# Self-Supervision and Multi-Task Learning: Challenges in Fine-Grained COVID-19 Multi-Class Classification from Chest X-rays

arXiv: https://arxiv.org/abs/2201.06052 · HTML: https://mlsanity.com/paper/2201.06052/

## Key facts

- Cited by 3 papers in the map (data through 14 Oct 2026).
- Builds on 14 of its 43 references that are in the map.
- First posted on arXiv 16 Jan 2022.

## Builds on (most cited first, 14 of 14)

- [Deep Residual Learning for Image Recognition](https://mlsanity.com/paper/1512.03385/) (2015)
- [Representation Learning with Contrastive Predictive Coding](https://mlsanity.com/paper/1807.03748/) (2018)
- [Densely Connected Convolutional Networks](https://mlsanity.com/paper/1608.06993/) (2016)
- [MobileNets: Efficient Convolutional Neural Networks for Mobile Vision Applications](https://mlsanity.com/paper/1704.04861/) (2017)
- [Improved Baselines with Momentum Contrastive Learning](https://mlsanity.com/paper/2003.04297/) (2020)
- [Context Encoders: Feature Learning by Inpainting](https://mlsanity.com/paper/1604.07379/) (2016)
- [CheXpert: A Large Chest Radiograph Dataset with Uncertainty Labels and Expert Comparison](https://mlsanity.com/paper/1901.07031/) (2019)
- [A Survey on Multi-Task Learning](https://mlsanity.com/paper/1707.08114/) (2017)
- [CheXNet: Radiologist-Level Pneumonia Detection on Chest X-Rays with Deep Learning](https://mlsanity.com/paper/1711.05225/) (2017)
- [Common pitfalls and recommendations for using machine learning to detect and prognosticate for COVID-19 using chest radiographs and CT scans](https://mlsanity.com/paper/2008.06388/) (2020)
- [BIMCV COVID-19+: a large annotated dataset of RX and CT images from COVID-19 patients](https://mlsanity.com/paper/2006.01174/) (2020)
- [MoCo-CXR: MoCo Pretraining Improves Representation and Transferability of Chest X-ray Models](https://mlsanity.com/paper/2010.05352/) (2020)
- [Self-supervised deep convolutional neural network for chest X-ray classification](https://mlsanity.com/paper/2103.03055/) (2021)
- [Coronavirus (COVID-19) Classification using CT Images by Machine Learning Methods](https://mlsanity.com/paper/2003.09424/) (2020)

## Built on by (most cited first, 3 of 3)

- [MGMT promoter methylation status prediction using MRI scans? An extensive experimental evaluation of deep learning models](https://mlsanity.com/paper/2304.00774/) (2023)
- [A Survey of the Impact of Self-Supervised Pretraining for Diagnostic Tasks with Radiological Images](https://mlsanity.com/paper/2309.02555/) (2023)
- [Efficient Vocabulary-Free Fine-Grained Visual Recognition in the Age of Multimodal LLMs](https://mlsanity.com/paper/2505.01064/) (2025)

## Abstract (arXiv)

Quick and accurate diagnosis is of paramount importance to mitigate the effects of COVID-19 infection, particularly for severe cases. Enormous effort has been put towards developing deep learning methods to classify and detect COVID-19 infections from chest radiography images. However, recently some questions have been raised surrounding the clinical viability and effectiveness of such methods. In this work, we investigate the impact of multi-task learning (classification and segmentation) on the ability of CNNs to differentiate between various appearances of COVID-19 infections in the lung. We also employ self-supervised pre-training approaches, namely MoCo and inpainting-CXR, to eliminate the dependence on expensive ground truth annotations for COVID-19 classification. Finally, we conduct a critical evaluation of the models to assess their deploy-readiness and provide insights into the difficulties of fine-grained COVID-19 multi-class classification from chest X-rays.