# Survival-oriented embeddings for improving accessibility to complex data structures

arXiv: https://arxiv.org/abs/2110.11303 · HTML: https://mlsanity.com/paper/2110.11303/

## Key facts

- No citing papers in the map yet (data through 14 Oct 2026).
- Builds on 14 of its 28 references that are in the map.
- First posted on arXiv 21 Oct 2021.

## Builds on (most cited first, 14 of 14)

- [Deep Residual Learning for Image Recognition](https://mlsanity.com/paper/1512.03385/) (2015)
- [Adam: A Method for Stochastic Optimization](https://mlsanity.com/paper/1412.6980/) (2014)
- [Auto-Encoding Variational Bayes](https://mlsanity.com/paper/1312.6114/) (2013)
- [Grad-CAM++: Improved Visual Explanations for Deep Convolutional Networks](https://mlsanity.com/paper/1710.11063/) (2017)
- [Deep Variational Information Bottleneck](https://mlsanity.com/paper/1612.00410/) (2016)
- [DeepSurv: Personalized Treatment Recommender System Using A Cox Proportional Hazards Deep Neural Network](https://mlsanity.com/paper/1606.00931/) (2016)
- [nnU-Net: Self-adapting Framework for U-Net-Based Medical Image Segmentation](https://mlsanity.com/paper/1809.10486/) (2018)
- [Grad-CAM: Why did you say that?](https://mlsanity.com/paper/1611.07450/) (2016)
- [A Scalable Discrete-Time Survival Model for Neural Networks](https://mlsanity.com/paper/1805.00917/) (2018)
- [Deep learning cardiac motion analysis for human survival prediction](https://mlsanity.com/paper/1810.03382/) (2018)
- [Deep Learning for Patient-Specific Kidney Graft Survival Analysis](https://mlsanity.com/paper/1705.10245/) (2017)
- [Semi-Structured Deep Piecewise Exponential Models](https://mlsanity.com/paper/2011.05824/) (2020)
- [A General Machine Learning Framework for Survival Analysis](https://mlsanity.com/paper/2006.15442/) (2020)
- [CNN-based Survival Model for Pancreatic Ductal Adenocarcinoma in Medical Imaging](https://mlsanity.com/paper/1906.10729/) (2019)

## Abstract (arXiv)

Deep learning excels in the analysis of unstructured data and recent advancements allow to extend these techniques to survival analysis. In the context of clinical radiology, this enables, e.g., to relate unstructured volumetric images to a risk score or a prognosis of life expectancy and support clinical decision making. Medical applications are, however, associated with high criticality and consequently, neither medical personnel nor patients do usually accept black box models as reason or basis for decisions. Apart from averseness to new technologies, this is due to missing interpretability, transparency and accountability of many machine learning methods. We propose a hazard-regularized variational autoencoder that supports straightforward interpretation of deep neural architectures in the context of survival analysis, a field highly relevant in healthcare. We apply the proposed approach to abdominal CT scans of patients with liver tumors and their corresponding survival times.
