# Dimensionality Reduction of Longitudinal 'Omics Data using Modern Tensor Factorization

arXiv: https://arxiv.org/abs/2111.14159 · HTML: https://mlsanity.com/paper/2111.14159/

## Key facts

- Cited by 1 papers in the map (data through 14 Oct 2026).
- Builds on 1 of its 31 references that are in the map.
- First posted on arXiv 28 Nov 2021.

## Builds on (most cited first, 1 of 1)

- [ROCKET: Exceptionally fast and accurate time series classification using random convolutional kernels](https://mlsanity.com/paper/1910.13051/) (2019)

## Built on by (most cited first, 1 of 1)

- [Projected Tensor-Tensor Products for Efficient Computation of Optimal Multiway Data Representations](https://mlsanity.com/paper/2409.19402/) (2024)

## Abstract (arXiv)

Precision medicine is a clinical approach for disease prevention, detection and treatment, which considers each individual's genetic background, environment and lifestyle. The development of this tailored avenue has been driven by the increased availability of omics methods, large cohorts of temporal samples, and their integration with clinical data. Despite the immense progression, existing computational methods for data analysis fail to provide appropriate solutions for this complex, high-dimensional and longitudinal data. In this work we have developed a new method termed TCAM, a dimensionality reduction technique for multi-way data, that overcomes major limitations when doing trajectory analysis of longitudinal omics data. Using real-world data, we show that TCAM outperforms traditional methods, as well as state-of-the-art tensor-based approaches for longitudinal microbiome data analysis. Moreover, we demonstrate the versatility of TCAM by applying it to several different omics datasets, and the applicability of it as a drop-in replacement within straightforward ML tasks.
