# Automatic Semantic Segmentation of the Lumbar Spine: Clinical Applicability in a Multi-parametric and Multi-centre Study on Magnetic Resonance Images

arXiv: https://arxiv.org/abs/2111.08712 · HTML: https://mlsanity.com/paper/2111.08712/

## Key facts

- Cited by 3 papers in the map (data through 14 Oct 2026).
- Builds on 20 of its 70 references that are in the map.
- First posted on arXiv 16 Nov 2021.

## Builds on (most cited first, 20 of 20)

- [U-Net: Convolutional Networks for Biomedical Image Segmentation](https://mlsanity.com/paper/1505.04597/) (2015)
- [Very Deep Convolutional Networks for Large-Scale Image Recognition](https://mlsanity.com/paper/1409.1556/) (2014)
- [Densely Connected Convolutional Networks](https://mlsanity.com/paper/1608.06993/) (2016)
- [Fully Convolutional Networks for Semantic Segmentation](https://mlsanity.com/paper/1411.4038/) (2014)
- [Going Deeper with Convolutions](https://mlsanity.com/paper/1409.4842/) (2014)
- [SegNet: A Deep Convolutional Encoder-Decoder Architecture for Image Segmentation](https://mlsanity.com/paper/1511.00561/) (2015)
- [3D U-Net: Learning Dense Volumetric Segmentation from Sparse Annotation](https://mlsanity.com/paper/1606.06650/) (2016)
- [A Survey on Deep Learning in Medical Image Analysis](https://mlsanity.com/paper/1702.05747/) (2017)
- [Deeply-Supervised Nets](https://mlsanity.com/paper/1409.5185/) (2014)
- [Learning Deconvolution Network for Semantic Segmentation](https://mlsanity.com/paper/1505.04366/) (2015)
- [Attention Gated Networks: Learning to Leverage Salient Regions in Medical Images](https://mlsanity.com/paper/1808.08114/) (2018)
- [MultiResUNet : Rethinking the U-Net Architecture for Multimodal Biomedical Image Segmentation](https://mlsanity.com/paper/1902.04049/) (2019)
- [DeepID3: Face Recognition with Very Deep Neural Networks](https://mlsanity.com/paper/1502.00873/) (2015)
- [The Relative Performance of Ensemble Methods with Deep Convolutional Neural Networks for Image Classification](https://mlsanity.com/paper/1704.01664/) (2017)
- [Automatic Liver and Lesion Segmentation in CT Using Cascaded Fully Convolutional Neural Networks and 3D Conditional Random Fields](https://mlsanity.com/paper/1610.02177/) (2016)
- [SegNet: A Deep Convolutional Encoder-Decoder Architecture for Robust Semantic Pixel-Wise Labelling](https://mlsanity.com/paper/1505.07293/) (2015)
- [QuickNAT: A Fully Convolutional Network for Quick and Accurate Segmentation of Neuroanatomy](https://mlsanity.com/paper/1801.04161/) (2018)
- [Object Detection from Scratch with Deep Supervision](https://mlsanity.com/paper/1809.09294/) (2018)
- [Skin Lesion Segmentation: U-Nets versus Clustering](https://mlsanity.com/paper/1710.01248/) (2017)
- [Medical imaging data structure extended to multiple modalities and anatomical regions](https://mlsanity.com/paper/2010.00434/) (2020)

## Built on by (most cited first, 3 of 3)

- [SPINEPS -- Automatic Whole Spine Segmentation of T2-weighted MR images using a Two-Phase Approach to Multi-class Semantic and Instance Segmentation](https://mlsanity.com/paper/2402.16368/) (2024)
- [RobustEMD: Domain Robust Matching for Cross-domain Few-shot Medical Image Segmentation](https://mlsanity.com/paper/2410.01110/) (2024)
- [Anatomy-Aware Text-Visual Fusion with Dual-Perspective Prompts for Fine-Grained Lumbar Spine Segmentation](https://mlsanity.com/paper/2504.03476/) (2025)

## Abstract (arXiv)

One of the major difficulties in medical image segmentation is the high variability of these images, which is caused by their origin (multi-centre), the acquisition protocols (multi-parametric), as well as the variability of human anatomy, the severity of the illness, the effect of age and gender, among others. The problem addressed in this work is the automatic semantic segmentation of lumbar spine Magnetic Resonance images using convolutional neural networks. The purpose is to assign a class label to each pixel of an image. Classes were defined by radiologists and correspond to different structural elements like vertebrae, intervertebral discs, nerves, blood vessels, and other tissues. The proposed network topologies are variants of the U-Net architecture. Several complementary blocks were used to define the variants: Three types of convolutional blocks, spatial attention models, deep supervision and multilevel feature extractor. This document describes the topologies and analyses the results of the neural network designs that obtained the most accurate segmentations. Several of the proposed designs outperform the standard U-Net used as baseline, especially when used in ensembles where the output of multiple neural networks is combined according to different strategies.