# Fetal MRI by robust deep generative prior reconstruction and diffeomorphic registration: application to gestational age prediction

arXiv: https://arxiv.org/abs/2111.00102 · HTML: https://mlsanity.com/paper/2111.00102/

## Key facts

- No citing papers in the map yet (data through 14 Oct 2026).
- Builds on 16 of its 47 references that are in the map.
- First posted on arXiv 29 Oct 2021.

## Builds on (most cited first, 16 of 16)

- [Deep Residual Learning for Image Recognition](https://mlsanity.com/paper/1512.03385/) (2015)
- [Batch Normalization: Accelerating Deep Network Training by Reducing Internal Covariate Shift](https://mlsanity.com/paper/1502.03167/) (2015)
- [Densely Connected Convolutional Networks](https://mlsanity.com/paper/1608.06993/) (2016)
- [MobileNetV2: Inverted Residuals and Linear Bottlenecks](https://mlsanity.com/paper/1801.04381/) (2018)
- [Going Deeper with Convolutions](https://mlsanity.com/paper/1409.4842/) (2014)
- [ShuffleNet: An Extremely Efficient Convolutional Neural Network for Mobile Devices](https://mlsanity.com/paper/1707.01083/) (2017)
- [Deep Learning Techniques for Inverse Problems in Imaging](https://mlsanity.com/paper/2005.06001/) (2020)
- [Deep Decoder: Concise Image Representations from Untrained Non-convolutional Networks](https://mlsanity.com/paper/1810.03982/) (2018)
- [Predicting brain age with deep learning from raw imaging data results in a reliable and heritable biomarker](https://mlsanity.com/paper/1612.02572/) (2016)
- [Real-time Deep Pose Estimation with Geodesic Loss for Image-to-Template Rigid Registration](https://mlsanity.com/paper/1803.05982/) (2018)
- [Deformable Slice-to-Volume Registration for Motion Correction in Fetal Body MRI](https://mlsanity.com/paper/1906.08827/) (2019)
- [Slice-to-volume medical image registration: a survey](https://mlsanity.com/paper/1702.01636/) (2017)
- [3D Reconstruction in Canonical Co-ordinate Space from Arbitrarily Oriented 2D Images](https://mlsanity.com/paper/1709.06341/) (2017)
- [A Lagrangian Gauss-Newton-Krylov Solver for Mass- and Intensity-Preserving Diffeomorphic Image Registration](https://mlsanity.com/paper/1703.04446/) (2017)
- [Deep Predictive Motion Tracking in Magnetic Resonance Imaging: Application to Fetal Imaging](https://mlsanity.com/paper/1909.11625/) (2019)
- [PVR: Patch-to-Volume Reconstruction for Large Area Motion Correction of Fetal MRI](https://mlsanity.com/paper/1611.07289/) (2016)

## Abstract (arXiv)

Magnetic resonance imaging of whole fetal body and placenta is limited by different sources of motion affecting the womb. Usual scanning techniques employ single-shot multi-slice sequences where anatomical information in different slices may be subject to different deformations, contrast variations or artifacts. Volumetric reconstruction formulations have been proposed to correct for these factors, but they must accommodate a non-homogeneous and non-isotropic sampling, so regularization becomes necessary. Thus, in this paper we propose a deep generative prior for robust volumetric reconstructions integrated with a diffeomorphic volume to slice registration method. Experiments are performed to validate our contributions and compare with a state of the art method in a cohort of 72 fetal datasets in the range of 20-36 weeks gestational age. Results suggest improved image resolution and more accurate prediction of gestational age at scan when comparing to a state of the art reconstruction method. In addition, gestational age prediction results from our volumetric reconstructions compare favourably with existing brain-based approaches, with boosted accuracy when integrating information of organs other than the brain. Namely, a mean absolute error of 0.618 weeks (R2=0.958) is achieved when combining fetal brain and trunk information.