# Synthesising Electronic Health Records: Cystic Fibrosis Patient Group

arXiv: https://arxiv.org/abs/2201.05400 · HTML: https://mlsanity.com/paper/2201.05400/

## Key facts

- No citing papers in the map yet (data through 14 Oct 2026).
- Builds on 11 of its 24 references that are in the map.
- First posted on arXiv 14 Jan 2022.

## Builds on (most cited first, 11 of 11)

- [Improved Precision and Recall Metric for Assessing Generative Models](https://mlsanity.com/paper/1904.06991/) (2019)
- [Modeling Tabular data using Conditional GAN](https://mlsanity.com/paper/1907.00503/) (2019)
- [Reliable Fidelity and Diversity Metrics for Generative Models](https://mlsanity.com/paper/2002.09797/) (2020)
- [Assessing Generative Models via Precision and Recall](https://mlsanity.com/paper/1806.00035/) (2018)
- [Opacus: User-Friendly Differential Privacy Library in PyTorch](https://mlsanity.com/paper/2109.12298/) (2021)
- [Differentially Private Generative Adversarial Network](https://mlsanity.com/paper/1802.06739/) (2018)
- [Generating Multi-label Discrete Patient Records using Generative Adversarial Networks](https://mlsanity.com/paper/1703.06490/) (2017)
- [How Faithful is your Synthetic Data? Sample-level Metrics for Evaluating and Auditing Generative Models](https://mlsanity.com/paper/2102.08921/) (2021)
- [Synthesizing Tabular Data using Generative Adversarial Networks](https://mlsanity.com/paper/1811.11264/) (2018)
- [Conditional Wasserstein GAN-based Oversampling of Tabular Data for Imbalanced Learning](https://mlsanity.com/paper/2008.09202/) (2020)
- [AutoPrognosis: Automated Clinical Prognostic Modeling via Bayesian Optimization with Structured Kernel Learning](https://mlsanity.com/paper/1802.07207/) (2018)

## Abstract (arXiv)

Class imbalance can often degrade predictive performance of supervised learning algorithms. Balanced classes can be obtained by oversampling exact copies, with noise, or interpolation between nearest neighbours (as in traditional SMOTE methods). Oversampling tabular data using augmentation, as is typical in computer vision tasks, can be achieved with deep generative models. Deep generative models are effective data synthesisers due to their ability to capture complex underlying distributions. Synthetic data in healthcare can enhance interoperability between healthcare providers by ensuring patient privacy. Equipped with large synthetic datasets which do well to represent small patient groups, machine learning in healthcare can address the current challenges of bias and generalisability. This paper evaluates synthetic data generators ability to synthesise patient electronic health records. We test the utility of synthetic data for patient outcome classification, observing increased predictive performance when augmenting imbalanced datasets with synthetic data.