# Sample-Efficient Safety Assurances using Conformal Prediction

arXiv: https://arxiv.org/abs/2109.14082 · HTML: https://mlsanity.com/paper/2109.14082/

## Key facts

- Cited by 41 papers in the map (data through 14 Oct 2026).
- Builds on 16 of its 50 references that are in the map.
- First posted on arXiv 28 Sep 2021.

## Builds on (most cited first, 16 of 16)

- [nuScenes: A multimodal dataset for autonomous driving](https://mlsanity.com/paper/1903.11027/) (2019)
- [Conformal Prediction Under Covariate Shift](https://mlsanity.com/paper/1904.06019/) (2019)
- [Uncertainty Sets for Image Classifiers using Conformal Prediction](https://mlsanity.com/paper/2009.14193/) (2020)
- [Performative Prediction](https://mlsanity.com/paper/2002.06673/) (2020)
- [Dex-Net 2.0: Deep Learning to Plan Robust Grasps with Synthetic Point Clouds and Analytic Grasp Metrics](https://mlsanity.com/paper/1703.09312/) (2017)
- [Robust Validation: Confident Predictions Even When Distributions Shift](https://mlsanity.com/paper/2008.04267/) (2020)
- [Multi-view Self-supervised Deep Learning for 6D Pose Estimation in the Amazon Picking Challenge](https://mlsanity.com/paper/1609.09475/) (2016)
- [Online Multivalid Learning: Means, Moments, and Prediction Intervals](https://mlsanity.com/paper/2101.01739/) (2021)
- [Improving Conditional Coverage via Orthogonal Quantile Regression](https://mlsanity.com/paper/2106.00394/) (2021)
- [Real-time Out-of-distribution Detection in Learning-Enabled Cyber-Physical Systems](https://mlsanity.com/paper/2001.10494/) (2020)
- [Analysis and Observations from the First Amazon Picking Challenge](https://mlsanity.com/paper/1601.05484/) (2016)
- [Dex-Net 3.0: Computing Robust Robot Vacuum Suction Grasp Targets in Point Clouds using a New Analytic Model and Deep Learning](https://mlsanity.com/paper/1709.06670/) (2017)
- [Team Delft's Robot Winner of the Amazon Picking Challenge 2016](https://mlsanity.com/paper/1610.05514/) (2016)
- [Reactive motion planning with probabilistic safety guarantees](https://mlsanity.com/paper/2011.03590/) (2020)
- [A Summary of Team MIT's Approach to the Amazon Picking Challenge 2015](https://mlsanity.com/paper/1604.03639/) (2016)
- [Guaranteed Model-Based Fault Detection in Cyber-Physical Systems: A Model Invalidation Approach](https://mlsanity.com/paper/1609.05921/) (2016)

