# Federated Learning for Privacy-Preserving Open Innovation Future on Digital Health

arXiv: https://arxiv.org/abs/2108.10761 · HTML: https://mlsanity.com/paper/2108.10761/

## Key facts

- Cited by 8 papers in the map (data through 14 Oct 2026).
- Builds on 35 of its 63 references that are in the map.
- First posted on arXiv 24 Aug 2021.

## Builds on (most cited first, 30 of 35)

- [Distilling the Knowledge in a Neural Network](https://mlsanity.com/paper/1503.02531/) (2015)
- [Communication-Efficient Learning of Deep Networks from Decentralized Data](https://mlsanity.com/paper/1602.05629/) (2016)
- [Advances and Open Problems in Federated Learning](https://mlsanity.com/paper/1912.04977/) (2019)
- [Federated Learning: Strategies for Improving Communication Efficiency](https://mlsanity.com/paper/1610.05492/) (2016)
- [Adaptive Federated Optimization](https://mlsanity.com/paper/2003.00295/) (2020)
- [Deep Leakage from Gradients](https://mlsanity.com/paper/1906.08935/) (2019)
- [How To Backdoor Federated Learning](https://mlsanity.com/paper/1807.00459/) (2018)
- [Inverting Gradients -- How easy is it to break privacy in federated learning?](https://mlsanity.com/paper/2003.14053/) (2020)
- [Ensemble Distillation for Robust Model Fusion in Federated Learning](https://mlsanity.com/paper/2006.07242/) (2020)
- [The Future of Digital Health with Federated Learning](https://mlsanity.com/paper/2003.08119/) (2020)
- [Federated Learning with Personalization Layers](https://mlsanity.com/paper/1912.00818/) (2019)
- [An Efficient Framework for Clustered Federated Learning](https://mlsanity.com/paper/2006.04088/) (2020)
- [Clustered Federated Learning: Model-Agnostic Distributed Multi-Task Optimization under Privacy Constraints](https://mlsanity.com/paper/1910.01991/) (2019)
- [Local Model Poisoning Attacks to Byzantine-Robust Federated Learning](https://mlsanity.com/paper/1911.11815/) (2019)
- [FedMD: Heterogenous Federated Learning via Model Distillation](https://mlsanity.com/paper/1910.03581/) (2019)
- [Federated Machine Learning: Concept and Applications](https://mlsanity.com/paper/1902.04885/) (2019)
- [iDLG: Improved Deep Leakage from Gradients](https://mlsanity.com/paper/2001.02610/) (2020)
- [Adaptive Personalized Federated Learning](https://mlsanity.com/paper/2003.13461/) (2020)
- [Think Locally, Act Globally: Federated Learning with Local and Global Representations](https://mlsanity.com/paper/2001.01523/) (2020)
- [Three Approaches for Personalization with Applications to Federated Learning](https://mlsanity.com/paper/2002.10619/) (2020)
- [Attack of the Tails: Yes, You Really Can Backdoor Federated Learning](https://mlsanity.com/paper/2007.05084/) (2020)
- [A Little Is Enough: Circumventing Defenses For Distributed Learning](https://mlsanity.com/paper/1902.06156/) (2019)
- [Communication-Efficient On-Device Machine Learning: Federated Distillation and Augmentation under Non-IID Private Data](https://mlsanity.com/paper/1811.11479/) (2018)
- [Privacy-preserving Federated Brain Tumour Segmentation](https://mlsanity.com/paper/1910.00962/) (2019)
- [Multi-Institutional Deep Learning Modeling Without Sharing Patient Data: A Feasibility Study on Brain Tumor Segmentation](https://mlsanity.com/paper/1810.04304/) (2018)
- [Deep EHR: A Survey of Recent Advances in Deep Learning Techniques for Electronic Health Record (EHR) Analysis](https://mlsanity.com/paper/1706.03446/) (2017)
- [Stronger Data Poisoning Attacks Break Data Sanitization Defenses](https://mlsanity.com/paper/1811.00741/) (2018)
- [Multi-Center Federated Learning: Clients Clustering for Better Personalization](https://mlsanity.com/paper/2108.08647/) (2021)
- [Learning to Detect Malicious Clients for Robust Federated Learning](https://mlsanity.com/paper/2002.00211/) (2020)
- [Lifelong Federated Reinforcement Learning: A Learning Architecture for Navigation in Cloud Robotic Systems](https://mlsanity.com/paper/1901.06455/) (2019)

## Built on by (most cited first, 8 of 8)

- [Federated Learning from Pre-Trained Models: A Contrastive Learning Approach](https://mlsanity.com/paper/2209.10083/) (2022)
- [Prompt Federated Learning for Weather Forecasting: Toward Foundation Models on Meteorological Data](https://mlsanity.com/paper/2301.09152/) (2023)
- [On the Convergence of Clustered Federated Learning](https://mlsanity.com/paper/2202.06187/) (2022)
- [Personalized Federated Learning With Graph](https://mlsanity.com/paper/2203.00829/) (2022)
- [Dual Personalization on Federated Recommendation](https://mlsanity.com/paper/2301.08143/) (2023)
- [Sequential Diagnosis Prediction with Transformer and Ontological Representation](https://mlsanity.com/paper/2109.03069/) (2021)
- [Breaching FedMD: Image Recovery via Paired-Logits Inversion Attack](https://mlsanity.com/paper/2304.11436/) (2023)
- [FedBKD: Distilled Federated Learning to Embrace Gerneralization and Personalization on Non-IID Data](https://mlsanity.com/paper/2506.20245/) (2025)

## Abstract (arXiv)

Privacy protection is an ethical issue with broad concern in Artificial Intelligence (AI). Federated learning is a new machine learning paradigm to learn a shared model across users or organisations without direct access to the data. It has great potential to be the next-general AI model training framework that offers privacy protection and therefore has broad implications for the future of digital health and healthcare informatics. Implementing an open innovation framework in the healthcare industry, namely open health, is to enhance innovation and creative capability of health-related organisations by building a next-generation collaborative framework with partner organisations and the research community. In particular, this game-changing collaborative framework offers knowledge sharing from diverse data with a privacy-preserving. This chapter will discuss how federated learning can enable the development of an open health ecosystem with the support of AI. Existing challenges and solutions for federated learning will be discussed.
