# M2MRF: Many-to-Many Reassembly of Features for Tiny Lesion Segmentation in Fundus Images

arXiv: https://arxiv.org/abs/2111.00193 · HTML: https://mlsanity.com/paper/2111.00193/

## Key facts

- Cited by 2 papers in the map (data through 14 Oct 2026).
- Builds on 33 of its 51 references that are in the map.
- First posted on arXiv 30 Oct 2021.

## Builds on (most cited first, 30 of 33)

- [U-Net: Convolutional Networks for Biomedical Image Segmentation](https://mlsanity.com/paper/1505.04597/) (2015)
- [Swin Transformer: Hierarchical Vision Transformer using Shifted Windows](https://mlsanity.com/paper/2103.14030/) (2021)
- [Fully Convolutional Networks for Semantic Segmentation](https://mlsanity.com/paper/1411.4038/) (2014)
- [The Cityscapes Dataset for Semantic Urban Scene Understanding](https://mlsanity.com/paper/1604.01685/) (2016)
- [DeepLab: Semantic Image Segmentation with Deep Convolutional Nets, Atrous Convolution, and Fully Connected CRFs](https://mlsanity.com/paper/1606.00915/) (2016)
- [Encoder-Decoder with Atrous Separable Convolution for Semantic Image Segmentation](https://mlsanity.com/paper/1802.02611/) (2018)
- [Pyramid Scene Parsing Network](https://mlsanity.com/paper/1612.01105/) (2016)
- [V-Net: Fully Convolutional Neural Networks for Volumetric Medical Image Segmentation](https://mlsanity.com/paper/1606.04797/) (2016)
- [Visualizing and Understanding Convolutional Networks](https://mlsanity.com/paper/1311.2901/) (2013)
- [Deformable Convolutional Networks](https://mlsanity.com/paper/1703.06211/) (2017)
- [SegNet: A Deep Convolutional Encoder-Decoder Architecture for Image Segmentation](https://mlsanity.com/paper/1511.00561/) (2015)
- [Deep High-Resolution Representation Learning for Visual Recognition](https://mlsanity.com/paper/1908.07919/) (2019)
- [Deep High-Resolution Representation Learning for Human Pose Estimation](https://mlsanity.com/paper/1902.09212/) (2019)
- [Dual Attention Network for Scene Segmentation](https://mlsanity.com/paper/1809.02983/) (2018)
- [Striving for Simplicity: The All Convolutional Net](https://mlsanity.com/paper/1412.6806/) (2014)
- [CCNet: Criss-Cross Attention for Semantic Segmentation](https://mlsanity.com/paper/1811.11721/) (2018)
- [Holistically-Nested Edge Detection](https://mlsanity.com/paper/1504.06375/) (2015)
- [UNet++: Redesigning Skip Connections to Exploit Multiscale Features in Image Segmentation](https://mlsanity.com/paper/1912.05074/) (2019)
- [Twins: Revisiting the Design of Spatial Attention in Vision Transformers](https://mlsanity.com/paper/2104.13840/) (2021)
- [CSWin Transformer: A General Vision Transformer Backbone with Cross-Shaped Windows](https://mlsanity.com/paper/2107.00652/) (2021)
- [Learning Deconvolution Network for Semantic Segmentation](https://mlsanity.com/paper/1505.04366/) (2015)
- [Disentangled Non-Local Neural Networks](https://mlsanity.com/paper/2006.06668/) (2020)
- [CARAFE: Content-Aware ReAssembly of FEatures](https://mlsanity.com/paper/1905.02188/) (2019)
- [Strip Pooling: Rethinking Spatial Pooling for Scene Parsing](https://mlsanity.com/paper/2003.13328/) (2020)
- [Indices Matter: Learning to Index for Deep Image Matting](https://mlsanity.com/paper/1908.00672/) (2019)
- [Joint Optic Disc and Cup Segmentation Based on Multi-label Deep Network and Polar Transformation](https://mlsanity.com/paper/1801.00926/) (2018)
- [Cars Can't Fly up in the Sky: Improving Urban-Scene Segmentation via Height-driven Attention Networks](https://mlsanity.com/paper/2003.05128/) (2020)
- [GFF: Gated Fully Fusion for Semantic Segmentation](https://mlsanity.com/paper/1904.01803/) (2019)
- [Learning Affinity-Aware Upsampling for Deep Image Matting](https://mlsanity.com/paper/2011.14288/) (2020)
- [LIP: Local Importance-based Pooling](https://mlsanity.com/paper/1908.04156/) (2019)

## Built on by (most cited first, 2 of 2)

- [Bi-VLGM : Bi-Level Class-Severity-Aware Vision-Language Graph Matching for Text Guided Medical Image Segmentation](https://mlsanity.com/paper/2305.12231/) (2023)
- [Coarse Retinal Lesion Annotations Refinement via Prototypical Learning](https://mlsanity.com/paper/2208.14294/) (2022)

## Abstract (arXiv)

Feature reassembly is an essential component in modern CNN-based segmentation approaches, which includes feature downsampling and upsampling operators. Existing operators reassemble multiple features from a small predefined region into one for each target location independently. This may result in loss of spatial information, which could vanish activations caused by tiny lesions particularly when they cluster together. In this paper, we propose a many-to-many reassembly of features (M2MRF). It reassembles features in a dimension-reduced feature space and simultaneously aggregates multiple features inside a large predefined region into multiple target features. In this way, long range spatial dependencies are captured to maintain activations on tiny lesions. Experimental results on two lesion segmentation benchmarks, i.e. DDR and IDRiD, show that (1) our M2MRF outperforms existing feature reassembly operators; (2) equipped with our M2MRF, the HRNetv2 is able to achieve significant better performance to CNN-based segmentation methods and competitive even better performance to two recent transformer-based segmentation methods. Our code is made publicly available at https://github.com/CVIU-CSU/M2MRF-Lesion-Segmentation.