# Omni-Seg: A Single Dynamic Network for Multi-label Renal Pathology Image Segmentation using Partially Labeled Data

arXiv: https://arxiv.org/abs/2112.12665 · HTML: https://mlsanity.com/paper/2112.12665/

## Key facts

- Cited by 4 papers in the map (data through 14 Oct 2026).
- Builds on 12 of its 25 references that are in the map.
- First posted on arXiv 23 Dec 2021.

## Builds on (most cited first, 12 of 12)

- [U-Net: Convolutional Networks for Biomedical Image Segmentation](https://mlsanity.com/paper/1505.04597/) (2015)
- [Rethinking Atrous Convolution for Semantic Image Segmentation](https://mlsanity.com/paper/1706.05587/) (2017)
- [Group Normalization](https://mlsanity.com/paper/1803.08494/) (2018)
- [Med3D: Transfer Learning for 3D Medical Image Analysis](https://mlsanity.com/paper/1904.00625/) (2019)
- [DoDNet: Learning to segment multi-organ and tumors from multiple partially labeled datasets](https://mlsanity.com/paper/2011.10217/) (2020)
- [Multi-organ Segmentation over Partially Labeled Datasets with Multi-scale Feature Abstraction](https://mlsanity.com/paper/2001.00208/) (2020)
- [Fast Image Processing with Fully-Convolutional Networks](https://mlsanity.com/paper/1709.00643/) (2017)
- [Multi-Scale Coarse-to-Fine Segmentation for Screening Pancreatic Ductal Adenocarcinoma](https://mlsanity.com/paper/1807.02941/) (2018)
- [Computational Anatomy for Multi-Organ Analysis in Medical Imaging: A Review](https://mlsanity.com/paper/1812.08577/) (2018)
- [Crossbar-Net: A Novel Convolutional Network for Kidney Tumor Segmentation in CT Images](https://mlsanity.com/paper/1804.10484/) (2018)
- [Evaluating Transformer-based Semantic Segmentation Networks for Pathological Image Segmentation](https://mlsanity.com/paper/2108.11993/) (2021)
- [3D Kidneys and Kidney Tumor Semantic Segmentation using Boundary-Aware Networks](https://mlsanity.com/paper/1909.06684/) (2019)

## Built on by (most cited first, 4 of 4)

- [UniSeg: A Prompt-driven Universal Segmentation Model as well as A Strong Representation Learner](https://mlsanity.com/paper/2304.03493/) (2023)
- [Omni-Seg: A Scale-aware Dynamic Network for Renal Pathological Image Segmentation](https://mlsanity.com/paper/2206.13632/) (2022)
- [Multi-scale Multi-site Renal Microvascular Structures Segmentation for Whole Slide Imaging in Renal Pathology](https://mlsanity.com/paper/2308.05782/) (2023)
- [Optimal Transport Metric Learning for Feature Alignment in Partially Supervised Segmentation](https://mlsanity.com/paper/2609.19176/) (2026)

## Abstract (arXiv)

Computer-assisted quantitative analysis on Giga-pixel pathology images has provided a new avenue in histology examination. The innovations have been largely focused on cancer pathology (i.e., tumor segmentation and characterization). In non-cancer pathology, the learning algorithms can be asked to examine more comprehensive tissue types simultaneously, as a multi-label setting. The prior arts typically needed to train multiple segmentation networks in order to match the domain-specific knowledge for heterogeneous tissue types (e.g., glomerular tuft, glomerular unit, proximal tubular, distal tubular, peritubular capillaries, and arteries). In this paper, we propose a dynamic single segmentation network (Omni-Seg) that learns to segment multiple tissue types using partially labeled images (i.e., only one tissue type is labeled for each training image) for renal pathology. By learning from ~150,000 patch-wise pathological images from six tissue types, the proposed Omni-Seg network achieved superior segmentation accuracy and less resource consumption when compared to the previous the multiple-network and multi-head design. In the testing stage, the proposed method obtains "completely labeled" tissue segmentation results using only "partially labeled" training images. The source code is available at https://github.com/ddrrnn123/Omni-Seg
