# Algorithm Fairness in AI for Medicine and Healthcare

arXiv: https://arxiv.org/abs/2110.00603 · HTML: https://mlsanity.com/paper/2110.00603/

## Key facts

- Cited by 21 papers in the map (data through 14 Oct 2026).
- Builds on 125 of its 325 references that are in the map.
- First posted on arXiv 1 Oct 2021.

## Builds on (most cited first, 30 of 125)

- [A Simple Framework for Contrastive Learning of Visual Representations](https://mlsanity.com/paper/2002.05709/) (2020)
- [Communication-Efficient Learning of Deep Networks from Decentralized Data](https://mlsanity.com/paper/1602.05629/) (2016)
- [Emerging Properties in Self-Supervised Vision Transformers](https://mlsanity.com/paper/2104.14294/) (2021)
- [Grad-CAM: Visual Explanations from Deep Networks via Gradient-based Localization](https://mlsanity.com/paper/1610.02391/) (2016)
- [A Unified Approach to Interpreting Model Predictions](https://mlsanity.com/paper/1705.07874/) (2017)
- [Axiomatic Attribution for Deep Networks](https://mlsanity.com/paper/1703.01365/) (2017)
- [Federated Optimization in Heterogeneous Networks](https://mlsanity.com/paper/1812.06127/) (2018)
- [Deep Inside Convolutional Networks: Visualising Image Classification Models and Saliency Maps](https://mlsanity.com/paper/1312.6034/) (2013)
- [Visualizing and Understanding Convolutional Networks](https://mlsanity.com/paper/1311.2901/) (2013)
- [Equality of Opportunity in Supervised Learning](https://mlsanity.com/paper/1610.02413/) (2016)
- [Unsupervised Domain Adaptation by Backpropagation](https://mlsanity.com/paper/1409.7495/) (2014)
- [Federated Learning: Strategies for Improving Communication Efficiency](https://mlsanity.com/paper/1610.05492/) (2016)
- [Attention U-Net: Learning Where to Look for the Pancreas](https://mlsanity.com/paper/1804.03999/) (2018)
- [CheXpert: A Large Chest Radiograph Dataset with Uncertainty Labels and Expert Comparison](https://mlsanity.com/paper/1901.07031/) (2019)
- [Distributionally Robust Neural Networks for Group Shifts: On the Importance of Regularization for Worst-Case Generalization](https://mlsanity.com/paper/1911.08731/) (2019)
- [Sanity Checks for Saliency Maps](https://mlsanity.com/paper/1810.03292/) (2018)
- [Federated Learning with Non-IID Data](https://mlsanity.com/paper/1806.00582/) (2018)
- [Attention-based Deep Multiple Instance Learning](https://mlsanity.com/paper/1802.04712/) (2018)
- [Challenging Common Assumptions in the Unsupervised Learning of Disentangled Representations](https://mlsanity.com/paper/1811.12359/) (2018)
- [InfoGAN: Interpretable Representation Learning by Information Maximizing Generative Adversarial Nets](https://mlsanity.com/paper/1606.03657/) (2016)
- [Do We Really Need to Access the Source Data? Source Hypothesis Transfer for Unsupervised Domain Adaptation](https://mlsanity.com/paper/2002.08546/) (2020)
- [Towards Federated Learning at Scale: System Design](https://mlsanity.com/paper/1902.01046/) (2019)
- [Data Efficient and Weakly Supervised Computational Pathology on Whole Slide Images](https://mlsanity.com/paper/2004.09666/) (2020)
- [Mitigating Unwanted Biases with Adversarial Learning](https://mlsanity.com/paper/1801.07593/) (2018)
- [The Future of Digital Health with Federated Learning](https://mlsanity.com/paper/2003.08119/) (2020)
- [Disentangling by Factorising](https://mlsanity.com/paper/1802.05983/) (2018)
- [A Reductions Approach to Fair Classification](https://mlsanity.com/paper/1803.02453/) (2018)
- [Inherent Trade-Offs in the Fair Determination of Risk Scores](https://mlsanity.com/paper/1609.05807/) (2016)
- [A systematic study of the class imbalance problem in convolutional neural networks](https://mlsanity.com/paper/1710.05381/) (2017)
- [Deep Gradient Compression: Reducing the Communication Bandwidth for Distributed Training](https://mlsanity.com/paper/1712.01887/) (2017)

