# Sensitivity Analysis of Individual Treatment Effects: A Robust Conformal Inference Approach

arXiv: https://arxiv.org/abs/2111.12161 · HTML: https://mlsanity.com/paper/2111.12161/

## Key facts

- Cited by 62 papers in the map (data through 14 Oct 2026).
- First posted on arXiv 23 Nov 2021.

## Built on by (most cited first, 30 of 62)

- [Uncertainty Quantification over Graph with Conformalized Graph Neural Networks](https://mlsanity.com/paper/2305.14535/) (2023)
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- [Sharp Bounds for Generalized Causal Sensitivity Analysis](https://mlsanity.com/paper/2305.16988/) (2023)
- [Conformal Meta-learners for Predictive Inference of Individual Treatment Effects](https://mlsanity.com/paper/2308.14895/) (2023)
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- [Multi-Source Conformal Inference Under Distribution Shift](https://mlsanity.com/paper/2405.09331/) (2024)
- [Meta-Learners for Partially-Identified Treatment Effects Across Multiple Environments](https://mlsanity.com/paper/2406.02464/) (2024)
- [Causal Fairness under Unobserved Confounding: A Neural Sensitivity Framework](https://mlsanity.com/paper/2311.18460/) (2023)
- [Conformal Counterfactual Inference under Hidden Confounding](https://mlsanity.com/paper/2405.12387/) (2024)
- [Quantifying Aleatoric Uncertainty of the Treatment Effect: A Novel Orthogonal Learner](https://mlsanity.com/paper/2411.03387/) (2024)
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- [Hidden yet quantifiable: A lower bound for confounding strength using randomized trials](https://mlsanity.com/paper/2312.03871/) (2023)
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- [Efficient and Sharp Off-Policy Learning under Unobserved Confounding](https://mlsanity.com/paper/2502.13022/) (2025)
- [Non-exchangeable Conformal Prediction with Optimal Transport: Tackling Distribution Shifts with Unlabeled Data](https://mlsanity.com/paper/2507.10425/) (2025)
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## Abstract (arXiv)

We propose a model-free framework for sensitivity analysis of individual treatment effects (ITEs), building upon ideas from conformal inference. For any unit, our procedure reports the Gamma-value, a number which quantifies the minimum strength of confounding needed to explain away the evidence for ITE. Our approach rests on the reliable predictive inference of counterfactuals and ITEs in situations where the training data is confounded. Under the marginal sensitivity model of Tan (2006), we characterize the shift between the distribution of the observations and that of the counterfactuals. We first develop a general method for predictive inference of test samples from a shifted distribution; we then leverage this to construct covariate-dependent prediction sets for counterfactuals. No matter the value of the shift, these prediction sets (resp. approximately) achieve marginal coverage if the propensity score is known exactly (resp. estimated). We describe a distinct procedure also attaining coverage, however, conditional on the training data. In the latter case, we prove a sharpness result showing that for certain classes of prediction problems, the prediction intervals cannot possibly be tightened. We verify the validity and performance of the new methods via simulation studies and apply them to analyze real datasets.