## Built on by (most cited first, 30 of 41)

- [Robots That Ask For Help: Uncertainty Alignment for Large Language Model Planners](https://mlsanity.com/paper/2307.01928/) (2023)
- [Unpacking Failure Modes of Generative Policies: Runtime Monitoring of Consistency and Progress](https://mlsanity.com/paper/2410.04640/) (2024)
- [Real-Time Anomaly Detection and Reactive Planning with Large Language Models](https://mlsanity.com/paper/2407.08735/) (2024)
- [Conformal Prediction Under Feedback Covariate Shift for Biomolecular Design](https://mlsanity.com/paper/2202.03613/) (2022)
- [Conformal Decision Theory: Safe Autonomous Decisions from Imperfect Predictions](https://mlsanity.com/paper/2310.05921/) (2023)
- [A System-Level View on Out-of-Distribution Data in Robotics](https://mlsanity.com/paper/2212.14020/) (2022)
- [Object Pose Estimation with Statistical Guarantees: Conformal Keypoint Detection and Geometric Uncertainty Propagation](https://mlsanity.com/paper/2303.12246/) (2023)
- [Conformal Prediction Regions for Time Series using Linear Complementarity Programming](https://mlsanity.com/paper/2304.01075/) (2023)
- [Copula Conformal Prediction for Multi-step Time Series Forecasting](https://mlsanity.com/paper/2212.03281/) (2022)
- [Adaptive Bounding Box Uncertainties via Two-Step Conformal Prediction](https://mlsanity.com/paper/2403.07263/) (2024)
- [How Generalizable Is My Behavior Cloning Policy? A Statistical Approach to Trustworthy Performance Evaluation](https://mlsanity.com/paper/2405.05439/) (2024)
- [Distributionally Robust Statistical Verification with Imprecise Neural Networks](https://mlsanity.com/paper/2308.14815/) (2023)
- [Conformal Methods for Quantifying Uncertainty in Spatiotemporal Data: A Survey](https://mlsanity.com/paper/2209.03580/) (2022)
- [Conformalized Interactive Imitation Learning: Handling Expert Shift and Intermittent Feedback](https://mlsanity.com/paper/2410.08852/) (2024)
- [Data-Driven Reachability Analysis of Stochastic Dynamical Systems with Conformal Inference](https://mlsanity.com/paper/2309.09187/) (2023)
- [Cocoon: Robust Multi-Modal Perception with Uncertainty-Aware Sensor Fusion](https://mlsanity.com/paper/2410.12592/) (2024)
- [Conformal Policy Learning for Sensorimotor Control Under Distribution Shifts](https://mlsanity.com/paper/2311.01457/) (2023)
- [Conformalized Teleoperation: Confidently Mapping Human Inputs to High-Dimensional Robot Actions](https://mlsanity.com/paper/2406.07767/) (2024)
- [SafeMimic: Towards Safe and Autonomous Human-to-Robot Imitation for Mobile Manipulation](https://mlsanity.com/paper/2506.15847/) (2025)
- [Conformal Policy Control](https://mlsanity.com/paper/2603.02196/) (2026)
- [Bridging Dimensions: Confident Reachability for High-Dimensional Controllers](https://mlsanity.com/paper/2311.04843/) (2023)
- [Hypergraph-Transformer (HGT) for Interactive Event Prediction in Laparoscopic and Robotic Surgery](https://mlsanity.com/paper/2402.01974/) (2024)
- [Multi-Modal Conformal Prediction Regions with Simple Structures by Optimizing Convex Shape Templates](https://mlsanity.com/paper/2312.07434/) (2023)
- [Recursively Feasible Shrinking-Horizon MPC in Dynamic Environments with Conformal Prediction Guarantees](https://mlsanity.com/paper/2405.10875/) (2024)
- [Statistical Reachability Analysis of Stochastic Cyber-Physical Systems under Distribution Shift](https://mlsanity.com/paper/2407.11609/) (2024)
- [Out of Distribution Detection via Domain-Informed Gaussian Process State Space Models](https://mlsanity.com/paper/2309.06655/) (2023)
- [CommCP: Efficient Multi-Agent Coordination via LLM-Based Communication with Conformal Prediction](https://mlsanity.com/paper/2602.06038/) (2026)
- [Probabilistic Symmetry for Multi-Agent Dynamics](https://mlsanity.com/paper/2205.01927/) (2022)
- [Air Traffic Controller Workload Level Prediction using Conformalized Dynamical Graph Learning](https://mlsanity.com/paper/2307.10559/) (2023)
- [Failure Forecasting Boosts Robustness of Sim2Real Rhythmic Insertion Policies](https://mlsanity.com/paper/2507.06519/) (2025)

## Abstract (arXiv)

When deploying machine learning models in high-stakes robotics applications, the ability to detect unsafe situations is crucial. Early warning systems can provide alerts when an unsafe situation is imminent (in the absence of corrective action). To reliably improve safety, these warning systems should have a provable false negative rate; i.e. of the situations that are unsafe, fewer than ε will occur without an alert. In this work, we present a framework that combines a statistical inference technique known as conformal prediction with a simulator of robot/environment dynamics, in order to tune warning systems to provably achieve an ε false negative rate using as few as 1/ε data points. We apply our framework to a driver warning system and a robotic grasping application, and empirically demonstrate guaranteed false negative rate while also observing low false detection (positive) rate.
