# Individualized treatment rules under stochastic treatment cost constraints

arXiv: https://arxiv.org/abs/2201.06669 · HTML: https://mlsanity.com/paper/2201.06669/

## Key facts

- Cited by 3 papers in the map (data through 14 Oct 2026).
- First posted on arXiv 18 Jan 2022.

## Built on by (most cited first, 3 of 3)

- [MOSIC: Model-Agnostic Optimal Subgroup Identification with Multi-Constraint for Improved Reliability](https://mlsanity.com/paper/2504.20908/) (2025)
- [Incentive-Aware Synthetic Control: Accurate Counterfactual Estimation via Incentivized Exploration](https://mlsanity.com/paper/2312.16307/) (2023)
- [Towards Optimal Environmental Policies: Policy Learning under Arbitrary Bipartite Network Interference](https://mlsanity.com/paper/2410.08362/) (2024)

## Abstract (arXiv)

Estimation and evaluation of individualized treatment rules have been studied extensively, but real-world treatment resource constraints have received limited attention in existing methods. We investigate a setting in which treatment is intervened upon based on covariates to optimize the mean counterfactual outcome under treatment cost constraints when the treatment cost is random. In a particularly interesting special case, an instrumental variable corresponding to encouragement to treatment is intervened upon with constraints on the proportion receiving treatment. For such settings, we first develop a method to estimate optimal individualized treatment rules. We further construct an asymptotically efficient plug-in estimator of the corresponding average treatment effect relative to a given reference rule.
