# Evaluation of Deep Learning Topcoders Method for Neuron Individualization in Histological Macaque Brain Section

arXiv: https://arxiv.org/abs/2111.05789 · HTML: https://mlsanity.com/paper/2111.05789/

## Key facts

- Cited by 1 papers in the map (data through 14 Oct 2026).
- Builds on 6 of its 15 references that are in the map.
- First posted on arXiv 10 Nov 2021.

## Builds on (most cited first, 6 of 6)

- [Deep Residual Learning for Image Recognition](https://mlsanity.com/paper/1512.03385/) (2015)
- [Densely Connected Convolutional Networks](https://mlsanity.com/paper/1608.06993/) (2016)
- [EfficientNet: Rethinking Model Scaling for Convolutional Neural Networks](https://mlsanity.com/paper/1905.11946/) (2019)
- [Inception-v4, Inception-ResNet and the Impact of Residual Connections on Learning](https://mlsanity.com/paper/1602.07261/) (2016)
- [Dual Path Networks](https://mlsanity.com/paper/1707.01629/) (2017)
- [A Deep Learning Algorithm for One-step Contour Aware Nuclei Segmentation of Histopathological Images](https://mlsanity.com/paper/1803.02786/) (2018)

## Built on by (most cited first, 1 of 1)

- [A General Deep Learning framework for Neuron Instance Segmentation based on Efficient UNet and Morphological Post-processing](https://mlsanity.com/paper/2202.08682/) (2022)

## Abstract (arXiv)

Cell individualization has a vital role in digital pathology image analysis. Deep Learning is considered as an efficient tool for instance segmentation tasks, including cell individualization. However, the precision of the Deep Learning model relies on massive unbiased dataset and manual pixel-level annotations, which is labor intensive. Moreover, most applications of Deep Learning have been developed for processing oncological data. To overcome these challenges, i) we established a pipeline to synthesize pixel-level labels with only point annotations provided; ii) we tested an ensemble Deep Learning algorithm to perform cell individualization on neurological data. Results suggest that the proposed method successfully segments neuronal cells in both object-level and pixel-level, with an average detection accuracy of 0.93.