# POTHER: Patch-Voted Deep Learning-Based Chest X-ray Bias Analysis for COVID-19 Detection

arXiv: https://arxiv.org/abs/2201.09360 · HTML: https://mlsanity.com/paper/2201.09360/

## Key facts

- No citing papers in the map yet (data through 14 Oct 2026).
- Builds on 13 of its 26 references that are in the map.
- First posted on arXiv 23 Jan 2022.

## Builds on (most cited first, 13 of 13)

- [Deep Residual Learning for Image Recognition](https://mlsanity.com/paper/1512.03385/) (2015)
- [U-Net: Convolutional Networks for Biomedical Image Segmentation](https://mlsanity.com/paper/1505.04597/) (2015)
- [Grad-CAM++: Improved Visual Explanations for Deep Convolutional Networks](https://mlsanity.com/paper/1710.11063/) (2017)
- [A Survey on Explainable Artificial Intelligence (XAI): Towards Medical XAI](https://mlsanity.com/paper/1907.07374/) (2019)
- [COVID-Net: A Tailored Deep Convolutional Neural Network Design for Detection of COVID-19 Cases from Chest X-Ray Images](https://mlsanity.com/paper/2003.09871/) (2020)
- [COVID-19 Image Data Collection: Prospective Predictions Are the Future](https://mlsanity.com/paper/2006.11988/) (2020)
- [Deep Learning for Chest X-ray Analysis: A Survey](https://mlsanity.com/paper/2103.08700/) (2021)
- [Deep Learning COVID-19 Features on CXR using Limited Training Data Sets](https://mlsanity.com/paper/2004.05758/) (2020)
- [Deep-COVID: Predicting COVID-19 From Chest X-Ray Images Using Deep Transfer Learning](https://mlsanity.com/paper/2004.09363/) (2020)
- [Do Explanations Reflect Decisions? A Machine-centric Strategy to Quantify the Performance of Explainability Algorithms](https://mlsanity.com/paper/1910.07387/) (2019)
- [A Critic Evaluation of Methods for COVID-19 Automatic Detection from X-Ray Images](https://mlsanity.com/paper/2004.12823/) (2020)
- [Iteratively Pruned Deep Learning Ensembles for COVID-19 Detection in Chest X-rays](https://mlsanity.com/paper/2004.08379/) (2020)
- [FetalNet: Multi-task Deep Learning Framework for Fetal Ultrasound Biometric Measurements](https://mlsanity.com/paper/2107.06943/) (2021)

## Abstract (arXiv)

A critical step in the fight against COVID-19, which continues to have a catastrophic impact on peoples lives, is the effective screening of patients presented in the clinics with severe COVID-19 symptoms. Chest radiography is one of the promising screening approaches. Many studies reported detecting COVID-19 in chest X-rays accurately using deep learning. A serious limitation of many published approaches is insufficient attention paid to explaining decisions made by deep learning models. Using explainable artificial intelligence methods, we demonstrate that model decisions may rely on confounding factors rather than medical pathology. After an analysis of potential confounding factors found on chest X-ray images, we propose a novel method to minimise their negative impact. We show that our proposed method is more robust than previous attempts to counter confounding factors such as ECG leads in chest X-rays that often influence model classification decisions. In addition to being robust, our method achieves results comparable to the state-of-the-art. The source code and pre-trained weights are publicly available at (https://github.com/tomek1911/POTHER).