR segmentation problem. Our enhanced segmentation model includes (a)architectural changes in the loss function, (b)optimization framework, and (c)convolution type. Testing on three publicly available multi-object segmentation data sets, we achieved an average of 80% dice score compared to the baseline U-Net performance of 63%.