## Built on by (most cited first, 21 of 21)

- [MEDFAIR: Benchmarking Fairness for Medical Imaging](https://mlsanity.com/paper/2210.01725/) (2022)
- [Guidelines and Evaluation of Clinical Explainable AI in Medical Image Analysis](https://mlsanity.com/paper/2202.10553/) (2022)
- [Fair Machine Unlearning: Data Removal while Mitigating Disparities](https://mlsanity.com/paper/2307.14754/) (2023)
- [A Review of Causality for Learning Algorithms in Medical Image Analysis](https://mlsanity.com/paper/2206.05498/) (2022)
- [Improving Fairness in AI Models on Electronic Health Records: The Case for Federated Learning Methods](https://mlsanity.com/paper/2305.11386/) (2023)
- [A Review of the Role of Causality in Developing Trustworthy AI Systems](https://mlsanity.com/paper/2302.06975/) (2023)
- [Mitigating Health Disparities in EHR via Deconfounder](https://mlsanity.com/paper/2210.15901/) (2022)
- [Fairness Evaluation in Text Classification: Machine Learning Practitioner Perspectives of Individual and Group Fairness](https://mlsanity.com/paper/2303.00673/) (2023)
- [Three Applications of Conformal Prediction for Rating Breast Density in Mammography](https://mlsanity.com/paper/2206.12008/) (2022)
- [Imputation Strategies Under Clinical Presence: Impact on Algorithmic Fairness](https://mlsanity.com/paper/2208.06648/) (2022)
- [Enhancing Fairness of Visual Attribute Predictors](https://mlsanity.com/paper/2207.05727/) (2022)
- [A Survey on Preserving Fairness Guarantees in Changing Environments](https://mlsanity.com/paper/2211.07530/) (2022)
- [Out-of-distribution Reject Option Method for Dataset Shift Problem in Early Disease Onset Prediction](https://mlsanity.com/paper/2405.19864/) (2024)
- [Ethical considerations of use of hold-out sets in clinical prediction model management](https://mlsanity.com/paper/2406.03161/) (2024)
- [Fair Machine Learning in Healthcare: A Review](https://mlsanity.com/paper/2206.14397/) (2022)
- [Identifying and Combating Bias in Segmentation Networks by leveraging multiple resolutions](https://mlsanity.com/paper/2206.14919/) (2022)
- [Ex-Ante Assessment of Discrimination in Dataset](https://mlsanity.com/paper/2208.07918/) (2022)
- [Echoes of Biases: How Stigmatizing Language Affects AI Performance](https://mlsanity.com/paper/2305.10201/) (2023)
- [Learning Unbiased Image Segmentation: A Case Study with Plain Knee Radiographs](https://mlsanity.com/paper/2308.04356/) (2023)
- [Beyond Fairness: Age-Harmless Parkinson's Detection via Voice](https://mlsanity.com/paper/2309.13292/) (2023)
- [Causal Transfer in Medical Image Analysis](https://mlsanity.com/paper/2603.24388/) (2026)

## Abstract (arXiv)

In the current development and deployment of many artificial intelligence (AI) systems in healthcare, algorithm fairness is a challenging problem in delivering equitable care. Recent evaluation of AI models stratified across race sub-populations have revealed inequalities in how patients are diagnosed, given treatments, and billed for healthcare costs. In this perspective article, we summarize the intersectional field of fairness in machine learning through the context of current issues in healthcare, outline how algorithmic biases (e.g. - image acquisition, genetic variation, intra-observer labeling variability) arise in current clinical workflows and their resulting healthcare disparities. Lastly, we also review emerging technology for mitigating bias via federated learning, disentanglement, and model explainability, and their role in AI-SaMD development.
